Upstream alternative polyadenylation in SCN5A produces a short transcript isoform encoding a mitochondria-localized NaV1.5 N-terminal fragment that influences cardiomyocyte respiration.

Autor: Witmer NH, McLendon JM, Stein CS, Yoon JY, Berezhnaya E, Elrod JW, London BL, Boudreau RL

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 10. Date of Electronic Publication: 2024 Aug 10.

Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischemia-reperfusion injury.

Autor: Stein CS, Zhang X, Witmer NH, Pennington ER, Shaikh SR, Boudreau RL

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 01. Date of Electronic Publication: 2024 Jun 01.

Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson's disease.

Autor: Stein CS; Department of Internal Medicine, Iowa Neuroscience Institute, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., McLendon JM; Department of Internal Medicine, Iowa Neuroscience Institute, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Witmer NH; Program in Molecular Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Boudreau RL; Department of Internal Medicine, Iowa Neuroscience Institute, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Program in Molecular Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2022 Feb 12; Vol. 28, pp. 1-15. Date of Electronic Publication: 2022 Feb 12 (Print Publication: 2022).

Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency.

Autor: Stein CS; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Jadiya P; Center of Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Zhang X; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., McLendon JM; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Abouassaly GM; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Witmer NH; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Anderson EJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, College of Pharmacy, University of Iowa, Iowa City, IA, USA., Elrod JW; Center of Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Boudreau RL; Department of Internal Medicine, Fraternal Order of Eagles Diabetes Research Center, Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address: ryan-boudreau@uiowa.edu.

Publikováno v: Cell reports [Cell Rep] 2018 Jun 26; Vol. 23 (13), pp. 3710-3720.e8.

Deciphering the ghost proteome in ovarian cancer cells by deep proteogenomic characterization.

Autor: Garcia-del Rio, Diego Fernando, Derhourhi, Mehdi, Bonnefond, Amelie, Leblanc, Sébastien, Guilloy, Noé, Roucou, Xavier, Eyckerman, Sven, Gevaert, Kris, Salzet, Michel, Cardon, Tristan

Publikováno v: Cell Death & Disease; Sep2024, Vol. 15 Issue 9, p1-14, 14p