Zobrazeno 1 - 10 of 217 pro vyhledávání: '"Wishka DG"'
1
Akademický článek
Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.
Autor: Morris J; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Kunkel MW; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., White SL; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Wishka DG; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Lopez OD; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Bowles L; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Sellers Brady P; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Ramsey P; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Grams J; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Rohrer T; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Martin K; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Dexheimer TS; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Coussens NP; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Evans D; Target Validation and Screening Laboratory, Applied and Developmental Research Directorate, Frederick National, Laboratory for Cancer Research, Frederick, Maryland., Risbood P; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Sonkin D; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Williams JD; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Polley EC; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Collins JM; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Doroshow JH; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland., Teicher BA; Division of Cancer Treatment and Diagnosis, NCI, Rockville, Maryland.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2023 Nov 01; Vol. 22 (11), pp. 1270-1279.
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2
Akademický článek
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor: SAR investigation around PNU-120596.
Autor: Acker BA; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Badescu VO; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Berkenpas MB; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Groppi VE; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Hajós M; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Higdon NR; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Hurst RS; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Jon Jacobsen E; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Margolis BJ; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., McWhorter WW; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Myers JK; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Piotrowski DW; Pfizer Worldwide Research & Development, Groton, CT 06340, USA. Electronic address: david.w.piotrowski@comcast.net., Rogers BN; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Sarapa D; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Vetman TN; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Walker DP; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Wall TM; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Wilhite DM; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Wishka DG; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Xu W; Pfizer Worldwide Research & Development, Groton, CT 06340, USA., Yates KM; Pfizer Worldwide Research & Development, Groton, CT 06340, USA.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Sep 01; Vol. 93, pp. 129433. Date of Electronic Publication: 2023 Aug 07.
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3
Akademický článek
F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd.
Autor: Morris J; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland. joel.morris@nih.gov., Wishka DG; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland., Lopez OD; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland., Rudchenko V; Alchem Laboratories Corporation, Alachua, Florida., Huang G; Alchem Laboratories Corporation, Alachua, Florida., Hoffman SN; Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland., Borgel S; Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland., Georgius K; Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland., Carter J; Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland., Stotler H; Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland., Kunkel MW; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland., Collins JM; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland., Hollingshead MG; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland., Teicher BA; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Apr; Vol. 20 (4), pp. 625-631.
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4
Akademický článek
The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D- erythro -pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (aza-T-dCyd) to support clinical development.
Autor: Wishka DG; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA.; Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Lopez OD; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA.; Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Rudchenko VF; Alchem Laboratories Corporation, Alachua, FL, USA., Huang G; Alchem Laboratories Corporation, Alachua, FL, USA., Bahde R; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA., Kumar V; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA., Denysenko SM; Alchem Laboratories Corporation, Alachua, FL, USA., Zhang L; Alchem Laboratories Corporation, Alachua, FL, USA., Zhang M; Alchem Laboratories Corporation, Alachua, FL, USA., Teicher BA; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA., Morris J; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, The National Cancer Institute, Rockville, MD, USA.
Publikováno v: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2021; Vol. 40 (1), pp. 68-95. Date of Electronic Publication: 2020 Oct 16.
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5
Akademický článek
Photocatalysed Synthesis and Structure Activity Evaluation of Cyclohexyloxyphenethylpyridinones as Potent HIV-1 Inhibitor.
Autor: Srivastava, Vishal1 (AUTHOR) vishalgreenchem@gmail.com, Tivari, Shraddha1 (AUTHOR), Singh, Pravin K.1 (AUTHOR), Singh, Praveen P.2 (AUTHOR)
Publikováno v: Catalysis Letters. Mar2024, Vol. 154 Issue 3, p771-779. 9p.
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6
Akademický článek
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7
Akademický článek
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
Autor: Alexander, Stephen P. H.1 (AUTHOR), Mathie, Alistair A.2 (AUTHOR), Peters, John A.3 (AUTHOR), Veale, Emma L.4 (AUTHOR), Striessnig, Jörg5 (AUTHOR), Kelly, Eamonn6 (AUTHOR), Armstrong, Jane F.7 (AUTHOR), Faccenda, Elena7 (AUTHOR), Harding, Simon D.7 (AUTHOR), Davies, Jamie A.7 (AUTHOR), Aldrich, Richard W.8 (AUTHOR), Attali, Bernard9 (AUTHOR), Baggetta, Austin M.10 (AUTHOR), Becirovic, Elvir11 (AUTHOR), Biel, Martin11 (AUTHOR), Bill, Roslyn M.12 (AUTHOR), Caceres, Ana I.13 (AUTHOR), Catterall, William A.14 (AUTHOR), Conner, Alex C.15 (AUTHOR), Davies, Paul16 (AUTHOR)
Publikováno v: British Journal of Pharmacology. Oct2023 Supplement 1, Vol. 180 Issue 2, pS145-S222. 78p. 1 Diagram.
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9
Akademický článek
The use of RNA-based treatments in the field of cancer immunotherapy.
Autor: Chehelgerdi, Mohammad1,2 (AUTHOR) Chehelgerdi1992@gmail.com, Chehelgerdi, Matin1,2 (AUTHOR)
Publikováno v: Molecular Cancer. 7/7/2023, Vol. 22 Issue 1, p1-104. 104p.
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10
Akademický článek
Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.
Autor: Montgomery JI; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, Connecticut 06340, United States. justin.montgomery@pfizer.com, Brown MF, Reilly U, Price LM, Abramite JA, Arcari J, Barham R, Che Y, Chen JM, Chung SW, Collantes EM, Desbonnet C, Doroski M, Doty J, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, McAllister L, McElroy E, Menard CA, Mitton-Fry M, Mullins L, Noe MC, O'Donnell J, Oliver R, Penzien J, Plummer M, Shanmugasundaram V, Thoma C, Tomaras AP, Uccello DP, Vaz A, Wishka DG
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2012 Feb 23; Vol. 55 (4), pp. 1662-70. Date of Electronic Publication: 2012 Feb 08.
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