Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Wiseman FK"'
2
Akademický článek
Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.
Autor: Wu Y; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Mumford P; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Noy S; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Mrzyglod A; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Luo D; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., van Dalen F; Department of Medical BioSciences, Radboudumc, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.; Institute for Chemical Immunology, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands., Verdoes M; Department of Medical BioSciences, Radboudumc, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.; Institute for Chemical Immunology, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands., Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Wiseman FK; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK. f.wiseman@ucl.ac.uk.
Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Aug 14; Vol. 11 (1), pp. 132. Date of Electronic Publication: 2023 Aug 14.
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3
Akademický článek
Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21.
Autor: Mumford P; The UK Dementia Research Institute, University College London, London, WC1N 3BG, United Kingdom., Tosh J; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Anderle S; The UK Dementia Research Institute, University College London, London, WC1N 3BG, United Kingdom., Gkanatsiou Wikberg E; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg S-431 80, Sweden., Lau G; The UK Dementia Research Institute, University College London, London, WC1N 3BG, United Kingdom., Noy S; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Saito T; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako-shi, Saitama Japan, 351-0198., Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako-shi, Saitama Japan, 351-0198., Yu E; Genetics and Genomics Program and Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Children's Guild Foundation Down Syndrome Research Program, Buffalo, New York NY 14263., Brinkmalm G; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg S-431 80, Sweden., Portelius E; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg S-431 80, Sweden., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg S-431 80, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal S-43180, Sweden., Zetterberg H; The UK Dementia Research Institute, University College London, London, WC1N 3BG, United Kingdom.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg S-431 80, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal S-43180, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, WC1N 3BG, United Kingdom.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China., Tybulewicz V; The Francis Crick Institute, London, NW1 1AT, United Kingdom.; Department of Immunology and Inflammation, Imperial College, London, W12 0NN, United Kingdom.; LonDownS: London Down Syndrome Consortium., Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom elizabeth.fisher@ucl.ac.uk f.wiseman@ucl.ac.uk.; LonDownS: London Down Syndrome Consortium., Wiseman FK; The UK Dementia Research Institute, University College London, London, WC1N 3BG, United Kingdom elizabeth.fisher@ucl.ac.uk f.wiseman@ucl.ac.uk.; LonDownS: London Down Syndrome Consortium.
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Aug 17; Vol. 42 (33), pp. 6453-6468. Date of Electronic Publication: 2022 Jul 14.
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4
Akademický článek
Rodent Modeling of Alzheimer's Disease in Down Syndrome: In vivo and ex vivo Approaches.
Autor: Farrell C; UK Dementia Research Institute at University College London, London, United Kingdom., Mumford P; UK Dementia Research Institute at University College London, London, United Kingdom., Wiseman FK; UK Dementia Research Institute at University College London, London, United Kingdom.
Publikováno v: Frontiers in neuroscience [Front Neurosci] 2022 Jun 07; Vol. 16, pp. 909669. Date of Electronic Publication: 2022 Jun 07 (Print Publication: 2022).
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5
Akademický článek
Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome.
Autor: Cannavo C; UK Dementia Research Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom., Cleverley K; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom., Maduro C; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom., Mumford P; UK Dementia Research Institute, UCL Queen Square Institute of Neurology, London, United Kingdom., Moulding D; Light Microscopy Core Facility, UCL Great Ormond Street Institute of Child Health, London, United Kingdom., Fisher EMC; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom., Wiseman FK; UK Dementia Research Institute, UCL Queen Square Institute of Neurology, London, United Kingdom.
Publikováno v: PloS one [PLoS One] 2022 May 11; Vol. 17 (5), pp. e0262558. Date of Electronic Publication: 2022 May 11 (Print Publication: 2022).
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6
Akademický článek
Cell models for Down syndrome-Alzheimer's disease research.
