Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Winnie W I Hui"'
Autor:
Sean M. Flynn, Somdutta Dhir, Krzysztof Herka, Colm Doyle, Larry Melidis, Angela Simeone, Winnie W. I. Hui, Rafael de Cesaris Araujo Tavares, Stefan Schoenfelder, David Tannahill, Shankar Balasubramanian
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement of other epigenomic
Externí odkaz:
https://doaj.org/article/64f8f18f52c349d5bcf820beb8d79a27
Autor:
Winnie W. I. Hui, Angela Simeone, Katherine G. Zyner, David Tannahill, Shankar Balasubramanian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract G-quadruplexes (G4s) are four-stranded DNA secondary structures that form in guanine-rich regions of the genome. G4s have important roles in transcription and replication and have been implicated in genome instability and cancer. Thus far mo
Externí odkaz:
https://doaj.org/article/003e83e1b961406db41ad6a9bc1d03f5
Autor:
Winnie W. I. Hui, Angela Simeone, Katherine G. Zyner, David Tannahill, Shankar Balasubramanian
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/fa17c9f7f4af47b3828a52d7935f98ee
Autor:
Giovanni Marsico, Santosh Adhikari, Oscar M. Rueda, Xiaoyun Zhang, Alejandra Bruna, Carlos Caldas, David Tannahill, Alistair Martin, Katherine G. Zyner, Shankar Balasubramanian, Robert Hänsel-Hertsch, Winnie W. I. Hui, Angela Simeone, Abigail Shea
Publikováno v:
Nature Genetics. 52:878-883
Response and resistance to anticancer therapies vary due to intertumor and intratumor heterogeneity1. Here, we map differentially enriched G-quadruplex (G4) DNA structure-forming regions (∆G4Rs) in 22 breast cancer patient-derived tumor xenograft (
Autor:
Robert, Hänsel-Hertsch, Angela, Simeone, Abigail, Shea, Winnie W I, Hui, Katherine G, Zyner, Giovanni, Marsico, Oscar M, Rueda, Alejandra, Bruna, Alistair, Martin, Xiaoyun, Zhang, Santosh, Adhikari, David, Tannahill, Carlos, Caldas, Shankar, Balasubramanian
Publikováno v:
Nature genetics. 52(9)
Response and resistance to anticancer therapies vary due to intertumor and intratumor heterogeneity
Autor:
Rossa W K Chiu, Y M Dennis Lo, Tak Y Leung, K C Allen Chan, Rezan A Kadir, Maria I New, Yvonne K Y Cheng, Wing-Shan Lee, Yu K Tong, Peiyong Jiang, Winnie W I Hui
Publikováno v:
Clinical chemistry. 63(2)
BACKGROUND Researchers have developed approaches for the noninvasive prenatal testing of single gene diseases. One approach that allows for the noninvasive assessment of both maternally and paternally inherited mutations involves the analysis of sing