Zobrazeno 1 - 10
of 1 269
pro vyhledávání: '"Wither A"'
Autor:
Sindhu R. Johnson, Hana Alahmari, Dennisse Bonilla, Zareen Ahmad, Arthur Bookman, Linda T. Hiraki, Earl Silverman, Zahi Touma, Mohammad Movahedi, Joan E. Wither
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 12, Pp 871-877 (2024)
Objective Our objective was to evaluate the development of a systemic autoimmune rheumatic disease (SARD) in undifferentiated and asymptomatic individuals with antinuclear antibodies (ANAs). We comparatively evaluated those who did and did not develo
Externí odkaz:
https://doaj.org/article/d003788e5d5b4b558c47cd71b6f6f122
Autor:
Dafna D Gladman, Murray Urowitz, Zahi Touma, Raphael Schneider, Joan Wither, Dennisse Bonilla, Laura Patricia Whittall Garcia
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 2 (2024)
Objective To determine if serum interferon (IFN)-α levels at the time of a lupus nephritis (LN) flare are associated with renal outcomes.Methods Patients with an LN flare who had a preflare estimated glomerular filtration rate (eGFR) ≥60 mL/min we
Externí odkaz:
https://doaj.org/article/8dc67a8259ba49a9b38295398904b763
Autor:
Dorcas Beaton, Maria Carmela Tartaglia, Jiandong Su, Michelle Barraclough, Zahi Touma, Robin Green, Patricia Katz, Ambika Gupta, Simone Appenzeller, Lesley Ruttan, Sindhu Johnson, Joan Wither, Dennisse Bonilla, May Choi, Andrea M Knight, Juan Pablo Díaz Martinez, Kathleen Bingham, Mahta Kakvan, Sherief Marzouk
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 2 (2024)
Objective To determine if self-reported fatigue, anxiety, depression, cognitive difficulties, health-related quality of life, disease activity scores and neuropsychological battery (NB) cluster into distinct groups in patients with SLE based on sympt
Externí odkaz:
https://doaj.org/article/b254fe970db44fcfab167e691ba0c6d9
Autor:
Xue Fan Wang, Robin Vigouroux, Michal Syonov, Yuriy Baglaenko, Angeliki M. Nikolakopoulou, Dene Ringuette, Horea Rus, Peter V. DiStefano, Suzie Dufour, Alireza P. Shabanzadeh, Seunggi Lee, Bernhard K. Mueller, Jason Charish, Hidekiyo Harada, Jason E. Fish, Joan Wither, Thomas Wälchli, Jean-François Cloutier, Berislav V. Zlokovic, Peter L. Carlen, Philippe P. Monnier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Liver failure causes breakdown of the Blood CNS Barrier (BCB) leading to damages of the Central-Nervous-System (CNS), however the mechanisms whereby the liver influences BCB-integrity remain elusive. One possibility is that the liver secrete
Externí odkaz:
https://doaj.org/article/863ced8c4fb94a3aaaf67d19e08288c8
Autor:
Murray Urowitz, Zahi Touma, Joan Wither, Laura Patricia Whittall-Garcia, Farnoosh Naderinabi, Ana Konvalinka
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Objective To determine if the serum levels of neutrophil extracellular trap (NET) remnants (Elastase-DNA and HMGB1-DNA complexes) at the time of a lupus nephritis (LN) flare predict renal outcomes in the following 24 months.Methods This was a retrosp
Externí odkaz:
https://doaj.org/article/31164ad9369b41fdb314882859b6d20d
Autor:
Dafna Gladman, Murray Urowitz, David Brooks, Zahi Touma, Joan Wither, Kieran Manion, Zoha Faheem, Carolina Munoz-Grajales, Giselle M Boukhaled, Carol Nassar, Mickael Kim
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/3a9227abc10e415eb96d334a7627ac2f
Autor:
Carolina Muñoz-Grajales, Michelle L. Barraclough, Juan P. Diaz-Martinez, Jiandong Su, Kathleen Bingham, Mahta Kakvan, Roberta Pozzi Kretzmann, Maria Carmela Tartaglia, Lesley Ruttan, May Y. Choi, Simone Appenzeller, Sherief Marzouk, Dennisse Bonilla, Patricia Katz, Dorcas Beaton, Robin Green, Dafna D. Gladman, Joan Wither, Zahi Touma
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
ObjectiveCognitive impairment (CI) is one of the most common manifestations of Neuropsychiatric Systemic Lupus Erythematosus (NPSLE). Despite its frequency, we have a limited understanding of the underlying immune mechanisms, resulting in a lack of p
Externí odkaz:
https://doaj.org/article/b1f2c06105f248018500a9273e93cd0e
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Autor:
Arjun Kumar, Kathleen Abadie, Elisa C Clark, Hao Yuan Kueh, Sriram Pendyala, Matthew Wither, Douglas Fowler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/44f4c68c124b44619a231b00b4fad8fe
Autor:
Dorcas Beaton, Maria Carmela Tartaglia, Jiandong Su, Michelle Barraclough, Zahi Touma, Robin Green, Lesley Ruttan, Joan Wither, Dennisse Bonilla, Kathleen Bingham, Mahta Kakvan, Mary Sano, Chrisanna Dobrowolski, Milica Tanic
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss 2 (2023)
Objective Cognitive dysfunction (CD) is detectable in approximately 40% of patients with SLE. Despite this high prevalence, there are no approved pharmacological treatment options for this detrimental condition. Preliminary murine studies show potent
Externí odkaz:
https://doaj.org/article/806e4ff7cc6e4496b76371756e695d32