CONFORMATIONAL ANALYSIS OF FRAGMENT OF HUMAN PIN1 WW DOMAIN: INFLUENCE OF CHARGED AMINO-ACID RESIDUES ON β-HAIRPIN STRUCTURE

Autor: JOANNA MAKOWSKA, DOROTA UBER, WIOLETTA ŻMUDZIŃSKA, LECH CHMURZYŃSKI

Publikováno v: TASK Quarterly, Vol 18, Iss 4 (2014)

We examined the effect of like-charged residues on the conformation of an original nine amino-acid-residue fragment of the human Pin1 WW domain (hPin1) with the following sequence: Ac-Arg-Met-Ser-Arg-Ser-Ser-Gly-Arg-Val-NH2 (U9). This was facilitated

Externí odkaz: https://doaj.org/article/7018431b25ec48d5b7e9fb938a079910

Conformation-dependent affinity of Cu(II) ions peptide complexes derived from the human Pin1 protein

Autor: Joanna Makowska, Dorota Uber, Dariusz Wyrzykowski, Anna Maria Papini, Caterina Tiberi, Lech Chmurzyński, Wioletta Żmudzińska, Giuseppina Sabatino

Publikováno v: Journal of thermal analysis and calorimetry
127 (2017): 1431–1443. doi:10.1007/s10973-016-5387-9
info:cnr-pdr/source/autori:Uber, Dorota; Wyrzykowski, Dariusz; Tiberi, Caterina; Sabatino, Giuseppina; Zmudzinska, Wioletta; Chmurzynski, Lech; Papini, Anna Maria; Makowska, Joanna/titolo:Conformation-dependent affinity of Cu(II) ions peptide complexes derived from the human Pin1 protein ITC and DSC study/doi:10.1007%2Fs10973-016-5387-9/rivista:Journal of thermal analysis and calorimetry (Print)/anno:2017/pagina_da:1431/pagina_a:1443/intervallo_pagine:1431–1443/volume:127

The human Pin1 WW domain catalyzes the cis-trans isomerization of the proline peptide bond. In this study, the conformation and binding of Cu(II) ions by Pin1 were investigated. It has been found that the affinity of peptide fragments of the human Pi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4137e31b36d1578396f705d3016be3
https://doi.org/10.1007/s10973-016-5387-9

A general method for the derivation of the functional forms of the effective energy terms in coarse-grained energy functions of polymers. III. Determination of scale-consistent backbone-local and correlation potentials in the UNRES force field and force-field calibration and validation

Autor: Adam Liwo, Stanisław Ołdziej, Adam K. Sieradzan, Agnieszka G. Lipska, Wioletta Żmudzińska, Anna Hałabis, Cezary Czaplewski, InSuk Joung

Publikováno v: The Journal of Chemical Physics. 150:155104

The general theory of the construction of scale-consistent energy terms in the coarse-grained force fields presented in Paper I of this series has been applied to the revision of the UNRES force field for physics-based simulations of proteins. The po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623515733f05ff31e921601b610e0d48
https://doi.org/10.1063/1.5093015

Mechanism of formation of the C-terminal β-hairpin of the B3 domain of the immunoglobulin binding protein G fromStreptococcus. II. Interplay of local backbone conformational dynamics and long-range hydrophobic interactions in hairpin formation

Autor: Agnieszka Skwierawska, Stanisław Ołdziej, Harold A. Scheraga, Wioletta Żmudzińska, Adam Liwo

Publikováno v: Proteins: Structure, Function, and Bioinformatics. 76:637-654

Two peptides, corresponding to the turn region of the C-terminal beta-hairpin of the B3 domain of the immunoglobulin binding protein G from Streptococcus, consisting of residues 51-56 [IG(51-56)] and 50-57 [IG(50-57)], respectively, were studied by c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747270be0c9e342bc0f23eb35e8dd511
https://doi.org/10.1002/prot.22377

Characteristics of C-terminal, β-amyloid peptide binding fragment of neuroprotective protease inhibitor, cystatin C

Autor: Katarzyna Kalejta, Paulina Czaplewska, Aleksandra S. Kołodziejczyk, Wioletta Żmudzińska, Martyna Maszota-Zieleniak, Sylwia Rodziewicz-Motowidło, Marta Spodzieja

Publikováno v: Journal of Molecular Recognition. 30:e2581

Cystatin C originally identified as a cysteine proteases inhibitor has a broad spectrum of biological roles ranging from inhibition of extracellular cysteine protease activities, bone resorption, and modulation of inflammatory responses to stimulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c36766c1469ec79906ed895769a80da
https://doi.org/10.1002/jmr.2581