Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Winnie Wefelmeyer"'
The functional heterogeneity of hippocampal CA3 pyramidal neurons has emerged as a key aspect of circuit function. Here, we explored the effects of long-term cholinergic activity on the functional heterogeneity of CA3 pyramidal neurons in organotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d2cde18452ec4487c05f42ef69b2da
https://doi.org/10.1101/2022.04.04.486716
https://doi.org/10.1101/2022.04.04.486716
Publikováno v:
Neuroforum. 25:49-60
The axon initial segment (AIS) is a crucial axonal domain for neuronal function – it allows neurons to generate action potentials, maintain their polarity or modulate their own excitability, thereby adapting to sudden and more long-term changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ef3433e9040ee8751bc6c6a804ee3e
https://doi.org/10.1515/nf-2018-0023
https://doi.org/10.1515/nf-2018-0023
Autor:
Juan Burrone, Victoria Gonzalez Sabater, Alejandro Pan-Vazquez, Guilherme Neves, Winnie Wefelmeyer
Publikováno v:
Neuron. 106:265-276.e6
Summary The activity-dependent rules that govern the wiring of GABAergic interneurons are not well understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control pyramidal cell output through axo-axonic synapses that target the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d880cce3b7259425833ec2974af42d34
https://doi.org/10.1016/j.neuron.2020.01.037
https://doi.org/10.1016/j.neuron.2020.01.037
GABAergic interneurons are chiefly responsible for controlling the activity of local circuits in the cortex1,2. However, the rules that govern the wiring of interneurons are not well understood3. Chandelier cells (ChCs) are a type of GABAergic intern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0838c223084fb0102dca5a526de5d528
Autor:
Rebecca, Wright, Sarah E, Newey, Andrei, Ilie, Winnie, Wefelmeyer, Joseph V, Raimondo, Rachel, Ginham, R A Jeffrey, Mcllhinney, Colin J, Akerman
Publikováno v:
The Journal of Neuroscience
GABAB receptors are G-protein-coupled receptors that mediate inhibitory synaptic actions through a series of downstream target proteins. It is increasingly appreciated that the GABAB receptor forms part of larger signaling complexes, which enable the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b156d7747d990d4144ffb6cf2614bbc
https://pubmed.ncbi.nlm.nih.gov/28450542
https://pubmed.ncbi.nlm.nih.gov/28450542
Publikováno v:
Trends in Neurosciences
Neurons in the brain are highly plastic, allowing an organism to learn and adapt to its environment. However, this ongoing plasticity is also inherently unstable, potentially leading to aberrant levels of circuit activity. Homeostatic forms of plasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49196b29347f9739e586fa1ad4770989
https://pubmed.ncbi.nlm.nih.gov/27637565
https://pubmed.ncbi.nlm.nih.gov/27637565
Autor:
Juan Burrone, Winnie Wefelmeyer
Publikováno v:
Proceedings of the National Academy of Sciences. 112
We welcome the intent of the letter by Hoy and Fitzgerald (1) in response to our paper (2), linking basic research to clinical findings, but we also recommend caution when doing this. Hoy and Fitzgerald (1) wish to explain the discrepancy they see wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f35cee67de125009d13e9c2b8f1c0f4
https://doi.org/10.1073/pnas.1516941112
https://doi.org/10.1073/pnas.1516941112
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 5 (2012)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
The regulation of hydrogen ion concentration (pH) is fundamental to cell viability, metabolism, and enzymatic function. Within the nervous system, the control of pH is also involved in diverse and dynamic processes including development, synaptic tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb46617d7a8a14a8822928cb828986b
https://doi.org/10.3389/fnmol.2012.00068
https://doi.org/10.3389/fnmol.2012.00068
Autor:
Winnie Wefelmeyer
Publikováno v:
The Journal of Neuroscience. 27:10649-10650
Neurotransmitters play a key role in neuronal development. One particularly interesting neurotransmitter, GABA, has an excitatory function during nervous system development but becomes inhibitory in the mature brain ([Ben-Ari, 2002][1]). This transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670f54dbb6faa86248cf32e5ffb8469
https://doi.org/10.1523/jneurosci.3111-07.2007
https://doi.org/10.1523/jneurosci.3111-07.2007