Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Winston Haynes"'
Autor:
Michael Mullin, James McClory, Winston Haynes, Justin Grace, Nathan Robertson, Gino van Heeke
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTThe development of bispecific antibodies that bind at least two different targets relies on bringing together multiple binding domains with different binding properties and biophysical characteristics to produce a drug-like therapeutic. These
Externí odkaz:
https://doaj.org/article/01baed59c39a4b3285f77233b47c5e3e
Autor:
Jeffrey Huang, Sumanta Pal, Tanya Dorff, Owen T M Chan, Hideki Furuya, Ian Pagano, Yosuke Hirasawa, Jared Acoba, David Tamura, Minlu Zhang, Rebecca Waitz, Abhilash Dhal, Winston Haynes, John Shon, Mark Scholz, Charles Rosser
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background Combining an immune checkpoint inhibitor with a tumor vaccine may modulate the immune system to leverage complementary mechanisms of action that lead to sustained T-cell activation and a potent prolonged immunotherapeutic response in metas
Externí odkaz:
https://doaj.org/article/777a359f9d2d4d038339263ff0f9ad51
Autor:
Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D. Azad, Erika Bongen, Winston Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Cell type deconvolution from bulk expression data rely on a reference expression matrix. Here, the authors introduce a basis matrix built using data from both healthy and diseased samples profiled on 42 platforms, reducing biases introduced by single
Externí odkaz:
https://doaj.org/article/6f12c79a854b4734a673942857dc8a8a
Autor:
Aurelie Tomczak, Jonathan M. Mortensen, Rainer Winnenburg, Charles Liu, Dominique T. Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, Winston Haynes, Nigam H. Shah, Mark A. Musen, Purvesh Khatri
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments. However, the two building blocks of this analysis —
Externí odkaz:
https://doaj.org/article/22ec44186f434485be70d5c0e2be2183
Autor:
Michael Snyder, Roger Higdon, Larissa Stanberry, George I. Mias, Winston Haynes, Eugene Kolker
Publikováno v:
Metabolites, Vol 3, Iss 3, Pp 741-760 (2013)
The integrative personal omics profile (iPOP) is a pioneering study that combines genomics, transcriptomics, proteomics, metabolomics and autoantibody profiles from a single individual over a 14-month period. The observation period includes two episo
Externí odkaz:
https://doaj.org/article/e290af735d6d4f42a4f8794194076b49
Autor:
Gregory J Hather, Winston Haynes, Roger Higdon, Natali Kolker, Elizabeth A Stewart, Peter Arzberger, Patrick Chain, Dawn Field, B Robert Franza, Biaoyang Lin, Folker Meyer, Vural Ozdemir, Charles V Smith, Gerald van Belle, John Wooley, Eugene Kolker
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12203 (2010)
To gauge the current commitment to scientific research in the United States of America (US), we compared federal research funding (FRF) with the US gross domestic product (GDP) and industry research spending during the past six decades. In order to a
Externí odkaz:
https://doaj.org/article/21f5d9b57168445ebaa60c1ea1f9edd0