Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Autor: Wishard , TM, Mutsaers, C. A., Riesland, Markus, Reimer, Michell Mario, Fuller, H.R., Hannam, Marie L, Morse, Robert, Young, Philip J, Lamont, D. J., Hammerschmidt, Matthias, Morris, G.E., Parson, Simon H., Skehel, Paul, Becker, Thomas, Robinson, Iain M, Becker, Catherina, Wirth, Brunhilde, Gillingwater, Thomas

Publikováno v: Wishard, TM, Mutsaers, C A, Riesland, M, Reimer, M M, Fuller, H R, Hannam, M L, Morse, R, Young, P J, Lamont, D J, Hammerschmidt, M, Morris, G E, Parson, S H, Skehel, P, Becker, T, Robinson, I M, Becker, C, Wirth, B & Gillingwater, T 2014, ' Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy ', Journal of Clinical Investigation . < https://www.jci.org/articles/view/71318 >

The autosomal recessive neurodegenerative disease spinal muscular atrophy (SMA) results from low levels of survival motor neuron (SMN) protein; however, it is unclear how reduced SMN promotes SMA development. Here, we determined that ubiquitin-depend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::21e45dd44dc11b6986559dbea59447df
https://www.pure.ed.ac.uk/ws/files/31114924/Dysregulation_of_Ubiquitin_Homeostasis_and_catenin_Signalling_Promote_Spinal_Muscular_Atrophy.pdf