Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Wisut Wichitnithad"'
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 2, Pp 295-311 (2023)
Over the last two years, global regulatory authorities have raised safety concerns on nitrosamine contamination in several drug classes, including angiotensin II receptor antagonists, histamine-2 receptor antagonists, antimicrobial agents, and antidi
Externí odkaz:
https://doaj.org/article/e74c7b71080f41d8a5bde65b551a745b
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 8, Pp 104951- (2023)
This study aimed to develop a sensitive and simple liquid chromatography-tandem mass spectrometry for the simultaneous determination of organic azido impurities (AZBC, AZBT, and AZTT) in sartan active pharmaceutical ingredients and drug products. The
Externí odkaz:
https://doaj.org/article/49e268ce91984c4caec76e52b9f81547
Autor:
Wisut Wichitnithad, Orawan Sudtanon, Pawadee Srisunak, Kamonrak Cheewatanakornkool, Siriwan Nantaphol, Pornchai Rojsitthisak
Publikováno v:
ACS Omega, Vol 6, Iss 16, Pp 11048-11058 (2021)
Externí odkaz:
https://doaj.org/article/5aae6fb93d694d2b9383b8155442e43a
Autor:
Nattapong Jongjitphisut, Worathat Thitikornpong, Wisut Wichitnithad, Thanundorn Thanusuwannasak, Opa Vajragupta, Pornchai Rojsitthisak
Publikováno v:
Molecules, Vol 28, Iss 4, p 1678 (2023)
A simple and reliable ultra-high-performance liquid chromatographic (UHPLC) method was developed and validated for determination of tetrahydrocurcumin diglutaric acid (TDG) and applied for evaluation of its bioaccessibility. The analytical method was
Externí odkaz:
https://doaj.org/article/df3fbe0c221e4162a3567acbdfa4274f
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04561- (2020)
A stability-indicating reversed-phase ultra-performance liquid chromatographic (UPLC) method for quantitative analysis of curcumin diethyl disuccinate (CDD) in raw materials was developed for applications in product development and quality control. C
Externí odkaz:
https://doaj.org/article/54e2320929ef461489e3a17b8800c25d
Autor:
Wisut Wichitnithad, Siriwan Nantaphol, Petploy Vicheantawatchai, Thanyaporn Kiatkumjorn, Wachirasak Wangkangwan, Pornchai Rojsitthisak
Publikováno v:
Pharmaceuticals, Vol 13, Iss 2, p 21 (2020)
This work demonstrated a sensitive, selective, and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantitation of sumatriptan in human plasma samples. Terazosin was used as an internal standard to minimize the variability
Externí odkaz:
https://doaj.org/article/e1ebcc7fba2a4e8491634106bb2f27aa
Autor:
Chawanphat Muangnoi, Pahweenvaj Ratnatilaka Na Bhuket, Ponsiree Jithavech, Wisut Wichitnithad, Onsiri Srikun, Chakkrapan Nerungsi, Suthiluk Patumraj, Pornchai Rojsitthisak
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 373 (2019)
Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds. CurDD was found to be more stable in a phospha
Externí odkaz:
https://doaj.org/article/f84a1fca0552401f9f8aa328cc03abbd
Publikováno v:
Molecules, Vol 16, Iss 2, Pp 1888-1900 (2011)
A novel series of succinyl derivatives of three curcuminoids were synthesized as potential prodrugs. Symmetrical (curcumin and bisdesmethoxycurcumin) and unsymmetrical (desmethoxycurcumin) curcuminoids were prepared through aldol condensation of 2,4-
Externí odkaz:
https://doaj.org/article/90d68a628e5445188f16c63491ba22e9
Autor:
Pornchai Rojsitthisak, Wisut Wichitnithad, Orawan Sudtanon, Kamonrak Cheewatanakornkool, Pawadee Srisunak, Siriwan Nantaphol
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 16, Pp 11048-11058 (2021)
ACS Omega, Vol 6, Iss 16, Pp 11048-11058 (2021)
Nitrosamine impurities in angiotensin II receptor antagonists (sartans) containing a tetrazole group represent an urgent concern for active pharmaceutical ingredient (API) manufacturers and global regulators. Regarding safety, API manufacturers must
Autor:
Wisut Wichitnithad, Siriwan Nantaphol, Kachathong Noppakhunsomboon, Worathat Thitikornpong, Pornchai Rojsitthisak
Publikováno v:
Talanta. 254:124102
Nitrosamine impurities in pharmaceuticals have recently been concerned for several national regulatory agencies to avoid carcinogenic and mutagenic effects in patients. The demand for highly sensitive and specific analytical methods with LOQs in the