Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Winnie S Liang"'
Autor:
Patricia M LoRusso, Aleksandar Sekulic, Jeffrey A Sosman, Winnie S Liang, John Carpten, David W Craig, David B Solit, Alan H Bryce, Jeffrey A Kiefer, Jessica Aldrich, Sara Nasser, Rebecca Halperin, Sara A Byron, Mary Jo Pilat, Scott A Boerner, Diane Durecki, William P D Hendricks, Daniel Enriquez, Tyler Izatt, Jonathan Keats, Christophe Legendre, Svetomir N Markovic, Amy Weise, Fatima Naveed, Jessica Schmidt, Gargi D Basu, Shobana Sekar, Jonathan Adkins, Erica Tassone, Karthigayini Sivaprakasam, Victoria Zismann, Valerie S Calvert, Emanuel F Petricoin, Leslie Anne Fecher, Christopher Lao, J Paul Eder, Nicholas J Vogelzang, Jane Perlmutter, Mark Gorman, Barbara Manica, Lisa Fox, Nicholas Schork, Daniel Zelterman, Michelle DeVeaux, Richard W Joseph, C Lance Cowey, Jeffrey M Trent
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248097 (2021)
Although combination BRAF and MEK inhibitors are highly effective for the 40-50% of cutaneous metastatic melanomas harboring BRAFV600 mutations, targeted agents have been ineffective for BRAFV600wild-type (wt) metastatic melanomas. The SU2C Genomics-
Externí odkaz:
https://doaj.org/article/ea286e5ad5d3466fb04534c8639561db
Autor:
Michael E Berens, Anup Sood, Jill S Barnholtz-Sloan, John F Graf, Sanghee Cho, Seungchan Kim, Jeffrey Kiefer, Sara A Byron, Rebecca F Halperin, Sara Nasser, Jonathan Adkins, Lori Cuyugan, Karen Devine, Quinn Ostrom, Marta Couce, Leo Wolansky, Elizabeth McDonough, Shannon Schyberg, Sean Dinn, Andrew E Sloan, Michael Prados, Joanna J Phillips, Sarah J Nelson, Winnie S Liang, Yousef Al-Kofahi, Mirabela Rusu, Maria I Zavodszky, Fiona Ginty
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0219724 (2019)
Glioma is recognized to be a highly heterogeneous CNS malignancy, whose diverse cellular composition and cellular interactions have not been well characterized. To gain new clinical- and biological-insights into the genetically-bifurcated IDH1 mutant
Externí odkaz:
https://doaj.org/article/1e809134b36d47c88e669627661aa0b7
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191382 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0177814.].
Externí odkaz:
https://doaj.org/article/ef111e1b74364a4b8b41c00f6cf51a26
Autor:
Zarko Manojlovic, Austin Christofferson, Winnie S Liang, Jessica Aldrich, Megan Washington, Shukmei Wong, Daniel Rohrer, Scott Jewell, Rick A Kittles, Mary Derome, Daniel Auclair, David Wesley Craig, Jonathan Keats, John D Carpten
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007087 (2017)
Multiple Myeloma (MM) is a plasma cell malignancy with significantly greater incidence and mortality rates among African Americans (AA) compared to Caucasians (CA). The overall goal of this study is to elucidate differences in molecular alterations i
Externí odkaz:
https://doaj.org/article/d5df071b25bf42b68e8974b91e13b82d
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0177814 (2017)
Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer's disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because o
Externí odkaz:
https://doaj.org/article/f4fbb189ce6a48aa8835a0d7476623c4
Autor:
Mitesh J Borad, Mia D Champion, Jan B Egan, Winnie S Liang, Rafael Fonseca, Alan H Bryce, Ann E McCullough, Michael T Barrett, Katherine Hunt, Maitray D Patel, Scott W Young, Joseph M Collins, Alvin C Silva, Rachel M Condjella, Matthew Block, Robert R McWilliams, Konstantinos N Lazaridis, Eric W Klee, Keith C Bible, Pamela Harris, Gavin R Oliver, Jaysheel D Bhavsar, Asha A Nair, Sumit Middha, Yan Asmann, Jean-Pierre Kocher, Kimberly Schahl, Benjamin R Kipp, Emily G Barr Fritcher, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Phillips, Jackie McDonald, Jonathan Adkins, Stephen D Mastrian, Pamela Placek, Aprill T Watanabe, Janine Lobello, Haiyong Han, Daniel Von Hoff, David W Craig, A Keith Stewart, John D Carpten
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004135 (2014)
Advanced cholangiocarcinoma continues to harbor a difficult prognosis and therapeutic options have been limited. During the course of a clinical trial of whole genomic sequencing seeking druggable targets, we examined six patients with advanced chola
Externí odkaz:
https://doaj.org/article/72d9a122f58441d9a86d9254c686cd3b
Autor:
Winnie S. Liang, Brett Beaulieu-Jones, Susan Smalley, Michael Snyder, Laura H. Goetz, Nicholas J. Schork
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
In recent years, the development of sensor and wearable technologies have led to their increased adoption in clinical and health monitoring settings. One area that is in early, but promising, stages of development is the use of biosensors for therape
Externí odkaz:
https://doaj.org/article/8a5a3f2f07dd4f9082012862749da0d7
Autor:
Glen J Weiss, Winnie S Liang, Michael J Demeure, Jeff A Kiefer, Galen Hostetter, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Lori Phillips, Hollie Benson, Rebecca Reiman, Angela Baker, Vickie Marsh, Daniel D Von Hoff, John D Carpten, David W Craig
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76438 (2013)
New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies
Externí odkaz:
https://doaj.org/article/280c1289dfac456ab2cd5e066758e4d2
Autor:
Diego Mastroeni, Leonidas Chouliaras, Andrew Grover, Winnie S Liang, Kevin Hauns, Joseph Rogers, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53349 (2013)
Transcription of DNA is essential for cell maintenance and survival; inappropriate localization of proteins that are involved in transcription would be catastrophic. In Alzheimer's disease brains, and in vitro studies, we have found qualitative and q
Externí odkaz:
https://doaj.org/article/37f7bb5c09c84f67bb6ef9acc47eeb2c
Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.
Autor:
Winnie S Liang, David W Craig, John Carpten, Mitesh J Borad, Michael J Demeure, Glen J Weiss, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Michael Barrett, Lori Phillips, Hollie Benson, Waibhav Tembe, Esteban Braggio, Jeffrey A Kiefer, Christophe Legendre, Richard Posner, Galen H Hostetter, Angela Baker, Jan B Egan, Haiyong Han, Douglas Lake, Edward C Stites, Ramesh K Ramanathan, Rafael Fonseca, A Keith Stewart, Daniel Von Hoff
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e43192 (2012)
Pancreatic adenocarcinoma (PAC) is among the most lethal malignancies. While research has implicated multiple genes in disease pathogenesis, identification of therapeutic leads has been difficult and the majority of currently available therapies prov
Externí odkaz:
https://doaj.org/article/8bbd106cd51d413ca0f1e24b592ba757