The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus.

Autor: Wan, H.¹, Winton, H. L.¹, Soeller, C.¹, Taylor, G. W.², Gruenert, D. C.³, Thompson, P. J.⁴, Cannell, M. B.¹, Stewart, G. A.⁵, Garrod, D. R.⁶, Robinson, C.¹

Publikováno v: Clinical & Experimental Allergy. Feb2001, Vol. 31 Issue 2, p279-294. 16p.

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Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-.

Autor: Wan H; Dept of Pharmacology & Clinical Pharmacology, St George's Hospital Medical School, London, UK., Winton HL, Soeller C, Stewart GA, Thompson PJ, Gruenert DC, Cannell MB, Garrod DR, Robinson C

Publikováno v: The European respiratory journal [Eur Respir J] 2000 Jun; Vol. 15 (6), pp. 1058-68.

Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions.

Autor: Wan H; Department of Pharmacology and Clinical Pharmacology, St. George's Hospital Medical School, London SW17 0RE, United Kingdom., Winton HL, Soeller C, Tovey ER, Gruenert DC, Thompson PJ, Stewart GA, Taylor GW, Garrod DR, Cannell MB, Robinson C

Publikováno v: The Journal of clinical investigation [J Clin Invest] 1999 Jul; Vol. 104 (1), pp. 123-33.

Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium.

Autor: Winton HL; Department of Pharmacology & Clinical Pharmacology, St George's Hospital Medical School, London, UK., Wan H, Cannell MB, Thompson PJ, Garrod DR, Stewart GA, Robinson C

Publikováno v: British journal of pharmacology [Br J Pharmacol] 1998 Jul; Vol. 124 (6), pp. 1048-59.