Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wirthensohn DC"'
Autor:
Bongiovanni, MN, Godet, J, Horrocks, MH, Tosatto, L, Carr, AR, Wirthensohn, DC, Ranasinghe, RT, Lee, J-E, Ponjavic, A, Fritz, JV, Dobson, CM, Klenerman, D, Lee, SF
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Bongiovanni, M N, Godet, J, Horrocks, M H, Tosatto, L, Carr, A R, Wirthensohn, D C, Ranasinghe, R T, Lee, J, Ponjavic, A, Fritz, J V, Dobson, C M, Klenerman, D & Lee, S F 2016, ' Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping ', Nature Communications, vol. 7, 13544 . https://doi.org/10.1038/ncomms13544
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Bongiovanni, M N, Godet, J, Horrocks, M H, Tosatto, L, Carr, A R, Wirthensohn, D C, Ranasinghe, R T, Lee, J, Ponjavic, A, Fritz, J V, Dobson, C M, Klenerman, D & Lee, S F 2016, ' Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping ', Nature Communications, vol. 7, 13544 . https://doi.org/10.1038/ncomms13544
Super-resolution microscopy allows biological systems to be studied at the nanoscale, but has been restricted to providing only positional information. Here, we show that it is possible to perform multi-dimensional super-resolution imaging to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6dd8cf81c3429f09d086ab8481265fb8
http://europepmc.org/articles/PMC5155161
http://europepmc.org/articles/PMC5155161
Autor:
Flagmeier, P, De, S, Wirthensohn, DC, Lee, SF, Vincke, C, Muyldermans, S, Knowles, TPJ, Gandhi, S, Dobson, CM, Klenerman, D
To quantify and characterize the potentially toxic protein aggregates associated with neurodegenerative diseases, a high-throughput assay based on measuring the extent of aggregate-induced Ca(2+) entry into individual lipid vesicles has been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae962753a46c8f1592fd96728c3c97e
Autor:
Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Enderle M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Wirthensohn DC; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Miller A; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Schlesner M; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Pfeiffer F; Computational Biology Group, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Rittner A; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Oesterhelt D; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.
Publikováno v:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2019 Sep 01; Vol. 75 (Pt 9), pp. 576-585. Date of Electronic Publication: 2019 Aug 30.
Autor:
De S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. sd730@cam.ac.uk., Wirthensohn DC; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Flagmeier P; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Hughes C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK., Aprile FA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Ruggeri FS; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Whiten DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Emin D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Xia Z; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Varela JA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Sormanni P; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Kundel F; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Knowles TPJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Cavendish Laboratory, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 1HE, UK., Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Bryant C; Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK., Vendruscolo M; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. mv245@cam.ac.uk.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. mv245@cam.ac.uk., Klenerman D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. dk10012@cam.ac.uk.; UK Dementia Research Institute, University of Cambridge, Cambridge, CB2 0XY, UK. dk10012@cam.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2019 Apr 04; Vol. 10 (1), pp. 1541. Date of Electronic Publication: 2019 Apr 04.
Autor:
Whiten DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Zuo Y; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Calo L; Department of Clinical Neurosciences, University of Cambridge, Hills Road, Cambridge, CB2 0AH, UK., Choi ML; UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK., De S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Flagmeier P; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Wirthensohn DC; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Kundel F; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Ranasinghe RT; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Sanchez SE; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Athauda D; UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK., Lee SF; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Gandhi S; UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK., Spillantini MG; Department of Clinical Neurosciences, University of Cambridge, Hills Road, Cambridge, CB2 0AH, UK., Klenerman D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge, CB2 0XY, UK., Horrocks MH; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Present addresses: EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2018 Oct 04; Vol. 19 (19), pp. 2033-2038. Date of Electronic Publication: 2018 Sep 11.
Autor:
Kundel F; Department of Chemistry, University of Cambridge, UK., Tosatto L; Centre for Integrative Biology, Università degli Studi di Trento, Italy., Whiten DR; Department of Chemistry, University of Cambridge, UK., Wirthensohn DC; Department of Chemistry, University of Cambridge, UK., Horrocks MH; Department of Chemistry, University of Cambridge, UK., Klenerman D; Department of Chemistry, University of Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, UK.
Publikováno v:
The FEBS journal [FEBS J] 2018 Oct; Vol. 285 (19), pp. 3604-3630. Date of Electronic Publication: 2018 Mar 04.
Autor:
Drews A; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., De S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Flagmeier P; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Wirthensohn DC; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Chen WH; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Whiten DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Rodrigues M; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Vincke C; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium., Muyldermans S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium., Paterson RW; Dementia Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Slattery CF; Dementia Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Fox NC; Dementia Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Schott JM; Dementia Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Zetterberg H; Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Gandhi S; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Klenerman D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK; UK Dementia Research Institute, University of Cambridge, Cambridge CB2 0XY, UK. Electronic address: dk10012@cam.ac.uk.
Publikováno v:
Cell reports [Cell Rep] 2017 Dec 12; Vol. 21 (11), pp. 3310-3316.
Autor:
Flagmeier P; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., De S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Wirthensohn DC; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Lee SF; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Vincke C; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium., Muyldermans S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium., Knowles TPJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Gandhi S; Department of Molecular Neuroscience, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK., Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Klenerman D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Jun 26; Vol. 56 (27), pp. 7750-7754. Date of Electronic Publication: 2017 May 05.