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Multimodal MRI-derived phenotypes in preclinical Alzheimer’s Disease: results from the EPAD cohort

Autor: Lorenzini, L., Ingala, S., Wink, A. M., Kuijer, J. P. A., Wottschel, V., Sudre, C. H., Haller, S., Molinuevo, J. L., Gispert, J. D., Cash, D. M., Thomas, D. L., Vos, S. B., Ferran, P., Petr, J., Wolz, R., Palombit, A., Schwarz, A. J., Chételat, G., Payoux, P., Di Perri, C., Pernet, C., Frisoni, G., Fox, N. C., Ritchie, C., Wardlaw, J., Waldman, A., Barkhof, F., Mutsaerts, H. J. M. M.

Publikováno v: ISMRM '22: ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United Kingdom
ISMRM '22: ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United KingdomProceedings of the ISMRM 30th Annual Meeting & Exhibition

Image-derived phenotypes (IDPs) from multimodal MRI sequences constitute an important resource that allows the characterization of brain alterations in the early stages of Alzheimer diseases and other neurodegenerative conditions. Here, we showed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d08b9d8e9a6830688f02f773f830947
https://www.hzdr.de/publications/Publ-34738-2

Mind the gap: from neurons to networks to outcomes in multiple sclerosis

Autor: Chard, D. T., Alahmadi, A. A. S., Audoin, B., Charalambous, T., Enzinger, C., Hulst, H. E., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Schoonheim, M. M., Tijms, B., Tur, C., Gandini Wheeler-Kingshott, C. A. M., Wink, A. M., Ciccarelli, O., Barkhof, F., De Stefano, N., Filippi, M., Frederiksen, J. L., Gasperini, C., Kappos, L., Palace, J., Yousry, T., Vrenken, H.

Publikováno v: Nature Reviews Neurology
Nature Reviews Neurology, 2021, 17 (3), pp.173-184. ⟨10.1038/s41582-020-00439-8⟩
Nature Reviews Neurology, Nature Publishing Group, 2021, 17 (3), pp.173-184. ⟨10.1038/s41582-020-00439-8⟩
Chard, D T, Alahmadi, A A S, Audoin, B, Charalambous, T, Enzinger, C, Hulst, H E, Rocca, M A, Rovira, À, Sastre-Garriga, J, Schoonheim, M M, Tijms, B, Tur, C, Gandini Wheeler-Kingshott, C A M, Wink, A M, Ciccarelli, O, Barkhof, F & MAGNIMS Study Group 2021, ' Mind the gap : from neurons to networks to outcomes in multiple sclerosis ', Nature Reviews Neurology, vol. 17, no. 3, pp. 173-184 . https://doi.org/10.1038/s41582-020-00439-8

MRI studies have provided valuable insights into the structure and function of neural networks, particularly in health and in classical neurodegenerative conditions such as Alzheimer disease. However, such work is also highly relevant in other diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4b8f18b094eae2c3158f41a982db51
https://amu.hal.science/hal-03501361

Neuroimaging Pre-Processing and Quality Control for The European Prevention of Alzheimer's Dementia (EPAD) Cohort Study

Autor: Lorenzini, L., Ingala, S., Wink, A. M., Kuijer, J., Wottschel, V., Sudre, C., Haller, S., Molinuevo, J. L., Gispert, J. D., Cash, D., Thomas, D., Vos, S., Prados Carrasco, F., Petr, J., Wolz, R., Palombit, A., Schwarz, A., Chételat, G., Payoux, P., Di Perri, C., Pernet, C., Giovanni, F., Fox, N., Ritchie, C., Wardlaw, J., Waldman, A., Barkhof, F., Mutsaerts, H.

Publikováno v: ISMRM '21: Proceedings of the ISMRM 29th Annual Meeting & Exhibition, 15.-20.05.2021, Virtual, Virtual

The neuroimaging community strives to obtain large data cohorts, usually through association within consortia spanning different sites and countries. This results in increased variability of acquisition parameters and scan quality, which can affect i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1c1261d3b08cd82e063421545033d390
https://www.hzdr.de/publications/Publ-33515-2

Multi-tracer model for staging cortical amyloid deposition using PET imaging

Autor: Collij, L. E., Markiewicz, P., Golla, S. S. V., Wottschel, V., Wink, A. M., Visser, P. J., Teunissen, C. E., Lammertsma, A. A., Scheltens, P., van der Flier, W. M., Boellaard, R., Heeman, F., van Berckel, B. N. M., Molinuevo, J. L., Gispert, J. D., Schmidt, M. E., Bsarkhof, F., Alves, I. L., ALFA Study for the Alzheimer’s Disease Neuroimaging Initiative, Salvadó, G., Ingala, S., Altomare, D., Wilde, A., Konijnenberg, E., van Buchem, M., Yaqub, M.

Publikováno v: UCL Discovery
Neurology (2020) (In press).

OBJECTIVE: To develop and evaluate a model for staging cortical amyloid deposition using PET with high generalizability. METHODS: 3027 subjects (1763 Cognitively Unimpaired (CU), 658 Impaired, 467 Alzheimer's disease (AD) dementia, 111 non-AD dementi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______322::d2f4a94ddb404bf915c188467909b217
https://discovery.ucl.ac.uk/id/eprint/10106881/