Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wissam B. Nassrallah"'
Autor:
Wissam B. Nassrallah, Daniel Ramandi, Judy Cheng, Jean Oh, James Mackay, Marja D. Sepers, David Lau, Hilmar Bading, Lynn A. Raymond
Publikováno v:
Neurobiology of Disease, Vol 189, Iss , Pp 106360- (2023)
Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD). A previous study showed Activin A, whose transcription is upr
Externí odkaz:
https://doaj.org/article/04dd3efbeedd46cd91625a37365c615f
Autor:
Amy I. Smith-Dijak, Wissam B. Nassrallah, Lily Y. J. Zhang, Michal Geva, Michael R. Hayden, Lynn A. Raymond
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Huntington disease (HD) is an inherited neurodegenerative disorder caused by a mutation in the huntingtin gene. The onset of symptoms is preceded by synaptic dysfunction. Homeostatic synaptic plasticity (HSP) refers to processes that maintain the sta
Externí odkaz:
https://doaj.org/article/e96ca48365e947b3aff8e9ccdb535974
Publikováno v:
Journal of Neuro-Ophthalmology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4060641f8684067b2ea19eb8778f4af
https://doi.org/10.1097/wno.0000000000001887
https://doi.org/10.1097/wno.0000000000001887
Autor:
James P. Mackay, Amy I. Smith-Dijak, Ellen T. Koch, Peng Zhang, Evan Fung, Wissam B. Nassrallah, Caodu Buren, Mandi Schmidt, Michael R. Hayden, Lynn A. Raymond
Publikováno v:
The Journal of Neuroscience. :JN-RM
Action potential-independent (miniature) neurotransmission occurs at all chemical synapses, but remains poorly understood, particularly in pathological contexts. Axonal endoplasmic reticulum (ER) Ca2+stores are thought to influence miniature neurotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa501461f3b0a218a8f6be0d79df0d9
https://doi.org/10.1523/jneurosci.1593-22.2023
https://doi.org/10.1523/jneurosci.1593-22.2023
Publikováno v:
CNS Neuroscience & Therapeutics. 24:301-310
Huntington's disease (HD) is a hereditary neurodegenerative disorder of typically middle-aged onset for which there is no disease-modifying treatment. Caudate and putamen medium-sized spiny projection neurons (SPNs) most severely degenerate in HD. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beaa256eccd52d9ac9ad7f7a0b35f9a1
https://doi.org/10.1111/cns.12817
https://doi.org/10.1111/cns.12817
Publikováno v:
CNS neurosciencetherapeutics. 24(4)
Huntington's disease (HD) is a hereditary neurodegenerative disorder of typically middle‐aged onset for which there is no disease‐modifying treatment. Caudate and putamen medium‐sized spiny projection neurons (SPNs) most severely degenerate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d12af114702e692e8d7b9b8da3eafb6
https://pubmed.ncbi.nlm.nih.gov/29427371
https://pubmed.ncbi.nlm.nih.gov/29427371
Publikováno v:
IBRO Reports. 6:S35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272ba43f930c7edcab6fc51352502b54
https://doi.org/10.1016/j.ibror.2019.07.103
https://doi.org/10.1016/j.ibror.2019.07.103
Autor:
Nassrallah, Wissam B.1,2 (AUTHOR) wnassral@student.ubc.ca, Li, Hao Ran1,2 (AUTHOR) haoranli@student.ubc.ca, Irani, Lyden2 (AUTHOR) lyden2@student.ubc.ca, Wijesinghe, Printha2 (AUTHOR) printha.wijesinghe@ubc.ca, Hogg, Peter William3 (AUTHOR) peter.hogg@ubc.ca, Hui, Lucy1,2 (AUTHOR) lucyhui@student.ubc.ca, Oh, Jean1,2 (AUTHOR) ohjean@student.ubc.ca, Mackenzie, Ian R.4 (AUTHOR) Ian.Mackenzie@vch.ca, Hirsch-Reinshagen, Veronica4 (AUTHOR) Veronica.Hirsch@vch.ca, Hsiung, Ging-Yuek Robin5 (AUTHOR) robin.hsiung@ubc.ca, Pham, Wellington6 (AUTHOR) wellington.pham@Vanderbilt.Edu, Lee, Sieun7,8 (AUTHOR) Sieun.Lee@nottingham.ac.uk, Matsubara, Joanne A.2 (AUTHOR) jms@mail.ubc.ca
Publikováno v:
Acta Neuropathologica Communications. 12/24/2024, Vol. 12 Issue 1, p1-16. 16p.
Autor:
Mackay, James P., Smith-Dijak, Amy I., Koch, Ellen T., Peng Zhang, Fung, Evan, Nassrallah, Wissam B., Buren, Caodu, Schmidt, Mandi, Hayden, Michael R., Raymond, Lynn A.
Publikováno v:
Journal of Neuroscience; 5/17/2023, Vol. 43 Issue 20, p3743-3763, 21p
Publikováno v:
CNS Neuroscience & Therapeutics. Apr2018, Vol. 24 Issue 4, p301-310. 10p.