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Multimodal MRI-derived phenotypes in preclinical Alzheimer’s Disease: results from the EPAD cohort

Autor: Lorenzini, L., Ingala, S., Wink, A. M., Kuijer, J. P. A., Wottschel, V., Sudre, C. H., Haller, S., Molinuevo, J. L., Gispert, J. D., Cash, D. M., Thomas, D. L., Vos, S. B., Ferran, P., Petr, J., Wolz, R., Palombit, A., Schwarz, A. J., Chételat, G., Payoux, P., Di Perri, C., Pernet, C., Frisoni, G., Fox, N. C., Ritchie, C., Wardlaw, J., Waldman, A., Barkhof, F., Mutsaerts, H. J. M. M.

Publikováno v: ISMRM '22: ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United Kingdom
ISMRM '22: ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United KingdomProceedings of the ISMRM 30th Annual Meeting & Exhibition

Image-derived phenotypes (IDPs) from multimodal MRI sequences constitute an important resource that allows the characterization of brain alterations in the early stages of Alzheimer diseases and other neurodegenerative conditions. Here, we showed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d08b9d8e9a6830688f02f773f830947
https://www.hzdr.de/publications/Publ-34738-2

Mind the gap: from neurons to networks to outcomes in multiple sclerosis

Autor: Chard, D. T., Alahmadi, A. A. S., Audoin, B., Charalambous, T., Enzinger, C., Hulst, H. E., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Schoonheim, M. M., Tijms, B., Tur, C., Gandini Wheeler-Kingshott, C. A. M., Wink, A. M., Ciccarelli, O., Barkhof, F., De Stefano, N., Filippi, M., Frederiksen, J. L., Gasperini, C., Kappos, L., Palace, J., Yousry, T., Vrenken, H.

Publikováno v: Nature Reviews Neurology
Nature Reviews Neurology, 2021, 17 (3), pp.173-184. ⟨10.1038/s41582-020-00439-8⟩
Nature Reviews Neurology, Nature Publishing Group, 2021, 17 (3), pp.173-184. ⟨10.1038/s41582-020-00439-8⟩
Chard, D T, Alahmadi, A A S, Audoin, B, Charalambous, T, Enzinger, C, Hulst, H E, Rocca, M A, Rovira, À, Sastre-Garriga, J, Schoonheim, M M, Tijms, B, Tur, C, Gandini Wheeler-Kingshott, C A M, Wink, A M, Ciccarelli, O, Barkhof, F & MAGNIMS Study Group 2021, ' Mind the gap : from neurons to networks to outcomes in multiple sclerosis ', Nature Reviews Neurology, vol. 17, no. 3, pp. 173-184 . https://doi.org/10.1038/s41582-020-00439-8

MRI studies have provided valuable insights into the structure and function of neural networks, particularly in health and in classical neurodegenerative conditions such as Alzheimer disease. However, such work is also highly relevant in other diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4b8f18b094eae2c3158f41a982db51
https://amu.hal.science/hal-03501361

Generating virtual brains for MRI-based 3D cerebral blood flow simulations

Autor: Józsa, T., Petr, J., Wink, A. M., Barkhof, F., Mutsaerts, H., Payne, S.

Publikováno v: ISMRM '21: Proceedings of the ISMRM 29th Annual Meeting & Exhibition, 15.-20.05.2021, Virtual, Virtual

Human brain perfusion simulations have been limited to less than five patient-specific cases. We propose a pipeline based on MRI to overcome this limitation. Computational geometry is adjusted using T1-weighted MRI, and the perfusion model parameters

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5614bd32a767938712a2bc1e646efb9e
https://www.hzdr.de/publications/Publ-33514-1

Temporal ordering of multimodal biomarker abnormality in multiple sclerosis

Autor: Dekker, I., Schoonheim, M. M., Venkatraghavan, V., Eijlers, A. J. C., Brouwer, I., Wattjes, M. P., Wink, A. M., Geurts, J. J. G., Uitdehaag, B. M. J., Oxtoby, N. P., Vrenken, H., Killestein, J., Barkhof, F., Wottschel, V.

Publikováno v: Dekker, I, Schoonheim, M M, Venkatraghavan, V, Eijlers, A J C, Brouwer, I, Wattjes, M P, Wink, A M, Geurts, J J G, Uitdehaag, B M J, Oxtoby, N P, Vrenken, H, Killestein, J, Barkhof, F & Wottschel, V 2019, ' Temporal ordering of multimodal biomarker abnormality in multiple sclerosis ', Multiple Sclerosis Journal, vol. 25, pp. 461-462 .
Multiple Sclerosis Journal, 25, 461-462. SAGE Publications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d252f9e12378f3b6cf3e15329bad507a
https://research.vumc.nl/en/publications/3dfc26ea-90b1-48c3-87e1-fa58038f2b09