Chiral N,N-Disubstituted Trifluoro-3-Amino-2-Propanols Are Potent Inhibitors of Cholesteryl Ester Transfer Protein

Autor: Durley, R. C., Grapperhaus, M. L., Hickory, B. S., Massa, M. A., Wang, J. L., Spangler, D. P., Mischke, D. A., Parnas, B. L., Fobian, Y. M., Rath, N. P., Honda, D. D., Zeng, M., Connolly, D. T., Heuvelman, D. M., Witherbee, B. J., Melton, M. A., Glenn, K. C., Krul, E. S., Smith, M. E., Sikorski, J. A.

Publikováno v: Journal of Medicinal Chemistry; August 2002, Vol. 45 Issue: 18 p3891-3904, 14p

Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein

Autor: Massa, M. A., Spangler, D. P., Durley, R. C., Hickory, B. S., Connolly, D. T., Witherbee, B. J., Smith, M. E., Sikorski, J. A.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 2001, Vol. 11 Issue: 13 p1625-1628, 4p

Stereospecific inhibition of CETP by chiral N,N-disubstituted trifluoro-3-amino-2-propanols.

Autor: Connolly DT; Pharmacia Discovery Research, 800 North Lindbergh Boulevard, St. Louis, Missouri 63167, USA. Daniel.T.Connelly@monsanto.com, Witherbee BJ, Melton MA, Durley RC, Grapperhaus ML, McKinnis BR, Vernier WF, Babler MA, Shieh JJ, Smith ME, Sikorski JA

Publikováno v: Biochemistry [Biochemistry] 2000 Nov 14; Vol. 39 (45), pp. 13870-9.