Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Wioletta K. Glowacka"'
Publikováno v:
The Journal of Cell Biology
LAPTM5 is a lysosomal transmembrane protein expressed in immune cells. We show that LAPTM5 binds the ubiquitin-ligase Nedd4 and GGA3 to promote LAPTM5 sorting from the Golgi to the lysosome, an event that is independent of LAPTM5 ubiquitination. LAPT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386c7ae7659adb2497723243bec1b87a
https://doi.org/10.1083/jcb.200603001
https://doi.org/10.1083/jcb.200603001
LAPTM5 (lysosomal-associated protein transmembrane 5) is a protein that is preferentially expressed in immune cells, and it interacts with the Nedd4 family of ubiquitin ligases. Recent studies in T and B cells identified LAPTM5 as a negative regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c403b9420b9a9e1255157d9de28064
https://europepmc.org/articles/PMC3431655/
https://europepmc.org/articles/PMC3431655/
Autor:
Daniela Rotin, Bo-Yee Ngan, Aleixo M. Muise, Wei Xu, Wioletta K. Glowacka, Thomas D. Walters, Mark S. Silverberg, Anne M. Griffiths, Hui Lan
Publikováno v:
Gut. 58(8)
Background: Patients with Crohn’s disease have defects in intestinal epithelial permeability that are inadequately explained by known inflammatory bowel disease (IBD) susceptibility genes. E-cadherin ( CDH1 ) plays a vital role in maintaining the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fc16a65408d05f3fadcd9f160ee624
https://pubmed.ncbi.nlm.nih.gov/19398441
https://pubmed.ncbi.nlm.nih.gov/19398441