Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wlodzimierz Matysiak"'
Autor:
Slawomir Mandziuk, Renata Gieroba, Agnieszka Korga, Wlodzimierz Matysiak, Barbara Jodlowska-Jedrych, Franciszek Burdan, Ewa Poleszak, Michał Kowalczyk, Luiza Grzycka-Kowalczyk, Elzbieta Korobowicz, Aleksandra Jozefczyk, Jaroslaw Dudka
Publikováno v:
Food & Nutrition Research, Vol 59, Iss 0, Pp 1-11 (2015)
Background: Doxorubicin (DOX) is an anticancer drug displaying cardiac and hepatic adverse effects mostly dependent on oxidative stress. Green tea (GT) has been reported to play a protective role in diseases resulting from oxidative stress. Objective
Externí odkaz:
https://doaj.org/article/88d3f1d6c60a4b649e9e88b127ba01a9
Autor:
Barbara Jodłowska-Jędrych, Magdalena Fituch, Justyna Halasa, Franciszek Burdan, Magdalena Iwan, Jarosław Dudka, Wlodzimierz Matysiak, Iwona Luszczewska-Sierakowska, Bartosz Czuba, Agnieszka Korga, Slawomir Mandziuk
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 27, Iss 4, Pp 220-223 (2014)
The main side effects of the administration of doxorubicin, a widely used anticancer drug, is the generation of a reactive oxygen species (ROS) in normal cells. As a result, redox disorders and secondary oxidative stress are developed. Doxorubicin RO
Autor:
Andrzej Wróbel, Agnieszka Korga, Ewa Poleszak, Magdalena Izdebska, Wlodzimierz Matysiak, Mariola Herbet, Barbara Jodłowska-Jędrych, Jarosław Dudka, Iwona Piątkowska-Chmiel, Monika Gawrońska-Grzywacz
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Chronic environmental stress is associated with reactive oxygen species (ROS) overproduction and the pathogenesis of depression. The purpose of this study was to evaluate biochemical and molecular changes associated with ROS generation in the brains
Autor:
Marcin Hejna, Agnieszka Korga, Wlodzimierz Matysiak, Slawomir Mandziuk, Malgorzata Oleksiejuk, Sylwia Tereszkiewicz, Magdalena Iwan, Jarosław Dudka, Agnieszka Korobowicz-Markiewicz
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 27, Iss 2, Pp 88-91 (2014)
The aim of the study was to verify the thesis that the cardiotoxic effects of doxorubicin are connected with activation of the ubiquitin - proteasome pathway followed by protein degradation. The expression of myocardial damage markers - fatty acid bi
Autor:
Renata Gieroba, Wlodzimierz Matysiak, Slawomir Mandziuk, Justyna Halasa, Barbara Jodłowska-Jędrych, Magdalena Iwan, Agnieszka Korga, Franciszek Burdan, Magdalena Wnukowska, Jarosław Dudka
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 28, Iss 1, Pp 5-7 (2015)
The redox cycle triggered by one electron reduction of doxorubicin and tirapazamine - both anticancer agents - leads to superoxide production. This superoxide production itself removes one iron atom from the [4Fe-4S] cluster, being an active center o
Autor:
Slawomir Mandziuk, Barbara Jodłowska-Jędrych, Agnieszka Korobowicz-Markiewicz, Agnieszka Korga, Michał Kowalczyk, Ewa Poleszak, Luiza Grzycka-Kowalczyk, Franciszek Burdan, Jarosław Dudka, Wlodzimierz Matysiak, Marcin Hejna, Iwona Pasnik
Publikováno v:
Basicclinical pharmacologytoxicology. 119(3)
Tirapazamine is a hypoxia-activated prodrug which was shown to exhibit up to 300 times greater cytotoxicity under anoxic in comparison with aerobic conditions. Thus, the combined anticancer therapy of tirapazamine with a routinely used anticancer dru
Autor:
Agnieszka Korobowicz-Markiewicz, Jarosław Dudka, Franciszek Burdan, Monika Cendrowska-Pinkosz, Magdalena Iwan, Barbara Madej-Czerwonka, Wlodzimierz Matysiak, Barbara Jodłowska-Jędrych, Agnieszka Korga
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2012 (2012)
Oxidative Medicine and Cellular Longevity, Vol 2012 (2012)
Cytochrome P450 NADPH-reductase (P450R), inducible synthase (iNOS) and xanthine oxidase play an important role in the antracycline-related cardiotoxicity. The expression of P450R and iNOS is regulated by triiodothyronine. The aim of this study was to
Autor:
Slawomir Mandziuk, Agnieszka Korga, Barbara Jodłowska-Jędrych, Franciszek Burdan, Wlodzimierz Matysiak, Justyna Sliwinska, Jarosław Dudka, Katarzyna Dawidek-Pietryka
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2012 (2012)
Doxorubicin (DOX) causes long-term cardiomyopathy that is dependent on oxidative stress and contractility disorders. Tirapazamine (TP), an experimental adjuvant drug, passes the same red-ox transformation as DOX. The aim of the study was to evaluate
Autor:
Wlodzimierz Matysiak, Jarosław Dudka, Franciszek Burdan, Elzbieta Korobowicz, Renata Gieroba, Slawomir Mandziuk, Marek Murias, Agnieszka Korga, Barbara Jodłowska-Jędrych
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
The aim of the study was to evaluate the effect of resveratrol in doxorubicin-induced cardiac and hepatic toxicity. Doxorubicin was administered once a week throughout the period of 7 weeks with 1.0 or 2.0 mg/kg body weight or concomitantly with resv
Autor:
Justyna, Sliwinska, Jaroslaw, Dudka, Agnieszka, Korga, Franciszek, Burdan, Wlodzimierz, Matysiak, Barbara, Jodlowska-Jedrych, Slawomir, Mandziuk, Katarzyna, Dawidek-Pietryka
Publikováno v:
Oxidative Medicine and Cellular Longevity
Doxorubicin (DOX) causes long-term cardiomyopathy that is dependent on oxidative stress and contractility disorders. Tirapazamine (TP), an experimental adjuvant drug, passes the same red-ox transformation as DOX. The aim of the study was to evaluate