Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells

Autor: Jiajia Xu, Yiyun Wang, Ching-Yun Hsu, Stefano Negri, Robert J Tower, Yongxing Gao, Ye Tian, Takashi Sono, Carolyn A Meyers, Winters R Hardy, Leslie Chang, Shuaishuai Hu, Nusrat Kahn, Kristen Broderick, Bruno Péault, Aaron W James

Publikováno v: eLife, Vol 9 (2020)

Tissue resident mesenchymal stem/stromal cells (MSCs) occupy perivascular spaces. Profiling human adipose perivascular mesenchyme with antibody arrays identified 16 novel surface antigens, including endolysosomal protein CD107a. Surface CD107a expres

Externí odkaz: https://doaj.org/article/4b6fc769da414823962e1b24d2495680

Comparison of Human Tissue Microarray to Human Pericyte Transcriptome Yields Novel Perivascular Cell Markers

Autor: Sarah Miller, Aaron W. James, Winters R. Hardy, Catherine Ding, Ching Yun Hsu, Bruno Péault, Carolyn A. Meyers, Mario Gomez Salazar

Publikováno v: Stem Cells Dev

Human perivascular progenitor cells, including pericytes, are well-described multipotent mesenchymal cells giving rise to mesenchymal stem cells in culture. Despite the unique location of pericytes, specific antigens to distinguish human pericytes fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06057e6dad2b363a62f4d1800640f2f7
https://doi.org/10.1089/scd.2019.0106

Author response: Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells

Autor: Stefano Negri, Ching Yun Hsu, Yongxing Gao, Kristen P. Broderick, Leslie Chang, Yiyun Wang, Ye Tian, Nusrat Kahn, Winters R. Hardy, Carolyn A. Meyers, Robert J. Tower, Bruno Péault, Shuaishuai Hu, Aaron W. James, Takashi Sono, Jiajia Xu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::428987fd65fd37aab2c65f07f5e5fa0d
https://doi.org/10.7554/elife.58990.sa2

Isolation and characterization of canine perivascular stem/stromal cells for bone tissue engineering

Autor: Mihaela Crisan, Greg Asatrian, Erin Zou, Venu Lagishetty, Winters R. Hardy, Kang Ting, Xinli Zhang, Pei Liang, Sonja Lobo, Catherine Ding, Martin K. Childers, Carolyn A. Meyers, Bruno Péault, Yu Hsin Yen, Aaron W. James, Chia Soo

Publikováno v: James, A W, Zhang, X, Crisan, M, Hardy, W R, Liang, P, Meyers, C A, Lobo, S, Lagishetty, V, Childers, M K, Asatrian, G, Ding, C, Yen, Y-H, Zou, E, Ting, K, Peault, B & Soo, C 2017, ' Isolation and characterization of canine perivascular stem/stromal cells for bone tissue engineering ', PLoS ONE, vol. 12, no. 5, pp. e0177308 . https://doi.org/10.1371/journal.pone.0177308
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0177308 (2017)

For over 15 years, human subcutaneous adipose tissue has been recognized as a rich source of tissue resident mesenchymal stem/stromal cells (MSC). The isolation of perivascular progenitor cells from human adipose tissue by a cell sorting strategy was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad43a3d8feda588129f8b1957073bc43
https://hdl.handle.net/20.500.11820/11389318-0d95-4fdf-9bd5-d6810db09dee

Nature or Nurture

Autor: Winters R. Hardy, Aaron W. James, Arnold I. Caplan, Greg Asatrian, Bruno Péault, Alvaro Santamaria, Kang Ting, Chia Soo, William C.W. Chen

Mesenchymal stem cells (MSCs) have been and remain very popular among cell therapists and tissue engineers, as shown by the use thereof in over 500 clinical trials. This success is justified by the diverse positive contributions exerted by MSCs towar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03ab1a2e42750fce25079dc7926138d
https://doi.org/10.1016/b978-0-12-800548-4.00015-2