Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Winnok H, De Vos"'
Autor:
Cédric H. G. Neutel, Callan D. Wesley, Cindy van Loo, Céline Civati, Freke Mertens, Michelle Zurek, Anja Verhulst, Isabel Pintelon, Winnok H. De Vos, Bart Spronck, Lynn Roth, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Calciprotein particles (CPPs) are an endogenous buffering system, clearing excessive amounts of Ca2+ and PO4 3- from the circulation and thereby preventing ectopic mineralization. CPPs circulate as primary CPPs (CPP1), which are small spheri
Externí odkaz:
https://doaj.org/article/ec219c4be4484da5ac08fecee8cd9237
Autor:
Laura Téblick, Marijana Lipovac, Freya Molenberghs, Peter Delputte, Winnok H. De Vos, Alex Vorsters
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTHuman papillomavirus (HPV) vaccines, primarily relying on neutralizing antibodies, have proven highly effective. Recently, HPV-specific antibodies have been detected in the female genital tract secretions captured by first-void urine (FVU), o
Externí odkaz:
https://doaj.org/article/6124eafab9954e1093d1587a1d45969f
Autor:
Tamara Vasilkovska, Marlies Verschuuren, Dorian Pustina, Monica vanden Berg, Johan Van Audekerke, Isabel Pintelon, Roger Cachope, Winnok H. De Vos, Annemie Van der Linden, Mohit H. Adhikari, Marleen Verhoye
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Huntington's disease (HD) is marked by irreversible loss of neuronal function for which currently no availability for disease‐modifying treatment exists. Advances in the understanding of disease progression can aid biomarker dev
Externí odkaz:
https://doaj.org/article/a1e253df09ce4de680b11b9b36934d56
Autor:
Jonas Govaerts, Elise Van Breedam, Sarah De Beuckeleer, Charlotte Goethals, Claudio Peter D’Incal, Julia Di Stefano, Siebe Van Calster, Tamariche Buyle-Huybrecht, Marlies Boeren, Hans De Reu, Søren R. Paludan, Marc Thiry, Marielle Lebrun, Catherine Sadzot-Delvaux, Helena Motaln, Boris Rogelj, Johan Van Weyenbergh, Winnok H. De Vos, Wim Vanden Berghe, Benson Ogunjimi, Peter Delputte, Peter Ponsaerts
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Varicella-zoster virus (VZV) encephalitis and meningitis are potential central nervous system (CNS) complications following primary VZV infection or reactivation. With Type-I interferon (IFN) signalling being an important first line cellular defence
Externí odkaz:
https://doaj.org/article/a886acf2bf824812b60e03bc4e9326a1
Autor:
Tamara Vasilkovska, Somaie Salajeghe, Verdi Vanreusel, Johan Van Audekerke, Marlies Verschuuren, Lydiane Hirschler, Jan Warnking, Isabel Pintelon, Dorian Pustina, Roger Cachope, Ladislav Mrzljak, Ignacio Muñoz-Sanjuan, Emmanuel L. Barbier, Winnok H. De Vos, Annemie Van der Linden, Marleen Verhoye
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Background Huntington’s disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex. Alterations in the neurovascular coupling system have
Externí odkaz:
https://doaj.org/article/dd615e2f7fa549b7ab357d5b25a4d85d
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102957- (2024)
Summary: Neurological disorders are defined by synaptic dysfunction. We present a workflow to quantify morphological and functional aspects of synaptic connectivity in neuronal cultures and obtain an integrated readout. We describe steps for measurin
Externí odkaz:
https://doaj.org/article/cd3a05fbba87465e94bba757e597ca52
Autor:
Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 89-104 (2024)
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown. Given its potential relevance for early diagnosis an
Externí odkaz:
https://doaj.org/article/9e6f75de89f84982823a97136cab22fe
Autor:
Monica van den Berg, Mohit H. Adhikari, Marlies Verschuuren, Isabel Pintelon, Tamara Vasilkovska, Johan Van Audekerke, Stephan Missault, Loran Heymans, Peter Ponsaerts, Winnok H. De Vos, Annemie Van der Linden, Georgios A. Keliris, Marleen Verhoye
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background Imbalanced synaptic transmission appears to be an early driver in Alzheimer’s disease (AD) leading to brain network alterations. Early detection of altered synaptic transmission and insight into mechanisms causing early synaptic
Externí odkaz:
https://doaj.org/article/f5f8e0376a9e4e1e8fae067453091d23
Autor:
Auchi Inalegwu, Bart Cuypers, Jürgen Claesen, Ann Janssen, Amelie Coolkens, Sarah Baatout, Kris Laukens, Winnok H. De Vos, Roel Quintens
Publikováno v:
Molecular Oncology, Vol 16, Iss 19, Pp 3410-3435 (2022)
Radiotherapy is the standard of care for breast cancer. However, surviving radioresistant cells can repopulate following treatment and provoke relapse. Better understanding of the molecular mechanisms of radiation resistance may help to improve treat
Externí odkaz:
https://doaj.org/article/65577c9f7e304b9b8713ac0344f9c9d7
Autor:
Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H. De Vos, Emmanuel Valjent, Bálazs Gaszner, Ann Van Eeckhaut, Ilse Smolders, Dimitri De Bundel
Publikováno v:
Open Biology, Vol 13, Iss 6 (2023)
Neuromedin U (NMU) is an evolutionary conserved neuropeptide that has been implicated in multiple processes, such as circadian regulation, energy homeostasis, reward processing and stress coping. Although the central expression of NMU has been addres
Externí odkaz:
https://doaj.org/article/26de393b757b43169dd0b8e8bb418d2a