Výsledky vyhledávání - "Wing-Huen A. Chow"

Nucleic acid assay system for tier II laboratories and moderately complex clinics to detect HIV in low-resource settings

Autor: Wen Tang, Huimin Kong, Ying Li, Wing Huen A. Chow, Bertrand Lemieux, Yi-Wei Tang

Publikováno v: The Journal of infectious diseases. 201

There is a clear need for an instrument-free molecular diagnostic system for detecting HIV-1 RNA or DNA that can be used in developing countries. Such a test could find utility in the early diagnosis of HIV-1 infection in infancy, as well as serve as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b07bacb38b24043d67bcb3e01cb1e6b
https://pubmed.ncbi.nlm.nih.gov/20225946

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Comparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruzi

Autor: Alan H. Fairlamb, Wing-Huen A. Chow, Deuan C. Jones, Sandra L. Oza, Antonio Ariza

Publikováno v: Molecular and Biochemical Parasitology

As part of a drug discovery programme to discover new treatments for human African trypanosomiasis, recombinant trypanothione reductase from Trypanosoma brucei has been expressed, purified and characterized. The crystal structure was solved by molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a331187e5610b0eb07e45c6a9b6e19b8
http://ora.ox.ac.uk/objects/uuid:

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Application of Isothermal Helicase-Dependent Amplification with a Disposable Detection Device in a Simple Sensitive Stool Test for Toxigenic Clostridium difficile

Autor: Yi-Wei Tang, Qimin You, Wing Huen A. Chow, Huimin Kong, Wen Tang, Cindy B. McCloskey, Yanhong Tong, Lin Hu, Ciaran P. Kelly

Enzyme immunoassays (EIAs) are commonly used for the diagnosis of cases of Clostridium difficile-associated diarrhea (CDAD). However, these EIAs have high false-negative rates, even in patients with severe clinical disease. We have developed an IsoAm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756f1a516b53aab331260d01303e1586
https://europepmc.org/articles/PMC2518740/

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Primase-based whole genome amplification

Autor: Jeonghwa Lim, Huimin Kong, Chunyang Zheng, Brendan Keenan, Xiaojing Pan, Hyun-Jin Kim, Ying Li, Bertrand Lemieux, Wing Huen A. Chow

Publikováno v: Nucleic Acids Research

In vitro DNA amplification methods, such as polymerase chain reaction (PCR), rely on synthetic oligonucleotide primers for initiation of the reaction. In vivo, primers are synthesized on-template by DNA primase. The bacteriophage T7 gene 4 protein (g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1056749ae82aab006837881ea4d88a03
https://doi.org/10.1093/nar/gkn377

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