Population pharmacokinetic and dynamic analysis of the topoisomerase I inhibitor lurtotecan in phase II studies

Autor: Schellens, J. H. M., Heinrich, B., Lehnert, M., Gore, M. E., Kaye, Stanley B., Dombernowsky, P., Paridaens, R., Oosterom, A. T. Van, Verweij, J., Loos, W. J., Calvert, H., Pavlidis, Nicholas, Cortes-Funes, H., Wanders, J., Roelvink, M., Sessa, Cristiana, Selinger, K., Wissel, P. S., Gamucci, T., Hanauske, A. R.

Publikováno v: Investigational new drugs
Investigational New Drugs, 20, 83-93. Kluwer Academic

Population pharmacokinetic-dynamic analysis was prospectively integrated in a broad phase II program of lurtotecan (GI147211), a novel camptothecin derived topoisomerase I inhibitor, to determine the population pharmacokinetic profile in a larger pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4799a8378ad320e230e7351b0dcee11f
https://gnosis.library.ucy.ac.cy/handle/7/41691

A comparison of the effects of a macrobiotic diet and a western diet on drug metabolism and plasma lipids in man

Autor: Wissel, P. S., Denke, M., Inturrisi, C. E.

Publikováno v: European Journal of Clinical Pharmacology; July 1987, Vol. 33 Issue: 4 p403-407, 5p

The Influence of Antineoplastic Chemotherapy on Antipyrine Metabolism in Man.

Autor: Wissel, P. S., Sordillo, P., Magill, G. B.

Publikováno v: Journal of Clinical Pharmacology; Mar1989, Vol. 29 Issue 3, p267-269, 3p

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A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors.

Autor: Planting AS; Department of Medical Oncology, Erasmus Medical Center/Daniel den Hoed Cancer Center, P.O. Box 5201, 3008 AE, Rotterdam, The Netherlands. a.s.t.planting@erasmusmc.nl, Sonneveld P, van der Gaast A, Sparreboom A, van der Burg ME, Luyten GP, de Leeuw K, de Boer-Dennert M, Wissel PS, Jewell RC, Paul EM, Purvis NB Jr, Verweij J

Publikováno v: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2005 Jan; Vol. 55 (1), pp. 91-9. Date of Electronic Publication: 2004 Jul 28.