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High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures.

Autor: Franzosa JA; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Bonzo JA; Cell Biology, Biosciences Division, Thermo Fisher Scientific, Frederick, MD, 21703, USA., Jack J; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Baker NC; Leidos, Research Triangle Park, NC, 27711, USA., Kothiya P; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Witek RP; Cell Biology, Biosciences Division, Thermo Fisher Scientific, Frederick, MD, 21703, USA., Hurban P; Expression Analysis, Durham, NC, 27713, USA., Siferd S; Expression Analysis, Durham, NC, 27713, USA., Hester S; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Shah I; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Ferguson SS; Division of National Toxicology Program, National Institutes of Environmental Health Sciences of National Institutes of Health, Durham, NC, 27709, USA., Houck KA; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA., Wambaugh JF; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, 27711, USA. Wambaugh.john@epa.gov.

Publikováno v: NPJ systems biology and applications [NPJ Syst Biol Appl] 2021 Jan 27; Vol. 7 (1), pp. 7. Date of Electronic Publication: 2021 Jan 27.

Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni.

Autor: Pereira TA; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, BA, Brazil.; Immunopathogesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,MD, United States of America., Syn WK; Section of Gastroenterology, Ralph H Johnson Veteran Affairs Medical Center, Charleston, South Carolina, United States of America.; Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, United States of America.; Liver Regeneration and Repair Research Group, Institute of Hepatology, Foundation for Liver Research, London, United Kingdom., Amâncio FF; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Cunha PH; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Caporali JF; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Trindade GV; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Department of Physiology, School of Medicine, National University of Ireland, Galway, Ireland., Santos ET; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, BA, Brazil., Souza MM; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, BA, Brazil., Andrade ZA; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, BA, Brazil., Witek RP; Thermo Fisher Scientific, Frederick, MD, United States of America., Secor WE; Centers for Disease Control and Prevention, Atlanta, GA, United States of America., Pereira FE; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, ES, Brazil., Lambertucci JR; Departamento de Clínica Médica, Laboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Diehl AM; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Oct 18; Vol. 10 (10), pp. e0005057. Date of Electronic Publication: 2016 Oct 18 (Print Publication: 2016).

Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.

Autor: Pereira TA; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A. Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz/FIOCRUZ, Salvador, BA 40296-710, Brazil., Syn WK; Liver Regeneration and Repair Research Group, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, U.K. Department of Surgery, Loyola University, Chicago, Maywood, IL 60153, U.S.A., Machado MV; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A., Vidigal PV; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Resende V; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Voieta I; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Xie G; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A., Otoni A; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Souza MM; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz/FIOCRUZ, Salvador, BA 40296-710, Brazil., Santos ET; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz/FIOCRUZ, Salvador, BA 40296-710, Brazil., Chan IS; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A., Trindade GV; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Choi SS; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A., Witek RP; Life Technologies, Frederick, MD 21704, U.S.A., Pereira FE; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, ES 29040-091, Brazil., Secor WE; Centers for Disease Control and Prevention, Atlanta, GA 30329, U.S.A., Andrade ZA; Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz/FIOCRUZ, Salvador, BA 40296-710, Brazil., Lambertucci JR; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG 30130-100, Brazil., Diehl AM; Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, U.S.A. diehl004@mc.duke.edu.

Publikováno v: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2015 Nov; Vol. 129 (10), pp. 875-83. Date of Electronic Publication: 2015 Jul 21.