The effect of lumbar puncture on the neurodegeneration biomarker neurofilament light in macaque monkeys.

Autor: Boehnke SE; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada.; Department of Biomedical and Molecular Sciences Queen's University Kingston Ontario Canada., Robertson EL; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada., Armitage-Brown B; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada., Wither RG; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada., Lyra E Silva NM; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada., Winterborn A; Animal Care Services Queen's University Kingston Ontario Canada., Levy R; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada.; Department of Surgery Kingston General Hospital Kingston Ontario Canada., Cook DJ; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada.; Department of Surgery Kingston General Hospital Kingston Ontario Canada., De Felice FG; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada.; Department of Psychiatry Providence Care Hospital Kingston Ontario Canada.; Institute of Medical Biochemistry Leopoldo de Meis Federal University of Rio de Janeiro Rio de Janeiro Brazil., Munoz DP; Centre for Neuroscience Studies Queen's University Kingston Ontario Canada.; Department of Biomedical and Molecular Sciences Queen's University Kingston Ontario Canada.

Publikováno v: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2020 Jul 13; Vol. 12 (1), pp. e12069. Date of Electronic Publication: 2020 Jul 13 (Print Publication: 2020).

22q11.2 deletion syndrome lowers seizure threshold in adult patients without epilepsy.

Autor: Wither RG; Division of Neurology, Department of Medicine, Toronto Western Hospital, Krembil Neuroscience Centre, University of Toronto, Toronto, Ontario, Canada., Borlot F; Division of Neurology, Department of Medicine, Toronto Western Hospital, Krembil Neuroscience Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Neurology, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, U.S.A.; Krembil Neurosciences Epilepsy Genetics Program, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada., MacDonald A; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Butcher NJ; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada., Chow EWC; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Bassett AS; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Division of Cardiology, Department of Medicine, Dalglish Family Hearts and Minds Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Psychiatry, University Health Network, Toronto, Ontario, Canada.; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Andrade DM; Division of Neurology, Department of Medicine, Toronto Western Hospital, Krembil Neuroscience Centre, University of Toronto, Toronto, Ontario, Canada.; Krembil Neurosciences Epilepsy Genetics Program, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Publikováno v: Epilepsia [Epilepsia] 2017 Jun; Vol. 58 (6), pp. 1095-1101. Date of Electronic Publication: 2017 Apr 27.

A Role for Diminished GABA Transporter Activity in the Cortical Discharge Phenotype of MeCP2-Deficient Mice.

Autor: Zhang L; Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; University of Toronto Epilepsy Research Program, University of Toronto, Toronto, ON, Canada.; Department of Medicine (Neurology), University of Toronto, Toronto, ON, Canada., Wither RG; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Lang M; University of Toronto Epilepsy Research Program, University of Toronto, Toronto, ON, Canada.; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Wu C; Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada., Sidorova-Darmos E; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Netchev H; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada., Matolcsy CB; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada., Snead OC; University of Toronto Epilepsy Research Program, University of Toronto, Toronto, ON, Canada.; Department of Medicine (Neurology), University of Toronto, Toronto, ON, Canada., Eubanks JH; University of Toronto Epilepsy Research Program, University of Toronto, Toronto, ON, Canada.; Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada.; Department of Surgery (Neurosurgery), University of Toronto, Toronto, ON, Canada.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2016 May; Vol. 41 (6), pp. 1467-76. Date of Electronic Publication: 2015 Oct 26.

Differential expression of sirtuin family members in the developing, adult, and aged rat brain.

Autor: Sidorova-Darmos E; Division of Genetics and Development, Toronto Western Research Institute Toronto, ON, Canada ; Department of Physiology, University of Toronto Toronto, ON, Canada., Wither RG; Division of Genetics and Development, Toronto Western Research Institute Toronto, ON, Canada., Shulyakova N; Division of Genetics and Development, Toronto Western Research Institute Toronto, ON, Canada ; Department of Physiology, University of Toronto Toronto, ON, Canada., Fisher C; Department of Medical Biophysics, University of Toronto Toronto, ON, Canada., Ratnam M; Department of Cell Systems Biology, University of Toronto Toronto, ON, Canada., Aarts M; Department of Cell Systems Biology, University of Toronto Toronto, ON, Canada., Lilge L; Department of Medical Biophysics, University of Toronto Toronto, ON, Canada., Monnier PP; Division of Genetics and Development, Toronto Western Research Institute Toronto, ON, Canada ; Department of Physiology, University of Toronto Toronto, ON, Canada., Eubanks JH; Division of Genetics and Development, Toronto Western Research Institute Toronto, ON, Canada ; Department of Physiology, University of Toronto Toronto, ON, Canada ; Institute of Medical Sciences, University of Toronto Toronto, ON, Canada ; Department of Surgery (Neurosurgery), University of Toronto Toronto, ON, Canada.

Publikováno v: Frontiers in aging neuroscience [Front Aging Neurosci] 2014 Dec 18; Vol. 6, pp. 333. Date of Electronic Publication: 2014 Dec 18 (Print Publication: 2014).

Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation.

Autor: Lang M; Division of Genetics and Development and., Wither RG, Colic S, Wu C, Monnier PP, Bardakjian BL, Zhang L, Eubanks JH

Publikováno v: Human molecular genetics [Hum Mol Genet] 2014 Jan 15; Vol. 23 (2), pp. 303-18. Date of Electronic Publication: 2013 Sep 05.