Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Winton Moy"'
Autor:
Siwei Zhang, Winton Moy, Hanwen Zhang, Catherine Leites, Heather McGowan, Jianxin Shi, Alan R. Sanders, Zhiping P. Pang, Pablo V. Gejman, Jubao Duan
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 88-98 (2018)
Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripote
Externí odkaz:
https://doaj.org/article/282ab3a710e04d33b4c870faabbe48ed
Autor:
Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D Figueroa, Victoria K Cortessis, Núria Malats, Margaret R Karagas, Paolo Vineis, I-Shou Chang, Dongxin Lin, Baosen Zhou, Adeline Seow, Keitaro Matsuo, Yun-Chul Hong, Neil E Caporaso, Brian Wolpin, Eric Jacobs, Gloria M Petersen, Alison P Klein, Donghui Li, Harvey Risch, Alan R Sanders, Li Hsu, Robert E Schoen, Hermann Brenner, MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium, PanScan Consortium, GAME-ON/ELLIPSE Consortium, Rachael Stolzenberg-Solomon, Pablo Gejman, Qing Lan, Nathaniel Rothman, Laufey T Amundadottir, Maria Teresa Landi, Douglas F Levinson, Stephen J Chanock, Nilanjan Chatterjee
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006493 (2016)
Recent heritability analyses have indicated that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex diseases based on polygenic risk score (PRS), a simple modelling technique that can be implement
Externí odkaz:
https://doaj.org/article/a59b3243ed1d40f794cbb7048b649f62
Autor:
Alan R. Sanders, Winton Moy, Harald H H Göring, Jubao Duan, Pablo V. Gejman, Mark Z. Kos, Eugene Drigalenko, Deli He, Jessica Freda
Publikováno v:
Translational Psychiatry
The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccf62af1dc6c236da7a612d0d84bb34
https://doi.org/10.1038/s41398-018-0216-5
https://doi.org/10.1038/s41398-018-0216-5
Autor:
Alan R. Sanders, Winton Moy, Jianxin Shi, Siwei Zhang, Pablo V. Gejman, Heather McGowan, Catherine Leites, Hanwen Zhang, Jubao Duan, Zhiping Pang
Publikováno v:
European Neuropsychopharmacology. 29:S799-S800
Background Allelic Imbalance of gene Expression (AIE) plays important role during neurodevelopment. However, the underlying mechanism of AIE has not been fully understood. Since chromatin accessibility (openness) has a strong influence on gene transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7edc489c836993412979def5ac039f02
https://doi.org/10.1016/j.euroneuro.2017.08.034
https://doi.org/10.1016/j.euroneuro.2017.08.034
Autor:
Winton Moy, Alan R. Sanders, Siwei Zhang, Jianxin Shi, Pablo V. Gejman, Heather McGowan, Hanwen Zhang, Jubao Duan, Catherine Leites, Zhiping P. Pang
Publikováno v:
Stem cell research
Stem Cell Research, Vol 29, Iss, Pp 88-98 (2018)
Stem Cell Research, Vol 29, Iss, Pp 88-98 (2018)
Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db425747cb5fdad8b6c20a0667d4f2a
https://pubmed.ncbi.nlm.nih.gov/29631039
https://pubmed.ncbi.nlm.nih.gov/29631039
Autor:
Winton Moy, Marc P. Forrest, Jubao Duan, Zhiping P. Pang, Pablo V. Gejman, Chad A. Cowan, Heather McGowan, Jianxin Shi, Catherine Leites, Peter Penzes, William J. Greenleaf, Alan R. Sanders, Hanwen Zhang
Publikováno v:
European Neuropsychopharmacology. 29:S765
Most disease variants lie within poorly-annotated noncoding parts of the genome, and their functional interpretation is challenging. To functionally assess the relevance of noncoding sequences in neuropsychiatric disorders, we hypothesized that disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c58182c296cfabe467552dd19a38f738
https://doi.org/10.1016/j.euroneuro.2017.06.122
https://doi.org/10.1016/j.euroneuro.2017.06.122
Autor:
M. T. Pato, Michael Gill, Patrick F. Sullivan, Harald H H Göring, Kimberly Chambert, Alan R. Sanders, Christina M. Hultman, Francis A. O'Neill, Douglas F. Levinson, Aiden Corvin, Ian Jones, Pamela Sklar, Pablo V. Gejman, Michael John Owen, Sophie E. Legge, Geraint Davies, Winton Moy, Michael Conlon O'Donovan, Jennifer L. Moran, Elaine K. Green, Derek W. Morris, Paul Cormican, Alexander Richards, Jubao Duan, George Kirov, Elliott Rees, Steven A. McCarroll, Giulio Genovese, Carlos N. Pato, Jing Shi, Kenneth S. Kendler, Nicholas John Craddock, Jin P. Szatkiewicz, Colm O'Dushlaine, James T.R. Walters, Brien P. Riley
