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Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer

Autor: Wisman, GBA, Knol, AJ, Helder, MN, Krans, M, de Vries, EGE, Hollema, H, de Jong, S, van der Zee, AGJ

Publikováno v: International Journal of Cancer, 91(5), 658-664. Wiley

We investigated, in cervical cancer, the relation between telomerase activity, telomerase RNA (hTR) and mRNA of the catalytic subunit of telomerase, hTERT, with "classic" clinicopathological factors as well as survival. Frozen specimens were obtained

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f9ed7773f97fcd3b144f57d914763784
https://research.rug.nl/en/publications/c30df252-6c3c-461a-8e20-5592fab76a53

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An SV40 large T-antigen immortalized human umbilical vein endothelial cell line for anti-endothelial cell antibody detection

Autor: van Leeuwen, EBM, Wisman, GBA, Tervaert, JWC, Palmans, LL, Molema, G, van der Zee, AGJ, van der Meer, J, Ruiters, MHJ, van Wijk, R., Veenstra, R.

Publikováno v: Clinical and Experimental Rheumatology, 19(3), 283-290. CLINICAL & EXPER RHEUMATOLOGY

Objective Anti-endothelial cell antibodies in serum of patients with different inflammatory diseases can be detected by, a whole cell enzyme-linked immunosorbant assay using primary cultures of human umbilical vein endothelial cells. To avoid repeate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::c9216b62142fe67dfe146f1a56b78ea5
https://research.rug.nl/en/publications/5259365a-a89e-4d31-8c43-eeb73b1a664f

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Telomerase in (pre)neoplastic cervical disease

Autor: Wisman, Gba, Jong, S., Meersma, Gj, Helder, Mn, Hollema, H., Vries, Ege, Nicol Keith, Zee, Agj

Publikováno v: Human Pathology, 31(10), 1304-1312. W B SAUNDERS CO-ELSEVIER INC
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This study was performed to determine upregulation of the human telomerase RNA component (hTR) and mRNA of the catalytic subunit of telomerase (hTERT) in (pre)malignant cervical lesions, to analyze possible intralesional heterogeneity of hTR expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ee990a9976217a73847b25259487f6a
https://research.rug.nl/en/publications/b19f26fa-8705-4ad0-bd35-146c9252e4b1

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Telomerase activity in needle biopsies from prostate cancer and benign prostates

Autor: Wymenga, LFA, Wisman, GBA, Ruiters, MHJ, Mensink, HJA, Veenstra, R.

Publikováno v: European Journal of Clinical Investigation, 30(4), 330-335. Wiley

Background Telomerase activation is thought to be essential for the immortality of cancer cells. It may be a prognostic factor in small volume well differentiated prostate cancers and hence a guide for the aggressiveness of the approach. The length o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1b08cbe0f241cfa1b5acff4a83143ccf
https://research.rug.nl/en/publications/c74c2dbc-7086-4f38-ac8f-1d6d574c6eee

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Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear

Autor: Wisman, GBA, Hollema, H, de Jong, S, ter Schegget, J, Tjong-A-Hung, SP, Ruiters, MHJ, Krans, M, de Vries, EGE, van der Zee, AGJ

Publikováno v: Journal of Clinical Oncology, 16(6), 2238-2245. AMER SOC CLINICAL ONCOLOGY

Purpose: To evaluate the diagnostic value of semiquantitative telomerase activity assessment in cervical scrapings together with human papillomavirus (HPV) typing for detection of (pre)neoplastic cervical lesions and to compare telomerase activity in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::b61bb03dfa9eedc98672cb1380bdb7e3
https://research.rug.nl/en/publications/fda4bfb2-1b4a-4379-a238-99b40f2247e8

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