More than the SRY: The Non-Coding Landscape of the Y Chromosome and Its Importance in Human Disease.

Autor: Westemeier-Rice ES; West Virginia University Cancer Institute, West Virginia University School of Medicine, Morgantown, WV 26506, USA., Winters MT; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA., Rawson TW; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA., Martinez I; West Virginia University Cancer Institute, West Virginia University School of Medicine, Morgantown, WV 26506, USA.; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA.

Publikováno v: Non-coding RNA [Noncoding RNA] 2024 Apr 10; Vol. 10 (2). Date of Electronic Publication: 2024 Apr 10.

Obesity and metabolic dysfunction drive sex-associated differential disease profiles in hACE2-mice challenged with SARS-CoV-2.

Autor: Lee KS; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Russ BP; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Wong TY; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Horspool AM; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Winters MT; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA., Barbier M; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Bevere JR; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Martinez I; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; West Virginia University Cancer Institute, School of Medicine, Morgantown, WV, USA., Damron FH; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, USA.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA., Cyphert HA; Department of Biological Sciences, Marshall University, Huntington, WV, USA.

Publikováno v: IScience [iScience] 2022 Oct 21; Vol. 25 (10), pp. 105038. Date of Electronic Publication: 2022 Sep 02.

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice.

Autor: Lee KS; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Wong TY; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Russ BP; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Horspool AM; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Miller OA; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Rader NA; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Givi JP; Department of Pathology, Anatomy, and Laboratory Medicine, West Virginia University, Morgantown, WV, United States of America., Winters MT; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America., Wong ZYA; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Cyphert HA; Department of Biological Sciences, Marshall University, Huntington, WV, United States of America., Denvir J; Department of Biomedical Sciences, Marshall University, Huntington, WV, United States of America., Stoilov P; Department of Biochemistry, School of Medicine, West Virginia University Morgantown, Morgantown, WV, United States of America., Barbier M; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Roan NR; Department or Urology, University of California, San Francisco, San Francisco, CA, United States of America.; Gladstone Institute of Virology, San Francisco, CA, United States of America., Amin MS; Department of Pathology, Anatomy, and Laboratory Medicine, West Virginia University, Morgantown, WV, United States of America., Martinez I; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; West Virginia University Cancer Institute, School of Medicine, Morgantown, WV, United States of America., Bevere JR; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America., Damron FH; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States of America.; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, United States of America.

Publikováno v: PloS one [PLoS One] 2022 Aug 29; Vol. 17 (8), pp. e0273430. Date of Electronic Publication: 2022 Aug 29 (Print Publication: 2022).

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice.

Autor: Wong TY; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Horspool AM; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Russ BP; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Ye C; Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institutegrid.250889.e, San Antonio, Texas, USA., Lee KS; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Winters MT; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA., Bevere JR; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Miller OA; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Rader NA; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Cooper M; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Kieffer T; Department of Pathology, Anatomy and Laboratory Medicine, West Virginia Universitygrid.268154.c School of Medicine, Morgantown, West Virginia, USA., Sourimant J; Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA., Greninger AL; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA., Plemper RK; Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA., Denvir J; Department of Biomedical Sciences, Marshall Universitygrid.259676.9, Huntington, West Virginia, USA., Cyphert HA; Department of Biological Sciences, Marshall Universitygrid.259676.9, Huntington, West Virginia, USA., Barbier M; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA., Torrelles JB; Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institutegrid.250889.e, San Antonio, Texas, USA., Martinez I; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; West Virginia Universitygrid.268154.c Cancer Institute, Morgantown, West Virginia, USA., Martinez-Sobrido L; Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institutegrid.250889.e, San Antonio, Texas, USA., Damron FH; Department of Microbiology, Immunology, and Cell Biology, West Virginia Universitygrid.268154.c, Morgantown, West Virginia, USA.; Vaccine Development Center at West, Virginia University Health Sciences Center, Morgantown, West Virginia, USA.

