Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Wintersinger"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101706- (2022)
Summary: Pairtree is a clone tree reconstruction algorithm that uses somatic point mutations to build clone trees describing the evolutionary history of individual cancers. Using the Pairtree software package, we describe steps to preprocess somatic
Externí odkaz:
https://doaj.org/article/5120ad9456f247bd96aaf353cfc31401
Akademický článek
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Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat mo
Externí odkaz:
https://doaj.org/article/2c2609169ffc489a95495823973de4eb
Autor:
Yulia Rubanova, Ruian Shi, Caitlin F. Harrigan, Roujia Li, Jeff Wintersinger, Nil Sahin, Amit Deshwar, PCAWG Evolution and Heterogeneity Working Group, Quaid Morris, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cancers evolve as they progress under differing selective pressures. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, the authors present the method TrackSig the estimates evolutionary trajectories of somatic mu
Externí odkaz:
https://doaj.org/article/1a3e0a924fa54deda33cd083d4a87624
Autor:
Yulia Rubanova, Ruian Shi, Caitlin F. Harrigan, Roujia Li, Jeff Wintersinger, Nil Sahin, Amit G. Deshwar, PCAWG Evolution and Heterogeneity Working Group, Quaid D. Morris, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/91723d08c5e440508381ec45a0173252
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008400 (2021)
Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how cancers develop and respond to treatment. Subclonal reconstruction methods cluster mutations i
Externí odkaz:
https://doaj.org/article/2e2c7a038087427aaf69ce77002b06e4
Autor:
Christopher M. Wintersinger, Dionis Minev, Anastasia Ershova, Hiroshi M. Sasaki, Gokul Gowri, Jonathan F. Berengut, F. Eduardo Corea-Dilbert, Peng Yin, William M. Shih
Publikováno v:
Nature Nanotechnology. 18:281-289
Autor:
Quaid Morris, John E. Dick, Lincoln D. Stein, Ethan Kulman, Stephanie M. Dobson, Jeff A. Wintersinger
Supplementary Data from Reconstructing Complex Cancer Evolutionary Histories from Multiple Bulk DNA Samples Using Pairtree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516ceb18dbff5efc188238e75efe31b6
https://doi.org/10.1158/2643-3230.22544141
https://doi.org/10.1158/2643-3230.22544141
Autor:
Quaid Morris, John E. Dick, Lincoln D. Stein, Ethan Kulman, Stephanie M. Dobson, Jeff A. Wintersinger
Cancers are composed of genetically distinct subpopulations of malignant cells. DNA-sequencing data can be used to determine the somatic point mutations specific to each population and build clone trees describing the evolutionary relationships betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be670c6b73edffb373297722824c659f
https://doi.org/10.1158/2643-3230.c.6550547
https://doi.org/10.1158/2643-3230.c.6550547
Autor:
John E. Dick, Charles G. Mullighan, Quaid Morris, Mark D. Minden, Jinghui Zhang, Jayne S. Danska, Cynthia J. Guidos, John Easton, Gary Bader, Steven M. Chan, Geoffrey Neale, Scott R. Olsen, Ying Shao, Michael Rusch, Pankaj Gupta, Sagi Abelson, Mohsen Hosseini, Stephanie Z. Xie, Michelle Chan-Seng-Yue, Veronique Voisin, Yiping Fan, Xiaotu Ma, Michael N. Edmonson, Debbie Payne-Turner, Ildiko Grandal, Olga I. Gan, Jessica McLeod, Zhaohui Gu, Esmé Waanders, Jeffrey Wintersinger, Robert J. Vanner, Laura García-Prat, Stephanie M. Dobson
Targeted-sequencing analysis of PDX and PairTree predicted mutational population clusters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823eb2ad063b0558407f0bcc5e8a0bf0
https://doi.org/10.1158/2159-8290.22535185
https://doi.org/10.1158/2159-8290.22535185