Pilot Study to Discover Candidate Biomarkers for Autism based on Perception and Production of Facial Expressions

Autor: Witherow, Megan A., Diawara, Norou, Keener, Janice, Harrington, John W., Iftekharuddin, Khan M.

Purpose: Facial expression production and perception in autism spectrum disorder (ASD) suggest potential presence of behavioral biomarkers that may stratify individuals on the spectrum into prognostic or treatment subgroups. Construct validity and gr

Externí odkaz: http://arxiv.org/abs/2404.16040

Gut microbe-generated phenylacetylglutamine is an endogenous allosteric modulator of β2-adrenergic receptors

Autor: Prasenjit Prasad Saha, Valentin Gogonea, Wendy Sweet, Maradumane L. Mohan, Khuraijam Dhanachandra Singh, James T. Anderson, Deepthi Mallela, Conner Witherow, Niladri Kar, Kate Stenson, Terri Harford, Michael A. Fischbach, J. Mark Brown, Sadashiva S. Karnik, Christine S. Moravec, Joseph A. DiDonato, Sathyamangla Venkata Naga Prasad, Stanley L. Hazen

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Allosteric modulation is a central mechanism for metabolic regulation but has yet to be described for a gut microbiota-host interaction. Phenylacetylglutamine (PAGln), a gut microbiota-derived metabolite, has previously been clinically assoc

Externí odkaz: https://doaj.org/article/135a6fb0bc4149b78a90558a91ecc051

Effect of PCI on Health Status in Ischemic Left Ventricular Dysfunction: Insights From REVIVED-BCIS2

Autor: Perera, Divaka, Chiribiri, Amedeo, Carr-White, Gerry, Pavlidis, Antonis, Redwood, Simon, Clapp, Brian, Rinaldi, Aldo, Rahman, Haseeb, Briceno, Natalia, Arnold, Sophie, Raynsford, Amy, Wilson, Karen, Clack, Lucy, Petrie, Mark, McEntegart, Margaret, Watkins, Stuart, Shaukat, Aadil, Rocchiccioli, Paul, McAdam, Marion, McPherson, Elizabeth, Cowan, Louise, Wood, Marie, Weerackody, Roshan, Davies, Ceri, Smith, Elliot, Modi, Bhavik, Mathew, Bindu, Mitchelmore, Oliver, Adrego, Rita, Andiapen, Mervyn, O’Kane, Peter, Din, Jehangir, Kennard, Sarah, Orr, Sarah, Purnell, Cathie, Greenwood, John, Blaxill, Jonathan, Mozid, Abdul, Anderson, Michelle, Somers, Kathryn, Dixon, Lana, Walsh, Simon, Spence, Mark, Glover, Patricia, Brown, Caroline, Edwards, Richard, McDiarmid, Adam, Egred, Mohaned, Narytnyk, Alla, Wealleans, Vera, Amin-Youssef, George, Shah, Ajay, McDonagh, Theresa, Byrne, Jonathan, Pareek, Nilesh, Breeze, Jonathan, Antao, Catherine, De Silva, Kalpa, Strange, Julian, Johnson, Tom, Nightingale, Angus, Gallego, Laura, Medina, Cristina, Gershlick, Anthony, McCann, Gerald, Ladwiniec, Andrew, Squire, Iain, Davison, Joanna, Kenmuir-Hogg, Kris, Spratt, James, Cosgrove, Claudia, Williams, Rupert, Firoozi, Sam, Lim, Pitt, Bonato, Giovanna, Sookhoo, Vennessa, Conway, Dwayne, Brooksby, Paul, Wright, Judith, Exley, Donna, Cotton, James, Horton, Richard, Metherell, Stella, Smallwood, Andrew, Hogrefe, Kai, Cheng, Adrian, Beirnes, Charmaine, Sidgwick, Sian, Lockie, Tim, Patel, Niket, Rakhit, Roby, Davies, Nina, Smit, Angelique, Ahmed, Fozia, Hendry, Cara, Fath-Odoubadi, Farzin, Fraser, Douglas, Mamas, Mamas, Oommen, Anu, Charles, Thabitha, Behan, Miles, Japp, Alan, Rif, Belinda, Jenkins, Nicholas, McClure, Sam, Oates, Pauline, Martin, Karen, Abdelaal, Eltigani, Sarma, Jaydeep, Shastri, Sanjay, Riley, Jo, Giannopoulou, Sarra, Quinn, Sophie, Magapu, Pradeep, Stables, Rod, Wright, David, Barton, Janet, Clarkson, Nichola, Mahmoudi, Michael, Flett, Andrew, Curzen, Nick, Radmore, Judith, Gough, Sam, Ludman, Andrew, Kurdi, Hibba, Keenan, Samantha, Banerjee, Prithwish, Tapp, Luke, Edwards, Nigel, Gibson, Catherine, Kukreja, Neville, Lynch, Mary, Barratt, Claire, de Belder, Mark, Thambyrajah, Jeet, Swanson, Neil, Richardson, Cath, Atkinson, Bev, Viswanathan, Girish, Waugh, Darren, Routledge, Helen, Trevelyan, Jasper, Doughty, Angela, Pegge, Nick, Dhamrait, Sukhbir, Moore, Sally, Galasko, Gavin, Cassidy, Christopher, Waddington, Natalia, Edwards, Tim, Iqbal, Javed, Witherow, Fraser, Birch, Jenny, Munro, Melanie, Wells, Tim, Sinha, Manas, Frost, Linda, Lee, Kaeng, Beattie, James, Pitt, Mike, Chung, Alan, Ramcharitar, Steve, McCafferty, Laura, Martin, Thomas, Irving, John, Iskandar, Zaid, Hutcheon, Anita, Gunn, Julian, Al-Mohammad, Abdallah, Agyemang, Michael, Griffiths, Huw, Kalra, Paul, Howe, Serena, Gray, Tim, Sobolewska, Jolanta, Morby, Louise, Glover, Jason, Beynon, James, Knight, Janet, Das, Paul, Bellamy, Chris, Harman, Emily, Pye, Maurice, Megarry, Simon, McGill, Yvonne, Redfearn, Heidi, Ryan, Matthew, Taylor, Dylan, Dodd, Matthew, Spertus, John A., Kosiborod, Mikhail N., Docherty, Kieran F., Clayton, Tim, Petrie, Mark C.

Publikováno v: In JACC: Heart Failure September 2024 12(9):1553-1562

Corrigendum: Safety, feasibility, tolerability, and clinical effects of repeated psilocybin dosing combined with non-directive support in the treatment of obsessive-compulsive disorder: protocol for a randomized, waitlist-controlled trial with blinded ratings

Autor: Terence H. W. Ching, Lucia Amoroso, Calvin Bohner, Elizabeth D'Amico, Jeffrey Eilbott, Tara Entezar, Madison Fitzpatrick, Geena Fram, Rachael Grazioplene, Jamila Hokanson, Anastasia Jankovsky, Stephen A. Kichuk, Bradford Martins, Prerana Patel, Henry Schaer, Sarah Shnayder, Chelsea Witherow, Christopher Pittenger, Benjamin Kelmendi

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

Externí odkaz: https://doaj.org/article/87400acead544d4daa95e5cbca2034a9

Effect of Text Processing Steps on Twitter Sentiment Classification using Word Embedding

Autor: Samad, Manar D., Khounviengxay, Nalin D., Witherow, Megan A.

Processing of raw text is the crucial first step in text classification and sentiment analysis. However, text processing steps are often performed using off-the-shelf routines and pre-built word dictionaries without optimizing for domain, application

Externí odkaz: http://arxiv.org/abs/2007.13027