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of 7
pro vyhledávání: '"Wissam B. Nassrallah"'
Autor:
Wissam B. Nassrallah, Daniel Ramandi, Judy Cheng, Jean Oh, James Mackay, Marja D. Sepers, David Lau, Hilmar Bading, Lynn A. Raymond
Publikováno v:
Neurobiology of Disease, Vol 189, Iss , Pp 106360- (2023)
Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD). A previous study showed Activin A, whose transcription is upr
Externí odkaz:
https://doaj.org/article/04dd3efbeedd46cd91625a37365c615f
Autor:
Amy I. Smith-Dijak, Wissam B. Nassrallah, Lily Y. J. Zhang, Michal Geva, Michael R. Hayden, Lynn A. Raymond
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Huntington disease (HD) is an inherited neurodegenerative disorder caused by a mutation in the huntingtin gene. The onset of symptoms is preceded by synaptic dysfunction. Homeostatic synaptic plasticity (HSP) refers to processes that maintain the sta
Externí odkaz:
https://doaj.org/article/e96ca48365e947b3aff8e9ccdb535974
Publikováno v:
Journal of Neuro-Ophthalmology.
Autor:
James P. Mackay, Amy I. Smith-Dijak, Ellen T. Koch, Peng Zhang, Evan Fung, Wissam B. Nassrallah, Caodu Buren, Mandi Schmidt, Michael R. Hayden, Lynn A. Raymond
Publikováno v:
The Journal of Neuroscience. :JN-RM
Action potential-independent (miniature) neurotransmission occurs at all chemical synapses, but remains poorly understood, particularly in pathological contexts. Axonal endoplasmic reticulum (ER) Ca2+stores are thought to influence miniature neurotra
Publikováno v:
CNS Neuroscience & Therapeutics. 24:301-310
Huntington's disease (HD) is a hereditary neurodegenerative disorder of typically middle-aged onset for which there is no disease-modifying treatment. Caudate and putamen medium-sized spiny projection neurons (SPNs) most severely degenerate in HD. Ho
Publikováno v:
CNS neurosciencetherapeutics. 24(4)
Huntington's disease (HD) is a hereditary neurodegenerative disorder of typically middle‐aged onset for which there is no disease‐modifying treatment. Caudate and putamen medium‐sized spiny projection neurons (SPNs) most severely degenerate in
Publikováno v:
IBRO Reports. 6:S35