Publikováno v:
Molecular Psychiatry; Vol 19
Rees, E, Kirov, G, Sanders, A, Walters, J T R, Chambert, K D, Shi, J, Szatkiewicz, J, O'Dushlaine, C, Richards, A L, Green, E K, Jones, I, Davies, G, Legge, S E, Moran, J L, Pato, C, Pato, M, Genovese, G, Levinson, D, Duan, J, Moy, W, Göring, H H H, Morris, D, Cormican, P, Kendler, K S, O'Neill, F A, Riley, B, Gill, M, Corvin, A, Wellcome Trust Case Control Consortium, Craddock, N, Sklar, P, Hultman, C, Sullivan, P F, Gejman, P V, McCarroll, S A, O'Donovan, M C & Owen, M J 2014, ' Evidence that duplications of 22q11.2 protect against schizophrenia ', Molecular Psychiatry, vol. 19, pp. 37-40 . https://doi.org/10.1038/mp.2013.156
Molecular Psychiatry
Rees, E, Kirov, G, Sanders, A, Walters, J T R, Chambert, K D, Shi, J, Szatkiewicz, J, O'Dushlaine, C, Richards, A L, Green, E K, Jones, I, Davies, G, Legge, S E, Moran, J L, Pato, C, Pato, M, Genovese, G, Levinson, D, Duan, J, Moy, W, Göring, H H H, Morris, D, Cormican, P, Kendler, K S, O'Neill, F A, Riley, B, Gill, M, Corvin, A, Wellcome Trust Case Control Consortium, Craddock, N, Sklar, P, Hultman, C, Sullivan, P F, Gejman, P V, McCarroll, S A, O'Donovan, M C & Owen, M J 2014, ' Evidence that duplications of 22q11.2 protect against schizophrenia ', Molecular Psychiatry, vol. 19, pp. 37-40 . https://doi.org/10.1038/mp.2013.156
Molecular Psychiatry
A number of large, rare copy number variants (CNVs) are deleterious for neurodevelopmental disorders, but large, rare, protective CNVs have not been reported for such phenotypes. Here we show in a CNV analysis of 47 005 individuals, the largest CNV a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303353d9d72ee07ebf6e00052028808b
https://doi.org/10.1038/mp.2013.156
https://doi.org/10.1038/mp.2013.156
Autor:
Jubao Duan, Winton Moy, Harvey A. Risch, Xing Hua, Nilanjan Chatterjee, Keitaro Matsuo, Sonja I. Berndt, Paolo Vineis, Margaret R. Karagas, Hermann Brenner, Robert E. Schoen, Maria Teresa Landi, Stephen J. Chanock, Debra T. Silverman, Kai Yu, Lei Song, Brian M. Wolpin, Jonine D. Figueroa, Neil E. Caporaso, Ju-Hyun Park, Victoria K. Cortessis, Chao A. Hsiung, Núria Malats, Pablo V. Gejman, Alison P. Klein, Alan R. Sanders, I-Shou Chang, Gloria M. Petersen, Baosen Zhou, Douglas F. Levinson, Li Hsu, Donghui Li, Qing Lan, Eric J. Jacobs, William Wheeler, Rachael Z. Stolzenberg-Solomon, Adeline Seow, Laufey T. Amundadottir, Montserrat Garcia-Closas, Jianxin Shi, Nathaniel Rothman, Dongxin Lin, Yun-Chul Hong, PanScan
Heritability analysis suggests that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex diseases. Polygenic risk-score (PRS) is a widely used modelling technique that requires only availability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f1f6fbd5789da7b1b24f28ee6426ec
Autor:
Pablo V. Gejman, Catherine Leites, Hanwen Zhang, Chad A. Cowan, Heather McGowan, Winton Moy, Jubao Duan, Zhiping P. Pang, Marc P. Forrest, Peter Penzes, William J. Greenleaf, Alan R. Sanders
Publikováno v:
European Neuropsychopharmacology. 27:S429-S430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bb8c9dc5a662fe38e85f7323c6f171a
https://doi.org/10.1016/j.euroneuro.2016.09.484
https://doi.org/10.1016/j.euroneuro.2016.09.484
Publikováno v:
Molecular Physics. 106:203-212
We combined finite size scaling method with the well-developed electronic structure methods, such as ab initio and density functional methods, to provide a systematic procedure for obtaining quantum critical parameters for atoms and molecules using G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56cae3fda015beff9c9d2c9b4569a9c2
https://doi.org/10.1080/00268970701528714
https://doi.org/10.1080/00268970701528714