Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Winifred W. Yau"'
Autor:
Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101266- (2021)
Objective: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence
Externí odkaz:
https://doaj.org/article/d879531f2fef46d28ca34500556eedee
Autor:
Winifred W. Yau, Kiraely Adam Wong, Jin Zhou, Nivetha Kanakaram Thimmukonda, Yajun Wu, Boon-Huat Bay, Brijesh Kumar Singh, Paul Michael Yen
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102434- (2021)
Summary: Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial
Externí odkaz:
https://doaj.org/article/28ac87c58a7c403097bab2ff00935f85
Autor:
Winifred W. Yau, Paul M. Yen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 3020 (2020)
Thermogenesis is the production of heat that occurs in all warm-blooded animals. During cold exposure, there is obligatory thermogenesis derived from body metabolism as well as adaptive thermogenesis through shivering and non-shivering mechanisms. Th
Externí odkaz:
https://doaj.org/article/30e4f32460aa4d028fc9ba494a7e6289
Autor:
Winifred W Yau, Gao Bin Chen, Jin Zhou, Joel Celio Francisco, Nivetha Kanakaram Thimmukonda, Shang Li, Brijesh Kumar Singh, Paul Michael Yen
Publikováno v:
Human Molecular Genetics.
Citrin deficiency (CD) is an inborn error of metabolism caused by loss-of-function of the mitochondrial aspartate/glutamate transporter, CITRIN, which is involved in both the urea cycle and malate–aspartate shuttle. Patients with CD develop hepatos
Autor:
Paul M. Yen, K. N. Bhanu Prakash, Shigeki Sugii, Wee Kiat Ong, Winifred W. Yau, Weiping Han, Smarajit Chakraborty, Zhihong Zhou, Sue-Anne Toh
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our understa
Autor:
Jin Zhou, Anita Boelen, Paul M. Yen, Eveline Bruinstroop, Brijesh K. Singh, Madhulika Tripathi, Winifred W. Yau
Publikováno v:
Molecular Metabolism, Vol 53, Iss, Pp 101266-(2021)
Molecular metabolism, 53:101266. Elsevier GmbH
Molecular Metabolism
Molecular metabolism, 53:101266. Elsevier GmbH
Molecular Metabolism
Objective Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence o
Autor:
Nivetha Kanakaram Thimmukonda, Paul M. Yen, Kiraely Adam Wong, Jin Zhou, Boon-Huat Bay, Yajun Wu, Winifred W. Yau, Brijesh K. Singh
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102434-(2021)
iScience
iScience
Summary Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial.
Autor:
Paul M. Yen, Winifred W. Yau
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3020, p 3020 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Thermogenesis is the production of heat that occurs in all warm-blooded animals. During cold exposure, there is obligatory thermogenesis derived from body metabolism as well as adaptive thermogenesis through shivering and non-shivering mechanisms. Th
Autor:
Lei Sun, Ronny Lesmana, Yajun Wu, Boon-Huat Bay, Winifred W. Yau, Brijesh K. Singh, Rohit A. Sinha, Jin Zhou, Shigeki Sugii, Paul M. Yen, Kiraely Adam Wong
Publikováno v:
Autophagy. 15:131-150
The thyroid hormone triiodothyronine (T3) activates thermogenesis by uncoupling electron transport from ATP synthesis in brown adipose tissue (BAT) mitochondria. Although T3 can induce thermogenesi...
Autor:
Winifred W, Yau, Brijesh K, Singh, Ronny, Lesmana, Jin, Zhou, Rohit A, Sinha, Kiraely A, Wong, Yajun, Wu, Boon-Huat, Bay, Shigeki, Sugii, Lei, Sun, Paul M, Yen
Publikováno v:
Autophagy. 15(1)
The thyroid hormone triiodothyronine (T(3)) activates thermogenesis by uncoupling electron transport from ATP synthesis in brown adipose tissue (BAT) mitochondria. Although T(3) can induce thermogenesis by sympathetic innervation, little is known abo