Publikováno v: Journal of virology [J Virol] 2022 Mar 23; Vol. 96 (6), pp. e0218421. Date of Electronic Publication: 2022 Jan 26.

Flower lose, a cell fitness marker, predicts COVID-19 prognosis.

Autor: Yekelchyk M; Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Madan E; Champalimaud Centre for the Unknown, Lisbon, Portugal., Wilhelm J; Universities Giessen & Marburg Lung Center, German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Institute for Lung Health (ILH), Universities Giessen & Marburg Lung Center, German Center for Lung Research (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Short KR; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld, Australia., Palma AM; Champalimaud Centre for the Unknown, Lisbon, Portugal., Liao L; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark., Camacho D; Champalimaud Centre for the Unknown, Lisbon, Portugal., Nkadori E; Department of Pathology and Laboratory Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Winters MT; Department of Microbiology, Immunology & Cell Biology and WVU Cancer Institute, West Virginia University, Morgantown, WV, USA., Rice ES; Department of Microbiology, Immunology & Cell Biology and WVU Cancer Institute, West Virginia University, Morgantown, WV, USA., Rolim I; Champalimaud Centre for the Unknown, Lisbon, Portugal., Cruz-Duarte R; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Pelham CJ; Eurofins Panlabs Inc., St. Charles, MO, USA., Nagane M; Department of Biochemistry, School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Gupta K; Department of Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Chaudhary S; Department of Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Braun T; Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; Member of the German Center for Cardiovascular Research (DZHK), Greifswald, Germany., Pillappa R; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Parker MS; Department of Diagnostic Radiology and Internal Medicine, Early Detection Lung Cancer Screening Program, Thoracic Imaging Division, Thoracic Imaging Fellowship Program, VCU Health Systems, Richmond, VA, USA., Menter T; Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel and University of Basel, Basel, Switzerland., Matter M; Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel and University of Basel, Basel, Switzerland., Haslbauer JD; Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel and University of Basel, Basel, Switzerland., Tolnay M; Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel and University of Basel, Basel, Switzerland., Galior KD; Department of Pathology and Laboratory Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Matkwoskyj KA; Department of Pathology and Laboratory Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., McGregor SM; Department of Pathology and Laboratory Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Muller LK; Department of Pathology and Laboratory Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Rakha EA; Division of Cancer and Stem Cells, Department of Pathology, School of Medicine, Nottingham University Hospitals, University of Nottingham, Nottingham, UK., Lopez-Beltran A; Champalimaud Centre for the Unknown, Lisbon, Portugal.; Department of Morphological Sciences, Cordoba University, Cordoba, Spain., Drapkin R; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Graduate Program in Cell and Molecular Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Ackermann M; Institute of Pathology and Molecular Pathology, Helios University Clinic Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.; Institute of Functional and Clinical Anatomy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Fisher PB; Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.; Department of Human and Molecular Genetics, Institute of Molecular Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA., Grossman SR; Department of Internal Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA.; University of Southern California, Los Angeles, CA, USA., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.; University of Kansas Cancer Center, Kansas City, KS, USA., Kulasinghe A; The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Qld, Australia., Martinez I; Department of Microbiology, Immunology & Cell Biology and WVU Cancer Institute, West Virginia University, Morgantown, WV, USA., Marsh CB; Department of Microbiology, Immunology & Cell Biology and WVU Cancer Institute, West Virginia University, Morgantown, WV, USA., Tang B; Department of Intensive Care Medicine, Nepean Hospital, Penrith, NSW, Australia., Wicha MS; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA., Won KJ; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark.; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, University of Copenhagen, Copenhagen N, Denmark., Tzankov A; Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel and University of Basel, Basel, Switzerland., Moreno E; Champalimaud Centre for the Unknown, Lisbon, Portugal., Gogna R; Champalimaud Centre for the Unknown, Lisbon, Portugal.; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark.; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, University of Copenhagen, Copenhagen N, Denmark.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2021 Nov 08; Vol. 13 (11), pp. e13714. Date of Electronic Publication: 2021 Oct 18.