Zobrazeno 1 - 10
of 4 717
pro vyhledávání: '"Wnt Pathway"'
Autor:
Wenlin Liu, Jie Wu, Yuanpu Lai, Siyi Zhang, Ankui Yang, Yixuan Li, Cuifang Chen, Zhongming Lu
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Laryngeal cancer (LCA) is one of the most common head and neck squamous cell carcinoma with poor outcome. LCA stem cells are the main reason for LCA therapy resistance and relapse. Understanding the molecular mechanisms of the sel
Externí odkaz:
https://doaj.org/article/0f505637185844af98c4023ce0b8991d
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract The WNT6 ligand is a well-known activator of the WNT signaling pathway, considered a vital player in several important physiologic processes during embryonic development and maintaining homeostasis throughout life, regulating the proliferati
Externí odkaz:
https://doaj.org/article/773c252a0f1545db8f2abc416cc65e21
lncRNA LINC02859 mediates Wnt pathway in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancer
Publikováno v:
环境与职业医学, Vol 41, Iss 10, Pp 1136-1143 (2024)
BackgroundGastric carcinogenesis is a multifactorial and complex process, in which long non-coding RNAs (lncRNAs) play important roles as oncogenes or antioncogenes. Research has found that the expression of lncRNA LINC02859 is down-regulated in gast
Externí odkaz:
https://doaj.org/article/31edb54537174a0a81bab7e57d1e5fdb
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract The long noncoding RNA (lncRNA)/Wingless (Wnt) axis is often dysregulated in digestive system tumors impacting critical cellular processes. Abnormal expression of specific Wnt-related lncRNAs such as LINC01606 (promotes motility), SLCO4A1-AS
Externí odkaz:
https://doaj.org/article/72e1db1b08e7457d9e330ccdfaa37fff
Autor:
Giulia Pozzati, Jinrui Zhou, Hananel Hazan, Giannoula Lakka Klement, Hava T. Siegelmann, Jack A. Tuszynski, Edward A. Rietman
Publikováno v:
Onco, Vol 4, Iss 3, Pp 163-191 (2024)
Whole-genome sequencing has revealed that TP53, NOTCH1, ATM, SF3B1, BIRC3, ABL, NXF1, BCR, and ZAP70 are often mutated in CLL, but not consistently across all CLL patients. This paper employs a statistical thermodynamics approach in combination with
Externí odkaz:
https://doaj.org/article/cbb7a77e2b574368b5b57277c1b9f346
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Background Chondrocyte viability, apoptosis, and migration are closely related to cartilage injury in osteoarthritis (OA) joints. Exosomes are identified as potential therapeutic agents for OA.Objective This study aimed to investigate the role of exo
Externí odkaz:
https://doaj.org/article/68142bd0f7e948789118e59ccff41279
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Lung cancer is one familiar cancer that threatens the lives of humans. circCTNNB1 has been disclosed to have regulatory functions in some diseases. However, the functions and related regulatory mechanisms of circCTNNB1 in lung cancer remain largely i
Externí odkaz:
https://doaj.org/article/2958a669d83f48c78989c4565682ed55
Publikováno v:
Klinicist, Vol 18, Iss 1, Pp 12-30 (2024)
Atherosclerosis is a chronic inflammatory vascular disease caused by various risk factors, in particular smoking, obesity, high blood pressure, and dyslipidemia. In addition, such signaling pathways as NLRP3 inflammasome, toll-like receptors, proprot
Externí odkaz:
https://doaj.org/article/12d8f6151e1f42b5b09708ec729a032f
Autor:
OuYang, Yin a, b, c, 1, Yi, Jian a, 1, Chen, Bowei a, 1, Zeng, Fanzuo a, c, Chen, Xuemei c, Yang, Hua a, c, Xu, Yaqian a, Liu, Zhenkui d, Ning, Wanling c, Liu, Baiyan b, c, ⁎
Publikováno v:
In Journal of Ethnopharmacology 13 January 2025 339
Autor:
Yunxiu Zhao, Yifei Lv, Yizhou Huang, Tao Zhang, Yibing Lan, Chunming Li, Peiqiong Chen, Wenxian Xu, Linjuan Ma, Jianhong Zhou
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37168- (2024)
The goal of the study was to explore the mechanism underlying the progression from abnormal uterine bleeding with ovulatory dysfunction (AUB-O) to AUB with atypical hyperplasia/malignancy (AUB-M). AUB-O, AUB-M and control endometrial tissues were sub
Externí odkaz:
https://doaj.org/article/e2d0b99ffcfc462885a2fc5e37586a15