Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2 -Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.

Autor: Meijer TG; Department of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Department of Pathology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands., Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Prager-van der Smissen WJC; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Verkaik NS; Department of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands., Beaufort CM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., van Herk S; Oncode Institute, 3521 AL Utrecht, The Netherlands.; Department of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Robert-Finestra T; Oncode Institute, 3521 AL Utrecht, The Netherlands.; Department of Developmental Biology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Ruigrok-Ritstier K; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Paul MW; Department of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands., Gribnau J; Oncode Institute, 3521 AL Utrecht, The Netherlands.; Department of Developmental Biology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Bindels EMJ; Department of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Kanaar R; Department of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands., Jager A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., van Gent DC; Department of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.

Publikováno v: Cancers [Cancers (Basel)] 2024 Feb 10; Vol. 16 (4). Date of Electronic Publication: 2024 Feb 10.

Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile.

Autor: Smid M; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands., Prager-van der Smissen WJC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Ruigrok-Ritstier K; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Schreurs MAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Cornelissen S; Core Facility Molecular Pathology & Biobanking, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Garcia AM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Broeks A; Core Facility Molecular Pathology & Biobanking, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Timmermans AM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Trapman-Jansen AMAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands., Adank MA; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2023 May 09; Vol. 25 (1), pp. 53. Date of Electronic Publication: 2023 May 09.

Prospective Evaluation of a Circulating Tumor Cell Sensitivity Profile to Predict Response to Cisplatin Chemotherapy in Metastatic Breast Cancer Patients.

Autor: de Kruijff IE; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Sieuwerts AM; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Beije N; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Prager-van der Smissen WJC; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Angus L; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Beaufort CM; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Van MN; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Oomen-de Hoop E; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Jager A; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Hamberg P; Department of Medical Oncology, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands., de Jongh FE; Department of Medical Oncology, Ikazia Ziekenhuis, Rotterdam, Netherlands., Kraan J; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Martens JWM; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands., Sleijfer S; Department of Medical Oncology & Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands.

Publikováno v: Frontiers in oncology [Front Oncol] 2021 Jun 25; Vol. 11, pp. 697572. Date of Electronic Publication: 2021 Jun 25 (Print Publication: 2021).

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.

Autor: Liu J; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China., Prager-van der Smissen WJC; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ahearn TU; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Ambrosone CB; Roswell Park Cancer Institute, Buffalo, NY, USA., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Arnold N; Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.; Institute of Clinical Molecular Biology, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, Canada., Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Auvinen P; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland.; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland., Becher H; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Biometry and Clinical Epidemiology, Charité -Universitätsmedizin Berlin, Berlin, Germany., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Bernstein L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Bogdanova-Markov N; Institute of Human Genetics, University of Münster, Münster, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Partner Site Tübingen, Tübingen, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Partner Site Tübingen, Tübingen, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Briceno I; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Medical Faculty, Universidad de La Sabana, Bogota, Colombia., Brucker SY; Department of Gynecology and Obstetrics, University of Tübingen, Tübingen, Germany., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany., Burwinkel B; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Cai H; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Campa D; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Biology, University of Pisa, Pisa, Italy., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea., Christiaens M; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Dwek M; School of Life Sciences, University of Westminster, London, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, UK., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA., Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA., Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia., Goldberg MS; Department of Medicine, McGill University, Montréal, QC, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, QC, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Hartman M; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Surgery, National University Health System, Singapore, Singapore., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Hou MF; Department of Surgery, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Huo D; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA., Ito H; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan., Jakimovska M; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kang D; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea., Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Saint Petersburg State University, Saint-Petersburg, Russia., Kim SW; Department of Surgery, Daerim Saint Mary's Hospital, Seoul, Korea., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kristensen VN; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Kurian AW; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Li J; Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Luben RN; Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Mariapun S; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia., Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Meindl A; Department of Gynecology and Obstetrics, University of Munich, Campus Großhadern, Munich, Germany., Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, University College London, London, UK., Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia., Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Orr N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Ireland, UK., Park SK; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea., Peterlongo P; Genome Diagnostics Program, IFOM - the FIRC Institute for Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia., Presneau N; School of Life Sciences, University of Westminster, London, UK., Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Rau-Murthy R; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Rhenius V; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Ruebner M; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Schneeweiss A; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, Canada., Sohn C; National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany., Southey MC; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Spinelli JJ; Population Oncology, BC Cancer, Vancouver, BC, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada., Tamimi RM; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Torres D; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Untch M; Department of Gynecology and Obstetrics, Helios Clinics Berlin-Buch, Berlin, Germany., Vachon CM; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA., van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden., Yamaji T; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA., Ziv E; Department of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Martens JWM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.

