Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Winnie Ak Lau"'
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 27:917-921
SUMMARY 1. The present review describes the actions of sensory neuropeptides on the contractility of the rat and guinea-pig prostate gland and discusses the differences in sensitivity of the smooth muscle of the prostates taken from these species to
Publikováno v:
British Journal of Pharmacology. 131:1073-1080
The aim of this study was to investigate the effects of adenine nucleosides and nucleotides on contractility of the smooth muscle of rat prostate gland. Nerve terminals within rat isolated prostatic tissues were electrically field stimulated (60 V, 0
Publikováno v:
Journal of Autonomic Pharmacology. 20:193-206
1. We review literature demonstrating (a) the presence and (b) the actions of substances that mediate or modify neuroeffector transmission to the smooth muscle of the prostrate stroma of a number of species including man. 2. In all species studied pr
Publikováno v:
Regulatory Peptides. 91:63-73
This study investigated the presence and effects of calcitonin gene-related peptide (CGRP) within the rat and guinea-pig prostate glands. Immunohistochemical studies demonstrated that CGRP immunoreactive nerve fibres are sparsely distributed througho
Publikováno v:
British Journal of Pharmacology. 130:1013-1020
1. Functional experiments have been conducted to assess the effects of acetylcholine and carbachol, and the receptors on which they act to facilitate neurotransmission to the stromal smooth muscle of the prostate gland of the guinea-pig. 2. Acetylcho
Publikováno v:
European Journal of Pharmacology. 384:25-30
The alpha(1)-adrenoceptor subtype mediating noradrenaline-induced contractions of the guinea-pig isolated prostatic smooth muscle was investigated. Noradrenaline produced concentration-dependent contractions of the tissue with a mean pD(2) value of 5
Publikováno v:
British Journal of Pharmacology. 127:1091-1098
Experiments have been conducted to investigate the actions of endothelins on the guinea-pig prostate gland. Saturation experiments with [125I]-endothelin-1 (2–800 pM) in guinea-pig prostatic homogenates indicated the presence of high affinity bindi
Publikováno v:
European Journal of Pharmacology. 272:31-38
Experiments were conducted to elucidate the mechanisms of action of endothelins in facilitating neurotransmission to the rat isolated vas deferens. Endothelin-1 and endothelin-3 potentiated field stimulation-induced contractions and those evoked by A
Publikováno v:
British Journal of Pharmacology. 101:394-398
1. Nasal resistance in anaesthetized rats was assessed by measuring air overflow during ventilation of the nasal passages at constant pressure. Nasal basal resistance was reduced in a dose-dependent manner by methoxyphenamine hydrochloride (0.01-30 m
Publikováno v:
European journal of pharmacology. 403(1-2)
Endothelin-1 elicited tonic contractions of rat prostatic smooth muscle that were unaffected by prazosin (0.5 microM), tetrodotoxin (1 microM) or guanethidine (10 microM). The rank order of potency of the endothelin isopeptides was endothelin-1>endot