Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Winship Herr"'
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0224646 (2020)
Twelve human THAP proteins share the THAP domain, an evolutionary conserved zinc-finger DNA-binding domain. Studies of different THAP proteins have indicated roles in gene transcription, cell proliferation and development. We have analyzed this prote
Externí odkaz:
https://doaj.org/article/964cd13f225c47f79e8db97346ec01b4
Autor:
Leonor Rib, Dominic Villeneuve, Shilpi Minocha, Viviane Praz, Nouria Hernandez, Nicolas Guex, Winship Herr, The CycliX Consortium
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-19 (2018)
Abstract Background Compensatory liver hyperplasia—or regeneration—induced by two-thirds partial hepatectomy (PH) permits the study of synchronized activation of mammalian gene expression, particularly in relation to cell proliferation. Here, we
Externí odkaz:
https://doaj.org/article/99e6fd4387c4487894ecb6341198cddf
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136636 (2015)
Human HCF-1 (also referred to as HCFC-1) is a transcriptional co-regulator that undergoes a complex maturation process involving extensive O-GlcNAcylation and site-specific proteolysis. HCF-1 proteolysis results in two active, noncovalently associate
Externí odkaz:
https://doaj.org/article/c0e77d87d45c40ec8b76e9dcec731d14
Autor:
Gwendal Le Martelot, Donatella Canella, Laura Symul, Eugenia Migliavacca, Federica Gilardi, Robin Liechti, Olivier Martin, Keith Harshman, Mauro Delorenzi, Béatrice Desvergne, Winship Herr, Bart Deplancke, Ueli Schibler, Jacques Rougemont, Nicolas Guex, Nouria Hernandez, Felix Naef, CycliX Consortium
Publikováno v:
PLoS Biology, Vol 10, Iss 11, p e1001442 (2012)
Interactions of cell-autonomous circadian oscillators with diurnal cycles govern the temporal compartmentalization of cell physiology in mammals. To understand the transcriptional and epigenetic basis of diurnal rhythms in mouse liver genome-wide, we
Externí odkaz:
https://doaj.org/article/39ea2125b291414090a9397d877a0053
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27479 (2011)
Repression and activation of gene transcription involves multiprotein complexes that modify chromatin structure. The integration of these complexes at regulatory sites can be assisted by co-factors that link them to DNA-bound transcriptional regulato
Externí odkaz:
https://doaj.org/article/1045229df42442fcbf064e7e8f6ca0c9
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9020 (2010)
BACKGROUND: The human herpes simplex virus-associated host cell factor 1 (HCF-1) is a conserved human transcriptional co-regulator that links positive and negative histone modifying activities with sequence-specific DNA-binding transcription factors.
Externí odkaz:
https://doaj.org/article/78c5430138d547d7bf1c3c5b19b0693d
Autor:
Soyoung Lee, Virginie Horn, Eric Julien, Yi Liu, Joanna Wysocka, Bruce Bowerman, Michael O Hengartner, Winship Herr
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1213 (2007)
The human herpes simplex virus (HSV) host cell factor HCF-1 is a transcriptional coregulator that associates with both histone methyl- and acetyltransferases, and a histone deacetylase and regulates cell proliferation and division. In HSV-infected ce
Externí odkaz:
https://doaj.org/article/af2f666d23394f43ae05dd245cf4f774
Autor:
Winship Herr
Publikováno v:
Genes & Development. 37:11-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d59f5b4bdae5268bedf41d692554615
https://doi.org/10.1101/gad.350475.123
https://doi.org/10.1101/gad.350475.123
Autor:
Shilpi Minocha, Winship Herr
Publikováno v:
Developmental neurobiology, vol. 79, no. 6, pp. 578-595
Developmental Neurobiology
Developmental Neurobiology
Formation of the cerebral cortex and commissures involves a complex developmental process defined by multiple molecular mechanisms governing proliferation of neuronal and glial precursors, neuronal and glial migration, and patterning events. Failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c77c4e55ff698f1366e6310c933fbb
https://doi.org/10.1002/dneu.22704
https://doi.org/10.1002/dneu.22704
Publikováno v:
Hepatology Communications
Hepatology Communications, vol. 1, no. 9, pp. 871-885
Hepatology Communications, vol. 1, no. 9, pp. 871-885
Mammalian partial hepatectomy (PH) induces an orchestrated compensatory hyperplasia, or regeneration, in remaining tissue to restore liver mass; during this process, liver functions are maintained. We probed this process in mice with feeding- and lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e431f39593fff077b00384f4e3ace36
http://europepmc.org/articles/PMC5721458
http://europepmc.org/articles/PMC5721458