Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Wing-Tai Cheung"'
Autor:
Kai Wang, Yan-Chun Chan, Pui-Kin So, Xing Liu, Lu Feng, Wing-Tai Cheung, Susanna Sau-Tuen Lee, Shannon Wing-Ngor Au
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100074- (2021)
Abstract: Cytosolic sulfotransferases (SULTs) catalyze the transfer of a sulfonate group from the cofactor 3’-phosphoadenosine 5’-phosphosulfate to a hydroxyl (OH) containing substrate and play a critical role in the homeostasis of endogenous com
Externí odkaz:
https://doaj.org/article/71c4eae9bc6247b2b534d2564bc7d81d
Autor:
Lu Feng, Yee-Lok Yuen, Jian Xu, Xing Liu, Martin Yan-Chun Chan, Kai Wang, Wing-Ping Fong, Wing-Tai Cheung, Susanna Sau-Tuen Lee
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1114-1131 (2017)
PPARα has been known to play a pivotal role in orchestrating lipid, glucose, and amino acid metabolism via transcriptional regulation of its target gene expression during energy deprivation. Recent evidence has also suggested that PPARα is involved
Externí odkaz:
https://doaj.org/article/221c9c11f2354c209508d66df076c479
Autor:
Susanna S.T. Lee, Wood-Yee Chan, Cherry K.C. Lo, David C.C. Wan, David S.C. Tsang, Wing-Tai Cheung
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 11, Pp 2025-2037 (2004)
The peroxisome proliferator-activated receptor α (PPARα) has been implicated as a key control of fatty acid catabolism during the cellular fasting. However, little is known regarding changes of individual fatty acids in hepatic triacylglycerol (TG)
Externí odkaz:
https://doaj.org/article/ba4d37311d7a4722b60ade3f60fbb3df
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96697 (2014)
Pre-clinical and clinical studies of therapeutic antibodies require highly specific reagents to examine their immune responses, bio-distributions, immunogenicity, and pharmacodynamics in patients. Selective antigen-mimicking anti-idiotype antibody fa
Externí odkaz:
https://doaj.org/article/1d95d5468ede469da7070e36d53780b5
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106235 (2014)
P2Y receptors are expressed in virtually all epithelia and are responsible for the control of fluid and electrolyte transport. In asthmatic inflammation, the bronchial epithelia are damaged by eosinophil-derived, highly toxic cationic proteins, such
Externí odkaz:
https://doaj.org/article/d325629f006640e99b998c7ef4d34e1c
Autor:
Lili Jiang, Gladys M K Teng, Elaine Y M Chan, Shannon W N Au, Helen Wise, Susanna S T Lee, Wing-Tai Cheung
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47016 (2012)
Despite heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR expression. Angiotensin type II (AT2) receptor
Externí odkaz:
https://doaj.org/article/0905ce27e9f2419386b82b263f9e13f8
Autor:
Man Cheng, Shirley Y W Chan, Qi Zhao, Elaine Y M Chan, Shannon W N Au, Susanna S T Lee, Wing-Tai Cheung
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27406 (2011)
Antibody repertoires for library construction are conventionally harvested from mRNAs of immune cells. To examine whether germline rearranged immunoglobulin (Ig) variable region genes could be used as source of antibody repertoire, an immunized phage
Externí odkaz:
https://doaj.org/article/2bb42588a9d643c5831a47ea44cc5971
Autor:
Xing Liu, Jian Xu, Susanna S.T. Lee, Kai Wang, Pik-Shan Li, Wing-Tai Cheung, Angus Y. Lee, Martin Yan-Chun Chan
Publikováno v:
Transgenic research. 29(5-6)
SULT2A8 is a male-predominant and liver-specific mouse cytosolic sulfotransferase (SULT) that sulfonates 7α-hydroxyl (7α-OH) bile acids in vitro. Sulfonation regulates bile acid homeostasis, which in turn regulates cholesterol and energy metabolism
Autor:
Elaine Y.M. Chan, Ying Shi, Lili Jin, Naiming Zhou, Qiang Ma, Chun Chu, Wing-Tai Cheung, Meina Sun, Zhou-Fang Li, Ka Fai To, Susanna S.T. Lee, Da-Kui Wang, Li Zhang, Helen Wise, Wei Qi
Publikováno v:
Cytokine. 102:62-75
Previously our lab has created a mouse ovarian xenograft model of copy number variation (CNV)-mediated G protein-coupled receptor (GPCR) MAS-driven tumorigenesis, and RNA profiling identified a putative chemokine tumor-induced factor (Tif). Sequence
Autor:
Xing Liu, Jian Xu, Yee-Lok Yuen, Lu Feng, Kai Wang, Susanna S.T. Lee, Wing-Tai Cheung, Wing-Ping Fong, Martin Yan-Chun Chan
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1114-1131 (2017)
PPARα has been known to play a pivotal role in orchestrating lipid, glucose, and amino acid metabolism via transcriptional regulation of its target gene expression during energy deprivation. Recent evidence has also suggested that PPARα is involved