Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wing-Tze Fan"'
Autor:
Robyn J. Levy, Jonathan A. Bernstein, Henriette Farkas, Janne Björkander, Murat Bas, Peter Schmid-Grendelmeier, David Resnick, Marco Cicardi, Charles H. Kirkpatrick, Marcus Maurer, Avner Reshef, Wolfhart Kreuz, Werner Aberer, Liying Dong, D. Hurewitz, William B Smith, Sonja Werner, Francesco Arcoleo, Shmuel Kivity, Conleth Feighery, William R. Lumry, William H. Yang, Jürgen Grabbe, Bruce Ritchie, Alejandro Malbrán, Konrad Bork, Gerald J. Gleich, Henning Bier, Thomas A. Luger, Marc A. Riedl, Duane Wombolt, Christiane Pichler, Hans F. Merk, Elias Toubi, Diego S. Fernández Romero, Martin Kaatz, Andrea Zanichelli, David Langton, Constance H. Katelaris, Christian Bull, Bernd Rosenkranz, Jens Greve, Ludovic Martin, Enrico Cillari, Thomas K. Hoffmann, Wing Tze Fan, Jens Zimmermann, Aleena Banerji, Kimberly Rosen, Paul K. Keith, Irina Kravec, Kraig W. Jacobson, Bernard Floccard, Laurence Bouillet, Krystyna Obtułowicz, Suresh Anné, Brigita Sitkauskiene, Jochen Knolle, F. Bracho, Jacques Hébert
Publikováno v:
New England Journal of Medicine. 363:532-541
BACKGROUND Hereditary angioedema is characterized by recurrent attacks of angioedema of the skin, larynx, and gastrointestinal tract. Bradykinin is the key mediator of symptoms. Icatibant is a selective bradykinin B2 receptor antagonist. METHODS In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af8b161baafcb3f5ad4eb02c7e9a646
https://doi.org/10.1056/nejmoa0906393
https://doi.org/10.1056/nejmoa0906393
Publikováno v:
Molecular and Cellular Biology. 20:2727-2733
Ras-GRF2 (GRF2) is a widely expressed, calcium-activated regulator of the small-type GTPases Ras and Rac. It is a multidomain protein composed of several recognizable sequence motifs in the following order (NH(2) to COOH): pleckstrin homology (PH), c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f34007707030a4e76fb7b9d080fc6fa
https://doi.org/10.1128/mcb.20.8.2727-2733.2000
https://doi.org/10.1128/mcb.20.8.2727-2733.2000
Publikováno v:
Molecular and Cellular Biology. 17:1396-1406
Conversion of Ras proteins into an activated GTP-bound state able to bind effector proteins is catalyzed by specific guanine nucleotide exchange factors in response to a large number of extracellular stimuli. Here we report the isolation of mouse cDN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d82d290fc0260b79bf4c597470625
https://doi.org/10.1128/mcb.17.3.1396
https://doi.org/10.1128/mcb.17.3.1396
Publikováno v:
Current Biology. (16):935-939
Ras and Rac are membrane-associated GTPases that function as molecular switches activating intracellular mitogen-activated protein kinase (MAPK) cascades and other effector pathways in response to extracellular signals [1]. Activation of Ras and Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ab053571b8d81eeb64a33036e1c0a6
Repeat treatment with icatibant for multiple hereditary angioedema attacks: FAST-2 open-label study.
Autor:
Baş, M., Greve, J., Hoffmann, T. K., Reshef, A., Aberer, W., Maurer, M., Kivity, S., Farkas, H., Floccard, B., Arcoleo, F., Martin, L., Sitkauskiene, B., Bouillet, L., Schmid‐Grendelmeier, P., Li, H., Zanichelli, A.
Publikováno v:
Allergy; Nov2013, Vol. 68 Issue 11, p1452-1459, 8p