Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Winston, Timp"'
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101121- (2024)
Externí odkaz:
https://doaj.org/article/c5edd96606024a5d8e1bcb0f394409ed
Autor:
Raghavendran Anantharam, Dylan Duchen, Andrea L. Cox, Winston Timp, David L. Thomas, Steven J. Clipman, Abraham J. Kandathil
Publikováno v:
Viruses, Vol 16, Iss 5, p 723 (2024)
Routinely used metagenomic next-generation sequencing (mNGS) techniques often fail to detect low-level viremia (4 copies/mL) and appear biased towards viruses with linear genomes. These limitations hinder the capacity to comprehensively characterize
Externí odkaz:
https://doaj.org/article/0d62f32f8b83477cbc31213597118a1f
Publikováno v:
Fruit Research, Vol 2, Iss 1, Pp 1-5 (2022)
Fragaria vesca, a wild diploid strawberry, serves as a fundamental research model for cultivated strawberry. The current reference genomes available are limited to two closely-related accessions, Hawaii 4 and CFRA2339. The widely-used model accession
Externí odkaz:
https://doaj.org/article/2cb33974d6194eb698afc2597433b6cf
Autor:
Abraham J. Kandathil, Andrea L. Cox, Kimberly Page, David Mohr, Roham Razaghi, Khalil G. Ghanem, Susan A. Tuddenham, Yu-Hsiang Hsieh, Jennifer L. Evans, Kelly E. Coller, Winston Timp, David D. Celentano, Stuart C. Ray, David L. Thomas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Spread of bloodborne infections, such as HCV and HIV, is a problem, particularly amongst people who inject drugs (PWID). Here, the authors describe and then confirm in observational PWID cohorts that those with more non-pathogenic viruses in plasma w
Externí odkaz:
https://doaj.org/article/4741ba4f9e2c4955a8b2cc8ce3271ae4
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Long-read sequencing has been shown to have advantages in structural variation (SV) detection and methylation calling. Many studies focus either on SV, methylation, or phasing of SNV; however, only the combination of variants provides a comp
Externí odkaz:
https://doaj.org/article/72a5427bf22b4cc9a5561437650c3486
Autor:
Jane X. Yeh, Yunfan Fan, Maggie L. Bartlett, Xiaoyan Zhang, Norah Sadowski, Debra A. Hauer, Winston Timp, Diane E. Griffin
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Alphaviruses are positive-sense RNA viruses that are important causes of viral encephalomyelitis. Sindbis virus (SINV), the prototype alphavirus, preferentially infects neurons in mice and is a model system for studying mechanisms of viral c
Externí odkaz:
https://doaj.org/article/e66f34ab3fd2479884dde99df6b66f4c
Autor:
Helen R. Clark, Connor McKenney, Nathan M. Livingston, Ariel Gershman, Seema Sajjan, Isaac S. Chan, Andrew J. Ewald, Winston Timp, Bin Wu, Abhyudai Singh, Sergi Regot
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Fine tuning the immune response in line with the degree of threat is central to recognition of a pathogen versus commensal bacteria. Here the authors implicate a digital all-or-nothing cell response in control of the tissue level immune response.
Externí odkaz:
https://doaj.org/article/c941a781c5064d999cddc94eed6d7777
Autor:
Alison D. Scott, Aleksey V. Zimin, Daniela Puiu, Rachael Workman, Monica Britton, Sumaira Zaman, Madison Caballero, Andrew C. Read, Adam J. Bogdanove, Emily Burns, Jill Wegrzyn, Winston Timp, Steven L. Salzberg, David B. Neale
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3907-3919 (2020)
The giant sequoia (Sequoiadendron giganteum) of California are massive, long-lived trees that grow along the U.S. Sierra Nevada mountains. Genomic data are limited in giant sequoia and producing a reference genome sequence has been an important goal
Externí odkaz:
https://doaj.org/article/860ce952a2d64d18803fdd70720cf46d
Autor:
Andrew N. Gale, Rima M. Sakhawala, Anton Levitan, Roded Sharan, Judith Berman, Winston Timp, Kyle W. Cunningham
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3859-3870 (2020)
Externí odkaz:
https://doaj.org/article/7a8952b884d4442c96ee94d5eff3e67f
Autor:
Nathan D. Olson, M. Senthil Kumar, Shan Li, Domenick J. Braccia, Stephanie Hao, Winston Timp, Marc L. Salit, O. Colin Stine, Hector Corrada Bravo
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-18 (2020)
Abstract Background There are a variety of bioinformatic pipelines and downstream analysis methods for analyzing 16S rRNA marker-gene surveys. However, appropriate assessment datasets and metrics are needed as there is limited guidance to decide betw
Externí odkaz:
https://doaj.org/article/cef4c15f23824a8e881f439db9df4a9a