Publikováno v: Scientific reports [Sci Rep] 2020 Jun 16; Vol. 10 (1), pp. 9688. Date of Electronic Publication: 2020 Jun 16.

The circular RNome of primary breast cancer.

Autor: Smid M; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Wilting SM; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Uhr K; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Rodríguez-González FG; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., de Weerd V; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Prager-Van der Smissen WJC; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., van der Vlugt-Daane M; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., van Galen A; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Nik-Zainal S; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.; East Anglian Medical Genetics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 9NB, United Kingdom., Butler A; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom., Martin S; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom., Davies HR; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom., Staaf J; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, SE-223 81 Lund, Sweden., van de Vijver MJ; Department of Pathology, Academic Medical Center, 1105AZ Amsterdam, the Netherlands., Richardson AL; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.; Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., MacGrogan G; Département de Biopathologie, Institut Bergonié, CS 61283 33076 Bordeaux, France., Salgado R; Breast Cancer Translational Research Laboratory, Université Libre de Bruxelles, Institut Jules Bordet, B-1000 Brussels, Belgium.; Department of Pathology/TCRU GZA, 2610 Antwerp, Belgium., van den Eynden GGGM; Department of Pathology/TCRU GZA, 2610 Antwerp, Belgium.; Molecular Immunology Unit, Jules Bordet Institute, B-1000 Brussels, Belgium., Purdie CA; Department of Pathology, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom., Thompson AM; Department of Pathology, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom., Caldas C; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Span PN; Department of Radiation Oncology, and Department of Laboratory Medicine, Radboud University Medical Center, 6525GA Nijmegen, the Netherlands., Sweep FCGJ; Department of Laboratory Medicine, Radboud University Medical Center, 6525GA Nijmegen, the Netherlands., Simpson PT; Centre for Clinical Research, Faculty of Medicine, The University of Queensland, 4029 Brisbane, Australia., Lakhani SR; Centre for Clinical Research, Faculty of Medicine, The University of Queensland, 4029 Brisbane, Australia.; Pathology Queensland, The Royal Brisbane and Women's Hospital, 4029 Brisbane, Australia., Van Laere S; Center for Oncological Research, University of Antwerp, 2610 Antwerp, Belgium., Desmedt C; Breast Cancer Translational Research Laboratory, Université Libre de Bruxelles, Institut Jules Bordet, B-1000 Brussels, Belgium., Paradiso A; Istituto Tumori G Paolo II, IRCCS, 70124 Bari, Italy., Eyfjord J; Cancer Research Laboratory, Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Broeks A; The Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Vincent-Salomon A; Institut Curie, Department of Pathology and INSERM U934, 75248 Paris Cedex 05, France., Futreal AP; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA., Knappskog S; Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.; Department of Oncology, Haukeland University Hospital, 5021 Bergen, Norway., King T; Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Viari A; Synergie Lyon Cancer, Centre Léon Bérard, Lyon Cedex 08, France.; Equipe Erable, INRIA Grenoble-Rhône-Alpes, 38330 Montbonnot-Saint Martin, France., Børresen-Dale AL; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radiumhospital, 0310 Oslo, Norway.; K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, 0310 Oslo, Norway., Stunnenberg HG; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, 6525GA Nijmegen, the Netherlands., Stratton M; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom., Foekens JA; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Sieuwerts AM; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands., Martens JWM; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, University Medical Center Rotterdam, Department of Medical Oncology, 3015GD Rotterdam, the Netherlands.

Publikováno v: Genome research [Genome Res] 2019 Mar; Vol. 29 (3), pp. 356-366. Date of Electronic Publication: 2019 Jan 28.