Zobrazeno 1 - 10
of 520
pro vyhledávání: '"Wing-Kin Sung"'
Autor:
Ramesh Rajaby, Dong-Xu Liu, Chun Hang Au, Yuen-Ting Cheung, Amy Yuet Ting Lau, Qing-Yong Yang, Wing-Kin Sung
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Insertions are one of the major types of structural variations and are defined as the addition of 50 nucleotides or more into a DNA sequence. Several methods exist to detect insertions from next-generation sequencing short read data, but the
Externí odkaz:
https://doaj.org/article/8d6af67baac145ecb61f417e002794aa
Autor:
Qiannan Deng, Cheng Wang, Chwee Tat Koe, Jan Peter Heinen, Ye Sing Tan, Song Li, Cayetano Gonzalez, Wing-Kin Sung, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 20, Iss 10 (2022)
Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system
Externí odkaz:
https://doaj.org/article/bf49b0e4c14d4019b05b0a6fbf4db8d0
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Esophageal cancer (EC) remains a significant challenge globally, having the 8th highest incidence and 6th highest mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common form of EC in Asia. Crucially, more than 90% of EC cas
Externí odkaz:
https://doaj.org/article/033db0cb18bf4e38bb33e0dcc6408dda
Autor:
Fan Jiang, Yaoxin Jiang, Wenxuan Wang, Changyi Xiao, Ruiyi Lin, Tanghui Xie, Wing-Kin Sung, Shijun Li, Ivan Jakovlić, Jianhai Chen, Xiaoyong Du
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background The Muscovy duck (Cairina moschata) is an economically important duck species, with favourable growth and carcass composition parameters in comparison to other ducks. However, limited genomic resources for Muscovy duck hinder our
Externí odkaz:
https://doaj.org/article/d095cca8698340eb8425609dd542163f
Publikováno v:
Plant Methods, Vol 17, Iss 1, Pp 1-13 (2021)
Abstract Background Peach diseases can cause severe yield reduction and decreased quality for peach production. Rapid and accurate detection and identification of peach diseases is of great importance. Deep learning has been applied to detect peach d
Externí odkaz:
https://doaj.org/article/0b2833e3e2a348c9946e14de07ddb35b
Autor:
Fan Jiang, Ruiyi Lin, Changyi Xiao, Tanghui Xie, Yaoxin Jiang, Jianhai Chen, Pan Ni, Wing-Kin Sung, Jianlin Han, Xiaoyong Du, Shijun Li
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-17 (2021)
Abstract Background The most prolific duck genetic resource in the world is located in Southeast/South Asia but little is known about the domestication and complex histories of these duck populations. Results Based on whole-genome resequencing data o
Externí odkaz:
https://doaj.org/article/926e761fd92640d997f2ca0fb9f7aa69
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Peach diseases seriously affect peach yield and people’s health. The precise identification of peach diseases and the segmentation of the diseased areas can provide the basis for disease control and treatment. However, the complex background and im
Externí odkaz:
https://doaj.org/article/fb293bec272249e0ba8b51f127e05a83
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background DNA methylation is an important epigenetic modification that plays a critical role in most eukaryotic organisms. Parental alleles in haploid genomes may exhibit different methylation patterns, which can lead to different phenotype
Externí odkaz:
https://doaj.org/article/9b044548a9fa47f589403364cf402596
Autor:
Lun Zhao, Shuangqi Wang, Zhilin Cao, Weizhi Ouyang, Qing Zhang, Liang Xie, Ruiqin Zheng, Minrong Guo, Meng Ma, Zhe Hu, Wing-Kin Sung, Qifa Zhang, Guoliang Li, Xingwang Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Three-dimensional genome organization and its effect on transcription remain elusive in rice. Here, the authors map promoter–promoter interactions and heterochromatin interactions using ChIA-PET and reveal spatial correlation between the genetic re
Externí odkaz:
https://doaj.org/article/a67460ba57eb4068b142e258042f90e3
Autor:
Yu Jin, Wai Yeow Lee, Soo Ting Toh, Chandana Tennakoon, Han Chong Toh, Pierce Kah-Hoe Chow, Alexander Y.-F. Chung, Samuel S. Chong, London L.-P.-J. Ooi, Wing-Kin Sung, Caroline G.-L. Lee
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Hepatocellular carcinoma is the second most deadly cancer with late presentation and limited treatment options, highlighting an urgent need to better understand HCC to facilitate the identification of early-stage biomarkers and un
Externí odkaz:
https://doaj.org/article/6c26ddd30b8844ce8595ebdb5c208db6