Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Wise Wc"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 267:C1067-C1072
Lipopolysaccharide (LPS) induces macrophage protein and eicosanoid synthesis. Previous studies have shown that LPS induction of eicosanoid metabolism is transcription dependent and that prostaglandin (PG) H synthase is the committed step in the conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deed87c21347791170fa803303caa97
https://doi.org/10.1152/ajpcell.1994.267.4.c1067
https://doi.org/10.1152/ajpcell.1994.267.4.c1067
Autor:
Wise Wc, James A. Cook, G Matera, J. Geisel, A Focá, Perry V. Halushka, B A Berkowitz, Sarah Ashton
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:393-397
Magainins are novel polycationic peptides with broad-spectrum antimicrobial activity, including activity against gram-negative bacteria. Gram-negative bacteremia can elicit endotoxic shock that is associated with the increased formation of eicosanoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8361b5453f643886e7b1d973bcab8236
https://doi.org/10.1128/aac.37.3.393
https://doi.org/10.1128/aac.37.3.393
Publikováno v:
Pathophysiology of Shock, Sepsis, and Organ Failure ISBN: 9783642767388
The specific cellular and molecular mechanisms underlying the syndrome of endotoxemia and sep sis remain to be clearly defined. It is generally ac cepted that the release of inflammatory substances by the host rather than endotoxin itself mediates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e1928ba14aa3c6b7067a58caf8509c3
https://doi.org/10.1007/978-3-642-76736-4_38
https://doi.org/10.1007/978-3-642-76736-4_38
Publikováno v:
Host Defense Dysfunction in Trauma, Shock and Sepsis ISBN: 9783642774072
Endotoxin stimulates macrophages to synthesize and release a number of monokines including tumor necrosis factor (TNF), colony stimulating factor, platelet-activating factor, interleukin-1 (IL-1) and arachidonic acid metabolites [1–8]. In recent ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1504fc9169dfd78a666fd539abedb1f5
https://doi.org/10.1007/978-3-642-77405-8_109
https://doi.org/10.1007/978-3-642-77405-8_109
Publikováno v:
Journal of cardiovascular pharmacology. 17(1)
Repeated sublethal doses of endotoxin render rats tolerant to lethal doses of endotoxin and reduce thromboxane (Tx) A2 synthesis. Endotoxin-tolerant rats are also more resistant to lethal doses of U46619, a stable TxA2 mimetic. These observations rai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef93419e19e779226ebaf4b2a6ab13a
https://pubmed.ncbi.nlm.nih.gov/1708052
https://pubmed.ncbi.nlm.nih.gov/1708052
Publikováno v:
Pharmacological Research. 22:123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a5d188239825aaeaee082bbfcca87b
https://doi.org/10.1016/s1043-6618(09)80168-0
https://doi.org/10.1016/s1043-6618(09)80168-0
Publikováno v:
British Journal of Clinical Pharmacology; 1983, Vol. 15 Issue S1, p133S-139S, 7p
Publikováno v:
Journal of Clinical Investigation. 65:227-230
The potential deleterious role of the proaggregatory vasoconstrictor, thromboxane A(2), in endotoxic shock was investigated in rats. Plasma thromboxane A(2) was determined by radioimmunoassay of its stable metabolite thromboxane B(2). After intraveno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e0273663029d89600197345516f774
https://doi.org/10.1172/jci109655
https://doi.org/10.1172/jci109655
Publikováno v:
Journal of Cardiovascular Pharmacology. 8:514-519
Endotoxic shock is associated with increased metabolism of arachidonic acid to thromboxane (Tx) and prostaglandins. This investigation examined the effects of two structurally dissimilar inhibitors of (Tx) synthetase on Salmonella enteritidis endotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62cda2b6d8d47a0597f171565c179a5
https://doi.org/10.1097/00005344-198605000-00012
https://doi.org/10.1097/00005344-198605000-00012