Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Wint Nandar"'
Publikováno v:
Clinical Neurophysiology. 141:S169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c2c78b6ffdf40a952f9d178c9b59396
https://doi.org/10.1016/j.clinph.2022.07.447
https://doi.org/10.1016/j.clinph.2022.07.447
Publikováno v:
In Clinical Neurophysiology September 2022 141 Supplement:S169-S169
Publikováno v:
Muscle & Nerve. 54:284-291
Introduction HMG-CoA reductase inhibitors (statins) and H63D HFE polymorphism may modify amyotrophic lateral sclerosis (ALS). We hypothesized that statins worsen phenotype in ALS mice, dependent on HFE genotype. Methods Mice harboring SOD1(G93A) hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d62339feefe8acbaef42765848aac7
https://doi.org/10.1002/mus.25048
https://doi.org/10.1002/mus.25048
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488eca1f1a42ec25b22618cf5a7f0a54
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.18
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.18
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1842(12):2413-2426
H63D HFE is associated with iron dyshomeostasis and oxidative stress; each of which plays an important role in amyotrophic lateral sclerosis (ALS) pathogenesis. To examine the role of H63D HFE in ALS, we generated a double transgenic mouse line (SOD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165832b50e344b77cc3345ff00fa3c82
Autor:
Elizabeth B. Neely, James R. Connor, Mark D. Meadowcroft, Carson J. Purnell, Amanda M. Snyder, Wint Nandar, Xuemei Huang, Anne M. Nixon, Justin P. Wright, Regina Lamendella
Publikováno v:
Journal of neurochemistry. 145(4)
Parkinson's disease is marked clinically by motor dysfunction and pathologically by dopaminergic cell loss in the substantia nigra and iron accumulation in the substantia nigra. The driver underlying iron accumulation remains unknown and could be gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7332b681250e0fb50d64810e2a23779
https://pubmed.ncbi.nlm.nih.gov/29315562
https://pubmed.ncbi.nlm.nih.gov/29315562
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832:729-741
Because of the increasing evidence that H63D HFE polymorphism appears in higher frequency in neurodegenerative diseases, we evaluated the neurological consequences of H63D HFE in vivo using mice that carry H67D HFE (homologous to human H63D). Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4d4f2f7b53c07879f738f658b549d0
https://doi.org/10.1016/j.bbadis.2013.02.009
https://doi.org/10.1016/j.bbadis.2013.02.009
Autor:
Wint Nandar, Sang Y. Lee, James R. Connor, Zachary Simmons, Mthabisi Moyo, Yiting Liu, Elizabeth B. Neely
Publikováno v:
Journal of Biological Chemistry. 286:13161-13170
A specific polymorphism in the hemochromatosis (HFE) gene, H63D, is over-represented in neurodegenerative disorders such as amyotrophic lateral sclerosis and Alzheimer disease. Mutations of HFE are best known as being associated with cellular iron ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af7f42975d5213099f642bfc46227b8
https://doi.org/10.1074/jbc.m110.170944
https://doi.org/10.1074/jbc.m110.170944
Autor:
James R. Connor, Wint Nandar
Publikováno v:
The Journal of Nutrition. 141:729S-739S
Iron accumulation in the brain and increased oxidative stress are consistent observations in many neurodegenerative diseases. Thus, we have begun examination into gene mutations or allelic variants that could be associated with loss of iron homeostas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6978a2bcdb911a0aac1b5d5ef93ae63b
https://doi.org/10.3945/jn.110.130351
https://doi.org/10.3945/jn.110.130351
Publikováno v:
Behavioural Brain Research. 196:242-247
Calcitonin gene-related peptide (CGRP) is released from the gastrointestinal tract following ingestion and causes satiety in mammals. Its effects on appetite in non-mammalian vertebrates are unreported. In Experiment 1, fasted chicks reduced food and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580bc31be6802b64af0525264739725f
https://doi.org/10.1016/j.bbr.2008.09.004
https://doi.org/10.1016/j.bbr.2008.09.004