Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Winnie Chua"'
Autor:
James M Cotton, Derek Kyte, Nazish Khan, Winnie Chua, Larissa Fabritz, Richard P Steeds, Yongzhong Sun, Samir Mehta, Katie Kirkham, Philip Collis, Clive Stubbs, Mary Nulty
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Aortic stenosis (AS) is common affecting >13% of adults over the age of 75 years. In people who develop symptoms, without valve replacement, prognosis is dismal with mortality as high as 50% at 1 year. In asymptomatic patients, the timin
Externí odkaz:
https://doaj.org/article/b1b10fb42f3042fcac0b07d1eccfba9d
Autor:
Winnie Chua, Victor R. Cardoso, Eduard Guasch, Moritz F. Sinner, Christoph Al-Taie, Paul Brady, Barbara Casadei, Harry J. G. M. Crijns, Elton A. M. P. Dudink, Stéphane N. Hatem, Stefan Kääb, Peter Kastner, Lluis Mont, Frantisek Nehaj, Yanish Purmah, Jasmeet S. Reyat, Ulrich Schotten, Laura C. Sommerfeld, Stef Zeemering, André Ziegler, Georgios V. Gkoutos, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Early detection of atrial fibrillation (AF) enables initiation of anticoagulation and early rhythm control therapy to reduce stroke, cardiovascular death, and heart failure. In a cross-sectional, observational study, we aimed to identify a c
Externí odkaz:
https://doaj.org/article/d1c609a3c0d54b6f920d0755d796b56f
Autor:
Joris Winters, Aaron Isaacs, Stef Zeemering, Michal Kawczynski, Bart Maesen, Jos Maessen, Elham Bidar, Bas Boukens, Ben Hermans, Arne van Hunnik, Barbara Casadei, Larissa Fabritz, Winnie Chua, Laura Sommerfeld, Eduard Guasch, Luis Mont, Montserrat Batlle, Stephane Hatem, Paulus Kirchhof, Reza Wakili, Mortiz Sinner, Monica Stoll, Andreas Goette, Sander Verheule, Ulrich Schotten
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 22 (2023)
Background Atrial cardiomyopathy (atCM) is an emerging prognostic factor in cardiovascular disease. Fibrotic remodeling, cardiomyocyte hypertrophy, and capillary density are hallmarks of atCM. The contribution of etiological factors and atrial fibril
Externí odkaz:
https://doaj.org/article/6932d4bcd95d49ddb1b11904f1cb0bf7
Autor:
Paul F. Brady, Winnie Chua, Frantisek Nehaj, Derek L. Connolly, Alya Khashaba, Yanish J. V. Purmah, Muhammad J. Ul‐Qamar, Mark R. Thomas, Chetan Varma, Renate B. Schnabel, Tanja Zeller, Larissa Fabritz, Paulus F. Kirchhof
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Natriuretic peptides are routinely quantified to diagnose heart failure (HF). Their concentrations are also elevated in atrial fibrillation (AF). To clarify their value in predicting future cardiovascular events, we measured natriuretic pe
Externí odkaz:
https://doaj.org/article/7e0ccd6ead5d413fade4e4dcc358f9c6
Autor:
Jo Howe, Winnie Chua, Emily Sumner, Bogna Drozdowska, Rosanna Laverick, Rachel L Bevins, Emilie Jean-Baptiste, Martin Russell, Pia Rotshtein, Alan M Wing
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0264678 (2022)
BackgroundApraxia and action disorganization syndrome (AADS) after stroke can disrupt activities of daily living (ADL). Occupational therapy has been effective in improving ADL performance, however, inclusion of multiple tasks means it is unclear whi
Externí odkaz:
https://doaj.org/article/267ad0a08b3249988034b7487156a66b
Autor:
Janine Dretzke, Naomi Chuchu, Winnie Chua, Larissa Fabritz, Susan Bayliss, Dipak Kotecha, Jonathan J. Deeks, Paulus Kirchhof, Yemisi Takwoingi
Publikováno v:
Systematic Reviews, Vol 8, Iss 1, Pp 1-6 (2019)
Abstract Background Atrial fibrillation (AF) is the arrhythmia most commonly diagnosed in clinical practice. It is associated with significant morbidity and mortality. Prevalence of AF and complications of AF, estimated by hospitalisations, have incr
Externí odkaz:
https://doaj.org/article/d3e3316e42b74e2ba9ac8a2a4f29f2e0
Autor:
Winnie Chua, Christina L. Easter, Eduard Guasch, Alice Sitch, Barbara Casadei, Harry J. G. M. Crijns, Doreen Haase, Stéphane Hatem, Stefan Kääb, Lluis Mont, Ulrich Schotten, Moritz F. Sinner, Karla Hemming, Jonathan J. Deeks, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Atrial fibrillation (AF) is caused by different mechanisms but current treatment strategies do not target these mechanisms. Stratified therapy based on mechanistic drivers and biomarkers of AF have the potential to improve AF prev
Externí odkaz:
https://doaj.org/article/c1105bda2ca3460d997d10d322e12e2c
Autor:
Winnie Chua, Jonathan P Law, Victor R Cardoso, Yanish Purmah, Georgiana Neculau, Muhammad Jawad-Ul-Qamar, Kalisha Russell, Ashley Turner, Samantha P Tull, Frantisek Nehaj, Paul Brady, Peter Kastner, André Ziegler, Georgios V Gkoutos, Davor Pavlovic, Charles J Ferro, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
PLoS Medicine, Vol 18, Iss 2, p e1003405 (2021)
BackgroundLarge-scale screening for atrial fibrillation (AF) requires reliable methods to identify at-risk populations. Using an experimental semi-quantitative biomarker assay, B-type natriuretic peptide (BNP) and fibroblast growth factor 23 (FGF23)
Externí odkaz:
https://doaj.org/article/d0513127f00845409b6b8df1ebe0041f
Autor:
Jasmeet S. Reyat, Winnie Chua, Victor R. Cardoso, Anika Witten, Peter M. Kastner, S. Nashitha Kabir, Moritz F. Sinner, Robin Wesselink, Andrew P. Holmes, Davor Pavlovic, Monika Stoll, Stefan Kääb, Georgios V. Gkoutos, Joris R. de Groot, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
BACKGROUND Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation.METHO
Externí odkaz:
https://doaj.org/article/f0ceb91cf1c64eb28dce8b403521e23a
Autor:
Frederique E. C. M. Peeters, Elton A. M. P. Dudink, Bob Weijs, Larissa Fabritz, Winnie Chua, Bas L. J. H. Kietselaer, Joachim E. Wildberger, Steven J. R. Meex, Paulus Kirchhof, Harry J. G. M. Crijns, Leon J. Schurgers
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
ObjectiveCirculating biomarkers are useful in detection and monitoring of cardiovascular diseases. However, their role in aortic valve disease is unclear. Mechanisms are rapidly elucidated and sex differences are suggested to be involved. Therefore,
Externí odkaz:
https://doaj.org/article/45b210fd1a4a470b97f8f0c11eb67c9c