Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Witoon Tirasophon"'
Publikováno v:
Chiang Mai University Journal of Natural Sciences. 20
Eukaryotic cells have mechanisms to cope with stress in endoplasmic reticulum (ER) called unfolded protein response (UPR). In this study, we characterized putative X-box DNA binding protein1 (XBP1) and Binding protein (BiP) cDNAs from black tiger shr
Publikováno v:
Aquaculture. 482:65-72
In the past decade, RNA interference (RNAi) has emerged as a successful tool for functional genomics and anti-viral applications in shrimp. However, the mechanism of extracellular dsRNA uptake into shrimp cells has not been determined. Systemic RNA i
Publikováno v:
FEBS Letters. 591:406-414
Inositol-requiring enzyme 1 (IRE1) is a conserved sensor of the unfolded protein response that has protein kinase and endoribonuclease (RNase) enzymatic activities and thereby initiates HAC1/XBP1 splicing. Previous studies demonstrated that human IRE
Autor:
Piyanun Harnpicharnchai, Supattra Kitikhun, Sutipa Tanapongpipat, Takao Ohashi, Kittapong Sae-Tang, Niran Roongsawang, Kazuhito Fujiyama, Aekkachai Puseenam, Witoon Tirasophon
Publikováno v:
Applied Biochemistry and Biotechnology. 178:710-724
The thermotolerant methylotrophic yeast Ogataea thermomethanolica is a host for heterologous protein expression via secretion to the culture medium. Efficient secretion is a major bottleneck for heterologous protein production in this strain. To impr
Publikováno v:
Journal of Bioscience and Bioengineering. 120:470-475
Strong promoter is an essential factor for production of recombinant protein in various expression systems including Bacillus subtilis. In this study, we described a strategy to improve the expression efficiency using synthetic double promoter. Assem
Publikováno v:
Bioscience Reports
The unfolded protein response (UPR) is a conserved signalling pathway activated on the accumulation of unfolded proteins within the endoplasmic reticulum (ER), termed ER stress. Upon ER stress, HAC1/XBP1 undergoes exon/intron-specific excision by ino
Therapeutic inhibition of yellow head virus multiplication in infected shrimps by YHV-protease dsRNA
Autor:
Witoon Tirasophon, Sakol Panyim, Supansa Yodmuang, Nongluk Plongthongkum, Wanlop Chinnirunvong
Publikováno v:
Antiviral Research. 74:150-155
Yellow head virus (YHV) is an invertebrate nidovirus which causes a severe mortality in cultured Penaeus monodon. The mortality may be prevented by prior treatment of shrimps with YHV-protease dsRNA. Whether the YHV infected shrimp might be cured by
Publikováno v:
Biochemical and Biophysical Research Communications. 354:789-794
The ability of cells to survive and recover from deteriorating effects of endoplasmic reticulum (ER) stress relies on the unfolded protein response (UPR). The signaling pathway of Ire1p mediate mRNA splicing plays diverge role in UPR response in diff
Autor:
Niran Roongsawang, Lily Eurwilaichitr, Witoon Tirasophon, Sutipa Tanapongpipat, Peerada Promdonkoy
Publikováno v:
Current microbiology. 69(2)
Methanol-utilizing metabolism is generally found in methylotrophic yeasts. Several potential promoters regulating enzymes in this pathway have been extensively studied, especially alcohol oxidase. Here, we characterized the alcohol oxidase gene promo
Publikováno v:
Journal of Biological Chemistry. 275:3377-3381
Accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates signaling pathways to induce transcription of a number of genes encoding ER protein chaperones and-folding catalysts. In Saccharomyces cerevisiae this transcriptional induc