Autor: Wu Y; U.K. Dementia Research Institute, Institute of Neurology, University College London, London, U.K., West NR; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI 53705, U.S.A.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, U.S.A., Bhattacharyya A; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, U.S.A.; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, U.S.A., Wiseman FK; U.K. Dementia Research Institute, Institute of Neurology, University College London, London, U.K.; LonDownS Consortium, London, U.K.
Publikováno v: Neuronal signaling [Neuronal Signal] 2022 Apr 08; Vol. 6 (1), pp. NS20210054. Date of Electronic Publication: 2022 Apr 08 (Print Publication: 2022).
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7
Akademický článek
The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.
Autor: Wu Y; UK Dementia Research Institute at UCL, London, United Kingdom., Whittaker HT; Department of Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom., Noy S; Department of Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom., Cleverley K; Department of Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom., Brault V; Université de Strasbourg, CNRS, INSERM, Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France., Herault Y; Université de Strasbourg, CNRS, INSERM, Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France., Fisher EMC; Department of Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; LonDownS Consortium, London, United Kingdom., Wiseman FK; UK Dementia Research Institute at UCL, London, United Kingdom.; LonDownS Consortium, London, United Kingdom.
Publikováno v: PloS one [PLoS One] 2021 Jul 22; Vol. 16 (7), pp. e0242236. Date of Electronic Publication: 2021 Jul 22 (Print Publication: 2021).
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8
Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models.
Autor: Tosh JL; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.; The Francis Crick Institute, London, NW1 1AT, UK., Rhymes ER; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Mumford P; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Whittaker HT; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Pulford LJ; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Noy SJ; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Walker MC; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Tybulewicz VLJ; The Francis Crick Institute, London, NW1 1AT, UK.; Department of Immunology and Inflammation, Imperial College, London, W12 0NN, UK., Wykes RC; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.; Nanomedicine Lab and the Geoffrey Jefferson Brain Research Center, University of Manchester, Manchester, M13 9PT, UK., Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK. Elizabeth.fisher@ucl.ac.uk., Wiseman FK; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK. f.wiseman@ucl.ac.uk.
Publikováno v: Scientific reports [Sci Rep] 2021 Jul 16; Vol. 11 (1), pp. 14966. Date of Electronic Publication: 2021 Jul 16.
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9
Akademický článek
A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits.
Autor: Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK., Lee WC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK., Mumford P; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK.; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Collins T; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK., Rickman M; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK., Cunningham TJ; Mammalian Genetics Unit, Harwell, UK., Cleak J; Mammalian Genetics Unit, Harwell, UK., Mianne J; Mary Lyon Centre, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK., Szoke-Kovacs Z; Mary Lyon Centre, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK., Stewart M; Mammalian Genetics Unit, Harwell, UK., Teboul L; Mammalian Genetics Unit, Harwell, UK., Maduro C; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK., Wells S; Mary Lyon Centre, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK., Wiseman FK; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK.; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, London, UK. elizabeth.fisher@ucl.ac.uk.
Publikováno v: Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2021 Apr; Vol. 32 (2), pp. 94-103. Date of Electronic Publication: 2021 Mar 13.
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10
Akademický článek
Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models.
Autor: Tosh JL; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.; The Francis Crick Institute, London, NW1 1AT, UK., Rhymes ER; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Mumford P; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK., Whittaker HT; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Pulford LJ; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Noy SJ; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Walker MC; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Tybulewicz VLJ; The Francis Crick Institute, London, NW1 1AT, UK.; Department of Immunology and Inflammation, Imperial College, London, W12 0NN, UK., Wykes RC; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.; Nanomedicine Lab and the Geoffrey Jefferson Brain Research Center, University of Manchester, Manchester, M13 9PT, UK., Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK. Elizabeth.fisher@ucl.ac.uk., Wiseman FK; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK. F.wiseman@ucl.ac.uk.
Publikováno v: Scientific reports [Sci Rep] 2021 Mar 11; Vol. 11 (1), pp. 5736. Date of Electronic Publication: 2021 Mar 11.
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