Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Winston M. Walters"'
Autor:
Frederic A. Vallejo, Anthony Sanchez, Branko Cuglievan, Winston M. Walters, Guillermo De Angulo, Steven Vanni, Regina M. Graham
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
High-risk neuroblastoma (NB) portends very poor prognoses in children. Targeting tumor metabolism has emerged as a novel therapeutic strategy. High levels of nicotinamide-adenine-dinucleotide (NAD+) are required for rapid cell proliferation. Nicotina
Externí odkaz:
https://doaj.org/article/708da4feb36e4c00b359be5e663ee0ec
Autor:
Eduardo A. Veliz, Anastasiia Kaplina, Sajini D. Hettiarachchi, Athina L. Yoham, Carolina Matta, Sabrin Safar, Meghana Sankaran, Esther L. Abadi, Emel Kirbas Cilingir, Frederic A. Vallejo, Winston M. Walters, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1465 (2022)
The current prognosis for glioblastoma is dismal. Treatment-resistant glioblastoma stem cells (GSCs) and the failure of most drugs to reach therapeutic levels within the tumor remain formidable obstacles to successful treatment. Chalcones are aromati
Externí odkaz:
https://doaj.org/article/e8985b1057ce471ca50d4e7b774a1aad
Autor:
Ziad Khatib, Frederic A. Vallejo, Winston M. Walters, Sumedh S. Shah, Jeffrey S. Prince, Ricardo J. Komotar, Regina M. Graham, Steven Vanni, Nicolas de Cordoba
Publikováno v:
Journal of Neuro-Oncology. 147:317-326
Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Targeting tumor metabolism has emerged as a promising-targeted therapeutic strategy for GBM and characteristically resistant GBM stem-like cells (GSCs). Ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ab70276e3952cccece81ea710b9928
https://doi.org/10.1007/s11060-020-03431-w
https://doi.org/10.1007/s11060-020-03431-w
Autor:
Frederic A, Vallejo, Sumedh S, Shah, Nicolas, de Cordoba, Winston M, Walters, Jeffrey, Prince, Ziad, Khatib, Ricardo J, Komotar, Steven, Vanni, Regina M, Graham
Publikováno v:
Journal of neuro-oncology. 147(2)
Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Targeting tumor metabolism has emerged as a promising-targeted therapeutic strategy for GBM and characteristically resistant GBM stem-like cells (GSCs).Gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3784b3520c391405f3047bcc90e512cd
https://pubmed.ncbi.nlm.nih.gov/32096068
https://pubmed.ncbi.nlm.nih.gov/32096068
Autor:
Winston M. Walters, Brian Marples, Alexis J. Musick, Gregor A. Rodriguez, Nicolas de Cordoba, Ricardo J. Komotar, Jeffrey S. Prince, Regina M. Graham, Steven Vanni, Eric Barbarite, Megan M. Marlow, Sumedh S. Shah
Publikováno v:
Cancers
Volume 11
Issue 2
Cancers, Vol 11, Iss 2, p 159 (2019)
Volume 11
Issue 2
Cancers, Vol 11, Iss 2, p 159 (2019)
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, and despite optimized treatment options, median survival remains dismal. Contemporary evidence suggests disease recurrence results from expansion of a robustly radior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ffa1028beb7d647762142688faf90d
Autor:
Robert Suter, Vasileios Stathias, Claude-Henry Volmar, Ricardo J. Komotar, Winston M. Walters, Marie E. Maloof, Regina M. Graham, Stephan C. Schürer, Michael A. Durante, Anna Jermakowicz, Nicholas J. Lyons, Sion L. Williams, Michele Forlin, Aravind Subramanian, Todd R. Golub, Nagi G. Ayad, Claes Wahlestedt, J. William Harbour, Jann N. Sarkaria, Michael E. Ivan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Glioblastoma (GBM) is the most common primary adult brain tumor. Despite extensive efforts, the median survival for GBM patients is approximately 14 months. GBM therapy could benefit greatly from patient-specific targeted therapies that maximize trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d5bd0be5ccc605475a873d56e7f7b7
https://doi.org/10.1038/s41467-018-07659-z
https://doi.org/10.1038/s41467-018-07659-z
Autor:
Spencer Summers, Winston M. Walters, Roberta Brambilla, Mariagrazia Grilli, Anna Dellarole, John R. Bethea, Danielle Bernardes, Paul D. Morton
Publikováno v:
Brain, Behavior, and Immunity. 41:65-81
Patients suffering from neuropathic pain have a higher incidence of mood disorders such as depression. Increased expression of tumor necrosis factor (TNF) has been reported in neuropathic pain and depressive-like conditions and most of the pro-inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bdb57b2440a56f0b40068dc29056f2
https://doi.org/10.1016/j.bbi.2014.04.003
https://doi.org/10.1016/j.bbi.2014.04.003
Autor:
Sumedh S. Shah, Luis E. Raez, Katrina Kostenko, Jeffrey S. Prince, Winston M. Walters, Regina M. Graham, Steven Vanni, Frederic A. Vallejo, Ingrid Torrens, Ziad Khatib
Publikováno v:
Journal of Clinical Oncology. 37:e13558-e13558
e13558 Background: Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Despite enormous efforts to elucidate the genetic and epigenetic drivers of this disease, the prognosis for patients diagnosed with GBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb083a73792af155fc3c1118246b4127
https://doi.org/10.1200/jco.2019.37.15_suppl.e13558
https://doi.org/10.1200/jco.2019.37.15_suppl.e13558
Autor:
Winston M. Walters, Eduardo A. Veliz, Stephan C. Schürer, Roger M. Leblanc, Lorenzo Sansalone, Regina M. Graham, Steven Vanni, Vasileios Stathias, Nadia G. Myrthil, Ingrid Torrens
Publikováno v:
Cancers, Vol 11, Iss 3, p 357 (2019)
Cancers
Volume 11
Issue 3
Cancers
Volume 11
Issue 3
Glioblastoma (GBM) has a dismal prognosis and successful elimination of GBM stem cells (GSCs) is a high-priority as these cells are responsible for tumor regrowth following therapy and ultimately patient relapse. Natural products and their derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d1ed7475fefdf432a37962adce2f9c
https://doi.org/10.3390/cancers11030357
https://doi.org/10.3390/cancers11030357
Autor:
Summer S. Berge, Winston M. Walters, Anna Dellarole, Paul D. Morton, Michelle H. Theus, John R. Bethea
Publikováno v:
Journal of Neuroscience. 33:9932-9936
Peripheral myelination is a dynamic process orchestrated by axons and Schwann cells. Although the signaling mechanisms governing myelination are not fully understood, NF-κB activation in Schwann cells has been implicated as a key regulator in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffbf19bb505625c70bed77cef488647
https://doi.org/10.1523/jneurosci.2483-12.2013
https://doi.org/10.1523/jneurosci.2483-12.2013