Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Witold Mozga"'
Publikováno v:
ACS Omega, Vol 6, Iss 40, Pp 26583-26600 (2021)
Externí odkaz:
https://doaj.org/article/90d3974f0f394994b24bc39605782fd7
Autor:
Julia Krzywik, Maral Aminpour, Ewa Maj, Witold Mozga, Joanna Wietrzyk, Jack A. Tuszyński, Adam Huczyński
Publikováno v:
Molecules, Vol 25, Iss 15, p 3540 (2020)
Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of
Externí odkaz:
https://doaj.org/article/b5735c84c2094c0ebb34c939bf9bf0df
Autor:
Julia Krzywik, Witold Mozga, Maral Aminpour, Jan Janczak, Ewa Maj, Joanna Wietrzyk, Jack A. Tuszyński, Adam Huczyński
Publikováno v:
Molecules, Vol 25, Iss 8, p 1789 (2020)
Colchicine is a well-known compound with strong antiproliferative activity that has had limited use in chemotherapy because of its toxicity. In order to create more potent anticancer agents, a series of novel colchicine derivatives have been obtained
Externí odkaz:
https://doaj.org/article/f0e90546c9b14f6b8c1bbbf819740b8f
Publikováno v:
ACS Omega, Vol 6, Iss 40, Pp 26583-26600 (2021)
ACS Omega
ACS Omega
A series of 1,4-disubstituted 1,2,3-triazoles having 10-demethoxy-10-N-methylaminocolchicine core were designed and synthesized via the Cu(I)-catalyzed "click" reaction and screened for their in vitro cytotoxicity against four cancer cell lines (A549
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e26df0baaae7173c9858f2ac1fa600
https://doaj.org/article/90d3974f0f394994b24bc39605782fd7
https://doaj.org/article/90d3974f0f394994b24bc39605782fd7
Autor:
Robert Koralewski, Michał Kowalski, Krzysztof Matyszewski, Sylwia Olejniczak, Piotr L. Sklepkiewicz, Michal Piotrowicz, Czestkowski Wojciech J, Michal Mlacki, Adam Golebiowski, Karolina Dzwonek, Barbara Dymek, Magdalena Salamon, Bartlomiej Borek, Piotr Niedziejko, Agnieszka Bartoszewicz, Marcin Nowotny, Agnieszka Zagozdzon, Mariusz Gruza, Agnieszka Napiorkowska-Gromadzka, Aneta Bartlomiejczak, Pawel Dobrzanski, Marzena Mazur, Gleb Andryianau, Magdalena Kania, Jakub Golab, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga, Marcin Mazurkiewicz, Tomasz Rejczak, Jacek Olczak, Sylwia Piasecka, Aleksandra Rymaszewska
Publikováno v:
Journal of Medicinal Chemistry. 63:15527-15540
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and inters...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dd9844a8fb40d1518481d781cdfd6d
https://doi.org/10.1021/acs.jmedchem.0c01179
https://doi.org/10.1021/acs.jmedchem.0c01179
Autor:
Robert, Koralewski, Barbara, Dymek, Marzena, Mazur, Piotr, Sklepkiewicz, Sylwia, Olejniczak, Wojciech, Czestkowski, Krzysztof, Matyszewski, Gleb, Andryianau, Piotr, Niedziejko, Michal, Kowalski, Mariusz, Gruza, Bartłomiej, Borek, Karol, Jedrzejczak, Agnieszka, Bartoszewicz, Elżbieta, Pluta, Aleksandra, Rymaszewska, Magdalena, Kania, Tomasz, Rejczak, Sylwia, Piasecka, Michal, Mlacki, Marcin, Mazurkiewicz, Michał, Piotrowicz, Magdalena, Salamon, Agnieszka, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Aneta, Bartlomiejczak, Witold, Mozga, Paweł, Dobrzański, Karolina, Dzwonek, Jakub, Golab, Marcin, Nowotny, Jacek, Olczak, Adam, Golebiowski
Publikováno v:
Journal of medicinal chemistry. 63(24)
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and interstitial lung diseases (ILDs), including idiopathic pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9418f8d294ee157abcdfd2a01099fe4
https://pubmed.ncbi.nlm.nih.gov/33078933
https://pubmed.ncbi.nlm.nih.gov/33078933
Autor:
Maral Aminpour, Ewa Maj, Witold Mozga, Adam Huczyński, Joanna Wietrzyk, Jack A. Tuszynski, Julia Krzywik
Publikováno v:
Molecules, Vol 25, Iss 3540, p 3540 (2020)
Molecules
Volume 25
Issue 15
Molecules
Volume 25
Issue 15
Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664595b994581e13ee43e111922a01c0
https://www.mdpi.com/1420-3049/25/15/3540
https://www.mdpi.com/1420-3049/25/15/3540
Autor:
Jack A. Tuszynski, Jan Janczak, Witold Mozga, Julia Krzywik, Joanna Wietrzyk, Adam Huczyński, Maral Aminpour, Ewa Maj
Publikováno v:
Molecules
Molecules, Vol 25, Iss 1789, p 1789 (2020)
Volume 25
Issue 8
Molecules, Vol 25, Iss 1789, p 1789 (2020)
Volume 25
Issue 8
Colchicine is a well-known compound with strong antiproliferative activity that has had limited use in chemotherapy because of its toxicity. In order to create more potent anticancer agents, a series of novel colchicine derivatives have been obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75921ca40947988e0587a574d8b835d
http://europepmc.org/articles/PMC7221574
http://europepmc.org/articles/PMC7221574
Autor:
Agnieszka Bartoszewicz, Aleksandra Rymaszewska, Agnieszka Zagozdzon, Jakub Golab, Pawel Dobrzanski, Marcin Mazurkiewicz, Filip Stefaniak, Czestkowski Wojciech J, Adam Golebiowski, Bartlomiej Borek, Karolina Dzwonek, Robert Koralewski, Piotr L. Sklepkiewicz, Krzysztof Matyszewski, Barbara Dymek, Sylwia Olejniczak, Marzena Mazur, Michał Piotrowicz, Magdalena Salamon, Jacek Olczak, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga
Publikováno v:
Journal of medicinal chemistry. 62(15)
Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals capable of cleaving the glycosidic bond in chitin. Based on the clinical findings and animal model studies, involvement of chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7391f2edfc78a24c715b46724e5643ef
https://pubmed.ncbi.nlm.nih.gov/31291098
https://pubmed.ncbi.nlm.nih.gov/31291098
Autor:
Jan Janczak, Witold Mozga, Mahshad Moshari, Jack A. Tuszynski, Maral Aminpour, Joanna Wietrzyk, Ewa Maj, Julia Krzywik, Adam Huczyński
Publikováno v:
European Journal of Medicinal Chemistry. 215:113282
Colchicine shows very high antimitotic activity, therefore, it is used as a lead compound for generation of new anticancer agents. In the hope of developing novel, useful drugs with more favourable pharmacological profiles, a series of doubly modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdeedab94d4c319acba719bebc036c4
https://doi.org/10.1016/j.ejmech.2021.113282
https://doi.org/10.1016/j.ejmech.2021.113282