Výsledky vyhledávání - "Winston Stauffer"

Akademický článek

The Cyclophilin Inhibitor Rencofilstat Decreases HCV-Induced Hepatocellular Carcinoma Independently of Its Antiviral Activity

Autor: Winston Stauffer, Michael Bobardt, Daren Ure, Robert Foster, Philippe Gallay

Publikováno v: Viruses, Vol 15, Iss 10, p 2099 (2023)

There is an urgent need for the identification of new drugs that inhibit HCV-induced hepatocellular carcinoma (HCC). Our work demonstrates that cyclophilin inhibitors (CypIs) represent such new drugs. We demonstrate that the nonimmunosuppressive cycl

Externí odkaz: https://doaj.org/article/7526b825a92349d892ee9d36646ce76a

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Rencofilstat, a pan-cyclophilin inhibitor, exerts diverse metabolic and transcriptional anti-tumor activities in a murine NASH-HCC model

Autor: Daren Ure, Joseph Kuo, Winston Stauffer, Lacey Haddon, Patrick Mayo, Robert Foster, Philippe Gallay

Publikováno v: Journal of Hepatology. 77:S660

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dbe08602fdcd1241e2e1d85fb5a7806
https://doi.org/10.1016/s0168-8278(22)01638-5

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Cyclophilin D knockout promotes cell death pathways in preventing HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH

Autor: Winston Stauffer, Joseph Kuo, Daren Ure, Robert Foster, Philippe Gallay

Publikováno v: Journal of Hepatology. 77:S650

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff84699028da15833b887c19a87eb1c
https://doi.org/10.1016/s0168-8278(22)01615-4

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