Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Wing Yu, Fu"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no disease-modifying treatment. AD progression is characterized by cognitive decline, neuroinflammation, and accumulation of amyloid-beta (Aβ) and neurofibrillary t
Externí odkaz:
https://doaj.org/article/5e145d10ba444c13a408a1dd72b67715
Autor:
Shun-Fat Lau, Congping Chen, Wing-Yu Fu, Jianan Y. Qu, Tom H. Cheung, Amy K.Y. Fu, Nancy Y. Ip
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Impairment of microglial clearance activity contributes to beta-amyloid (Aβ) pathology in Alzheimer’s disease (AD). While the transcriptome profile of microglia directs microglial functions, how the microglial transcriptome can be regulat
Externí odkaz:
https://doaj.org/article/0c8ba80fe6cf471db7a2d58b6ec0bc11
Autor:
Shuo Gu, Wing-Yu Fu, Amy K. Y. Fu, Estella Pui Sze Tong, Fanny C. F. Ip, Xuhui Huang, Nancy Y. Ip
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract The receptor tyrosine kinase, erythropoietin-producing hepatocellular A4 (EphA4), was recently identified as a molecular target for Alzheimer’s disease (AD). We found that blockade of the interaction of the receptor and its ligands, ephrin
Externí odkaz:
https://doaj.org/article/685192b840f44ae194276059f135d92a
Autor:
Wing Yu, Fu, Tai Chan, Kwok
Publikováno v:
Facilities, 2013, Vol. 31, Issue 3/4, pp. 106-118.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/02632771311299395
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Dendrites, branched structures extending from neuronal cell soma, are specialized for processing information from other neurons. The morphogenesis of dendritic structures is spatiotemporally regulated by well-orchestrated signaling cascades. Dysregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bc4d782ed70847a80810b2421997b6
http://link.springer.com/article/10.1038/s41598-020-75264-6
http://link.springer.com/article/10.1038/s41598-020-75264-6
Publikováno v:
Neurosignals, Vol 21, Iss 1-2, Pp 55-60 (2012)
Cyclin-dependent kinase 5 (Cdk5), a member of the cyclin-dependent kinase family, is critical for regulating neural development and neuronal survival. Dysregulation of Cdk5 is associated with abnormal expression of cell cycle-related proteins during
Externí odkaz:
https://doaj.org/article/6f5b2851b15e4b8aa10678721a2eddb1
Autor:
Guangmiao Fu, Wing Yu Fu, Amy K.Y. Fu, Shun-Fat Lau, Busma W.Y. Butt, I.C.W. Chan, Nancy Y. Ip, Fanny C.F. Ip, Vincent Wai-Hin Yuen, Kwok Wang Hung
Publikováno v:
ACS chemical neuroscience. 12(22)
Alzheimer's disease (AD), the most common neurodegenerative disease, has limited treatment options. As such, extensive studies have been conducted to identify novel therapeutic approaches. We previously reported that rhynchophylline (Rhy), a small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d004401c7329dcbd325ad20f63720b3e
https://pubmed.ncbi.nlm.nih.gov/34738783
https://pubmed.ncbi.nlm.nih.gov/34738783
Autor:
Yu Chen, Zhuoyi Liang, Erkang Fei, Yuewen Chen, Xiaopu Zhou, Weiqun Fang, Wing-Yu Fu, Amy K Y Fu, Nancy Y Ip
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133115 (2015)
During development, scaffold proteins serve as important platforms for orchestrating signaling complexes to transduce extracellular stimuli into intracellular responses that regulate dendritic spine morphology and function. Axin ("axis inhibitor") is
Externí odkaz:
https://doaj.org/article/76c38a9d723e492c8a32fa9952119e37
Autor:
Wing Yu, Fu1 (AUTHOR) fuwing.yu@cpce-polyu.edu.hk, Tung Ho, Wai1 (AUTHOR), Fung Jeff Wong, Chak1 (AUTHOR)
Publikováno v:
Energy & Buildings. Oct2024, Vol. 321, pN.PAG-N.PAG. 1p.
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Major depressive disorders are emerging health problems that affect millions of people worldwide. However, treatment options and targets for drug development are limited. Impaired adult hippocampal neurogenesis is emerging as a key contributor to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ffb9a2dbc8de7d6543872abea808e8
http://link.springer.com/article/10.1038/s41598-018-38103-3
http://link.springer.com/article/10.1038/s41598-018-38103-3