Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wing-Yen Wong"'
Pediatric Patients with Intravascular Devices: Polymicrobial Bloodstream Infections and Risk Factors
Publikováno v:
Journal of Pathogens, Vol 2011 (2011)
A retrospective study was conducted, including 61 patients with long-term intravascular devices (IVDs) admitted to the Childrens Hospital Los Angeles with diverse underlying diseases, different types of catheters, and culture-proven catheter-related
Externí odkaz:
https://doaj.org/article/b93034e1f3de4d09b9308fc6ba945316
Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer
Autor:
Fan Yang, Wing Yen Wong, Stephen J. Zoog, Hassibullah Akeefe, Elli Koziol, Christian Vettermann, Jennifer Holcomb, Annie Clark, Kevin Hammon, Joshua Henshaw, Nina Mitchell, Kathryn Patton, Krystal Sandza, Benjamin Kim
Publikováno v:
Gene Therapy. 29:94-105
Adeno-associated virus (AAV)-based gene therapy vectors are replication-incompetent and thus pose minimal risk for horizontal transmission or release into the environment. In studies with AAV5-FVIII-SQ (valoctocogene roxaparvovec), an investigational
Publikováno v:
Patient Related Outcome Measures.
Jennifer Quinn,1 Kathleen A Delaney,2 Wing Yen Wong,2 Wolfgang Miesbach,3 Monika Bullinger4 1BioMarin Pharmaceuticals UK Ltd, London, UK; 2BioMarin Pharmaceutical Inc., Novato, CA, USA; 3Medical Clinic 2, Institute of Transfusion Medicine, University
Autor:
Nina Mitchell, Wing Yen Wong, Federico Mingozzi, M. Benjamin Hock, Kelly Lau, Romain Hardet, Mingjin Li, Brian Long, Klaudia Kuranda, Stephen J. Zoog, Gregory M. Hayes, Becky Schweighardt, Christian Vettermann, Philippe Veron
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2021, 29 (2), pp.597-610. ⟨10.1016/j.ymthe.2020.12.008⟩
Molecular Therapy, 2021, 29 (2), pp.597-610. ⟨10.1016/j.ymthe.2020.12.008⟩
Molecular Therapy, Cell Press, 2021, 29 (2), pp.597-610. ⟨10.1016/j.ymthe.2020.12.008⟩
Molecular Therapy, 2021, 29 (2), pp.597-610. ⟨10.1016/j.ymthe.2020.12.008⟩
Evaluation of immune responses to adeno-associated virus (AAV)-mediated gene therapies prior to and following dose administration plays a key role in determining therapeutic safety and efficacy. This report describes up to 3 years of immunogenicity d
Autor:
Robert Klamroth, Gregory Hayes, Tatiana Andreeva, Keith Gregg, Takashi Suzuki, Ismail Haroon Mitha, Brandon Hardesty, Midori Shima, Toni Pollock, Patricia Slev, Johannes Oldenburg, Margareth C. Ozelo, Natalie Stieltjes, Sabine-Marie Castet, Johnny Mahlangu, Flora Peyvandi, Rashid Kazmi, Jean-François Schved, Andrew D. Leavitt, Michael Callaghan, Brigitte Pan-Petesch, Doris V. Quon, Jayson Andrews, Alex Trinh, Mingjin Li, Wing Yen Wong
Publikováno v:
Human gene therapy, vol 33, iss 7-8
Adeno-associated virus (AAV)-mediated gene therapy may provide durable protection from bleeding events and reduce treatment burden for people with hemophilia A (HA). However, pre-existing immunity against AAV may limit transduction efficiency and hen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc259e68e0fb8ab0ea147c8c6346e36
https://escholarship.org/uc/item/4fd5t2tv
https://escholarship.org/uc/item/4fd5t2tv
Autor:
Tara M Robinson, Savita Rangarajan, K. John Pasi, Michael Laffan, Emily Symington, Will Lester, Bella Madan, Wing Yen Wong, Glenn F. Pierce, Xinqun Yang, Benjamin Kim, Nina Mitchell
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 27(6)
Introduction Valoctocogene roxaparvovec is an investigational AAV5-based factor VIII (FVIII) gene therapy that has demonstrated sustained clinical benefit in people with severe haemophilia A. Aim To report safety, tolerability, efficacy, and quality
Autor:
Mimi C. Lee, Wing Yen Wong, Jennifer Quinn, Flora Peyvandi, Fatemeh Tavakkoli, Benjamin Kim, Diana Frame, Adebayo Lawal
Publikováno v:
Haemophilia
Introduction Although the clinical manifestations of severe haemophilia A (HA) are well studied, the challenges, if any, of living with mild HA are not clearly delineated to date. Aim To assess available evidence of clinical risks and societal/econom
Autor:
Sylvia Fong, Bridget Yates, Choong-Ryoul Sihn, Aras Mattis, Nina Mitchell, Su Liu, Chris Russell, Benjamin Kim, Adebayo Lawal, Savita Rangarajan, Will Lester, Stuart Bunting, Glenn Pierce, K.Joh Pasi, Wing Yen Wong
Publikováno v:
Journal of Hepatology. 77:S404
Autor:
Sylvia Fong, Bridget Yates, Choong-Ryoul Sihn, Aras N. Mattis, Nina Mitchell, Su Liu, Chris B. Russell, Benjamin Kim, Adebayo Lawal, Savita Rangarajan, Will Lester, Stuart Bunting, Glenn F. Pierce, K. John Pasi, Wing Yen Wong
Publikováno v:
Nature medicine. 28(4)
Factor VIII gene transfer with a single intravenous infusion of valoctocogene roxaparvovec (AAV5-hFVIII-SQ) has demonstrated clinical benefits lasting 5 years to date in people with severe hemophilia A. Molecular mechanisms underlying sustained AAV5-
Autor:
Chris B. Russell, Nina Mitchell, K. John Pasi, Savita Rangarajan, Wing Yen Wong, Michael Laffan, Will Lester, Bella Madan, Glenn F. Pierce, Emily Symington, Mingjin Li
BACKGROUND: Adeno-associated virus (AAV)-mediated gene therapy is under investigation as a therapeutic option for persons with hemophilia A. Efficacy and safety data include 3 years of follow-up after a single administration of AAV5-hFVIII-SQ. METHOD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fb2f488cde0f386819c674b197bcaa
http://hdl.handle.net/10044/1/75763
http://hdl.handle.net/10044/1/75763