Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Wladimiro, Jiménez"'
Autor:
Mireia Medrano-Bosch, Blanca Simón-Codina, Wladimiro Jiménez, Elazer R. Edelman, Pedro Melgar-Lesmes
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate inflammation, angiogenesis, or tissue remodeling. Monocytes
Externí odkaz:
https://doaj.org/article/6c10c569e8344db7aa85ca734e82f9f4
Autor:
Jordi Ribera, Irene Portolés, Bernat Córdoba-Jover, Juan Rodríguez-Vita, Gregori Casals, Bernardino González-de la Presa, Mariona Graupera, Estel Solsona-Vilarrasa, Carmen Garcia-Ruiz, José C. Fernández-Checa, Guadalupe Soria, Raúl Tudela, Anna Esteve-Codina, Guadalupe Espadas, Eduard Sabidó, Wladimiro Jiménez, William C. Sessa, Manuel Morales-Ruiz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Jordi Ribera et al. use zebrafish and mouse models to examine the role of the ATP-dependent RNA helicase, DHX15, in vascular health. Their results suggest that DHX15 depletion can cause vascular defects in vertebrates, potentially by impacting endoth
Externí odkaz:
https://doaj.org/article/60371e2857454f899a27accdb598b3f6
Autor:
Alazne Moreno-Lanceta, Mireia Medrano-Bosch, Blanca Simón-Codina, Montserrat Barber-González, Wladimiro Jiménez, Pedro Melgar-Lesmes
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1452 (2023)
Macrophages play essential roles during the progression of chronic liver disease. They actively participate in the response to liver damage and in the balance between fibrogenesis and regression. The activation of the PPARγ nuclear receptor in macro
Externí odkaz:
https://doaj.org/article/edd95e9aa11840528f6c104c74d88471
Autor:
Lena M. Ernst, Laura Mondragón, Joana Ramis, Muriel F. Gustà, Tetyana Yudina, Eudald Casals, Neus G. Bastús, Guillermo Fernández-Varo, Gregori Casals, Wladimiro Jiménez, Victor Puntes
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 765 (2023)
Nanoparticle (NP) pharmacokinetics significantly differ from traditional small molecule principles. From this emerges the need to create new tools and concepts to harness their full potential and avoid unnecessary risks. Nanoparticle pharmacokinetics
Externí odkaz:
https://doaj.org/article/7dd6ac6461cf496f97acc0d66699be14
Autor:
Bernat Córdoba-Jover, Altamira Arce-Cerezo, Jordi Ribera, Montse Pauta, Denise Oró, Gregori Casals, Guillermo Fernández-Varo, Eudald Casals, Victor Puntes, Wladimiro Jiménez, Manuel Morales-Ruiz
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background and aims Cerium oxide nanoparticles are effective scavengers of reactive oxygen species and have been proposed as a treatment for oxidative stress-related diseases. Consequently, we aimed to investigate the effect of these nanopar
Externí odkaz:
https://doaj.org/article/7f909eb33ae542cbac680be23ade6ce0
Autor:
Gregori Casals, Meritxell Perramón, Eudald Casals, Irene Portolés, Guillermo Fernández-Varo, Manuel Morales-Ruiz, Victor Puntes, Wladimiro Jiménez
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 660 (2021)
Oxidative stress induced by the overproduction of free radicals or reactive oxygen species (ROS) has been considered as a key pathogenic mechanism contributing to the initiation and progression of injury in liver diseases. Consequently, during the la
Externí odkaz:
https://doaj.org/article/a863764e4bb84326bc259e4bc3311827
Autor:
Santiago Marfà, Josep Marti, Adalgiza Reyes, Gregori Casals, Guillermo Fernández-Varo, Silvia Carvajal, J.C. García-Valdecasas, Josep Fuster, Wladimiro Jiménez
Publikováno v:
Translational Oncology, Vol 9, Iss 5, Pp 445-452 (2016)
Colorectal cancer (CRC) is one of the most common cancers in the developed countries, and nearly 70% of patients with CRC develop colorectal liver metastases (CRLMs). During the last decades, several scores have been proposed to predict recurrence af
Externí odkaz:
https://doaj.org/article/80fd6d8650d545c78e317fbf9cd10ded
Autor:
Santiago Marfà, Manuel Morales-Ruiz, Denise Oró, Jordi Ribera, Guillermo Fernández-Varo, Wladimiro Jiménez
Publikováno v:
Biology Open, Vol 5, Iss 6, Pp 858-865 (2016)
At present, several procedures are used for staging liver fibrosis. However, these methods may involve clinical complications and/or present diagnostic uncertainty mainly in the early stages of the disease. Thus, this study was designed to unveil new
Externí odkaz:
https://doaj.org/article/ea2f4d2268bd497aa471ec8d4340e3ca
Autor:
Jordi Ribera, Juan Rodríguez-Vita, Bernat Cordoba, Irene Portolés, Gregori Casals, Eudald Casals, Wladimiro Jiménez, Victor Puntes, Manuel Morales-Ruiz
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218716 (2019)
Background and aimsThe occurrence of endothelial alterations in the liver and in the splanchnic vasculature of cirrhotic patients and experimental models of liver diseases has been demonstrated. However, the pathological role of the portal vein endot
Externí odkaz:
https://doaj.org/article/2ad173d4eb174bffa36c382ed538d355
Autor:
Meritxell Perramón, Silvia Carvajal, Vedrana Reichenbach, Guillermo Fernández‐Varo, Loreto Boix, Laura Macias‐Muñoz, Pedro Melgar‐Lesmes, Jordi Bruix, Shlomo Melmed, Santiago Lamas, Wladimiro Jiménez
Publikováno v:
Liver International. 42:651-662
PTTG1 is almost undetectable in adult livers but is highly expressed in hepatocarcinoma. While little is known about its involvement in liver fibrosis, PTTG1 expression is associated with DLK1. We assessed the role of the PTTG1/DLK1 pathway in fibros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdef28c03464ceac0478cf514ed1f64
https://doi.org/10.1111/liv.15165
https://doi.org/10.1111/liv.15165